Glucose

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ; Homo sapiens







14 Article(s)
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1 33283545 The Safe Soluble Compound Dehydroascorbic Acid Inhibits Various Upstream and Downstream Effectors of PI3K and KRAS Signaling Pathways in Undruggable PIK3CA/KRAS-Mutant Colorectal Cancer Stem-Like Cells. 2021 1
2 34900474 Alpelisib-Induced Diabetic Ketoacidosis in a Non-diabetic Patient. 2021 Nov 1
3 30652258 PIK3CA Mutational Status Is Associated with High Glycolytic Activity in ER+/HER2- Early Invasive Breast Cancer: a Molecular Imaging Study Using [18F]FDG PET/CT. 2019 Oct 1
4 30051890 Suppression of insulin feedback enhances the efficacy of PI3K inhibitors. 2018 Aug 1
5 30547809 The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer. 2018 Dec 14 4
6 28396387 PIK3CA mutant tumors depend on oxoglutarate dehydrogenase. 2017 Apr 25 3
7 23826284 Polyunsaturated Fatty Acids Modulate the Association between PIK3CA-KCNMB3 Genetic Variants and Insulin Resistance. 2013 2
8 23028762 Multiple metabolic alterations exist in mutant PI3K cancers, but only glucose is essential as a nutrient source. 2012 2
9 20036247 Role of growth factor receptor transactivation in high glucose-induced increased levels of Gq/11alpha and signaling in vascular smooth muscle cells. 2010 Aug 1
10 18653476 Activity of the p110-alpha subunit of phosphatidylinositol-3-kinase is required for activation of epithelial sodium transport. 2008 Sep 1
11 15632060 Phosphatidylinositol 3-kinase-mediated effects of glucose on vacuolar H+-ATPase assembly, translocation, and acidification of intracellular compartments in renal epithelial cells. 2005 Jan 5
12 11016454 Dexamethasone-induced insulin resistance in 3T3-L1 adipocytes is due to inhibition of glucose transport rather than insulin signal transduction. 2000 Oct 1
13 11027274 Positive and negative regulation of phosphoinositide 3-kinase-dependent signaling pathways by three different gene products of the p85alpha regulatory subunit. 2000 Nov 1
14 8663584 Overexpression of catalytic subunit p110alpha of phosphatidylinositol 3-kinase increases glucose transport activity with translocation of glucose transporters in 3T3-L1 adipocytes. 1996 Jul 19 4