Tyrosine

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ; Homo sapiens







18 Article(s)
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Title
Pub. Year
#Total Relationships
1 33393497 Insulin signaling in health and disease. 2021 Jan 4 1
2 33888713 Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer. 2021 Apr 22 1
3 31600013 Distinct roles of PIK3CA in the enrichment and maintenance of cancer stem cells in head and neck squamous cell carcinoma. 2020 Jan 1
4 31611073 Class I phosphoinositide 3-kinase (PI3K) regulatory subunits and their roles in signaling and disease. 2020 Jan 1
5 32049032 Allosteric Activation of PI3Kα Results in Dynamic Access to Catalytically Competent Conformations. 2020 Apr 7 2
6 28462395 Calmodulin and PI3K Signaling in KRAS Cancers. 2017 Mar 2
7 29211993 Single-Molecule Study Reveals How Receptor and Ras Synergistically Activate PI3Kα and PIP3 Signaling. 2017 Dec 5 1
8 26267517 Activating Mutations in PIK3CA Lead to Widespread Modulation of the Tyrosine Phosphoproteome. 2015 Sep 4 1
9 25309634 Activation of PI3Kα by physiological effectors and by oncogenic mutations: structural and dynamic effects. 2014 Mar 1 2
10 21788516 Essential role of Stat3 in PI3K-induced oncogenic transformation. 2011 Aug 9 1
11 20308428 The PI3K p110alpha isoform regulates endothelial adherens junctions via Pyk2 and Rac1. 2010 Mar 22 1
12 20593314 Structural effects of oncogenic PI3Kα mutations. 2010 1
13 17452978 KIT oncoprotein interactions in gastrointestinal stromal tumors: therapeutic relevance. 2007 Sep 27 1
14 12213328 Defective CD19-dependent signaling in B-1a and B-1b B lymphocyte subpopulations. 2002 Sep 1
15 11368773 Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells. 2001 Jun 1 1
16 10488146 JAK1-dependent phosphorylation of insulin receptor substrate-1 (IRS-1) is inhibited by IRS-1 serine phosphorylation. 1999 Sep 24 1
17 9446654 The p85 and p110 subunits of phosphatidylinositol 3-kinase-alpha are substrates, in vitro, for a constitutively associated protein tyrosine kinase in platelets. 1998 Feb 1 1
18 7492761 Regulation of platelet activation in vitro by the c-Mpl ligand, thrombopoietin. 1995 Dec 1 1