| 1 |
34717914 | The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds. | 2022 Jan 5 |
1 |
| 2 |
34794962 | Novel Bile Acid-Dependent Mechanisms of Hepatotoxicity Associated with Tyrosine Kinase Inhibitors. | 2022 Feb |
2 |
| 3 |
35043010 | Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets. | 2022 May |
1 |
| 4 |
35126842 | Recent updates on progressive familial intrahepatic cholestasis types 1, 2 and 3: Outcome and therapeutic strategies. | 2022 Jan 27 |
1 |
| 5 |
35149083 | Alcohol triggered bile acid disequilibrium by suppressing BSEP to sustain hepatocellular carcinoma progression. | 2022 Apr 1 |
1 |
| 6 |
35153175 | A study of exons 14, 15, and 24 of the ABCB11 gene in Egyptian children with normal GGT cholestasis. | 2022 Feb |
8 |
| 7 |
35507739 | Maralixibat for the treatment of PFIC: Long-term, IBAT inhibition in an open-label, Phase 2 study. | 2022 May 4 |
1 |
| 8 |
35523117 | Alisol B 23-acetate adjusts bile acid metabolisim via hepatic FXR-BSEP signaling activation to alleviate atherosclerosis. | 2022 Jul |
1 |
| 9 |
32634627 | A High Serum Level of Taurocholic Acid Is Correlated With the Severity and Resolution of Drug-induced Liver Injury. | 2021 May |
2 |
| 10 |
33039464 | High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell-Derived Organoids. | 2021 Feb |
1 |
| 11 |
33314224 | Letter to the Editor: Liver Cell Models for Premature Termination Codon Readthrough Analyses. | 2021 Sep |
1 |
| 12 |
33450190 | Modeling Human Bile Acid Transport and Synthesis in Stem Cell-Derived Hepatocytes with a Patient-Specific Mutation. | 2021 Feb 9 |
7 |
| 13 |
33466755 | The Bile Salt Export Pump: Molecular Structure, Study Models and Small-Molecule Drugs for the Treatment of Inherited BSEP Deficiencies. | 2021 Jan 14 |
3 |
| 14 |
33472814 | Function and Expression of Bile Salt Export Pump in Suspension Human Hepatocytes. | 2021 Apr |
6 |
| 15 |
33502191 | Machine Learning Models to Predict Inhibition of the Bile Salt Export Pump. | 2021 Feb 22 |
2 |
| 16 |
33581308 | Regulatory mechanisms of the bile salt export pump (BSEP/ABCB11) and its role in related diseases. | 2021 Nov |
6 |
| 17 |
33672718 | Molecular Regulation of Canalicular ABC Transporters. | 2021 Feb 20 |
1 |
| 18 |
33713832 | The protective role of hydrophilic tetrahydroxylated bile acids (THBA). | 2021 Jul |
1 |
| 19 |
33750401 | The ESCRT-III molecules regulate the apical targeting of bile salt export pump. | 2021 Mar 9 |
1 |
| 20 |
33782042 | Characterization of Novel Fluorescent Bile Salt Derivatives for Studying Human Bile Salt and Organic Anion Transporters. | 2021 Jun |
6 |
| 21 |
33811938 | Aquaporin gene transfer for hepatocellular cholestasis. | 2021 Sep |
4 |
| 22 |
34016879 | Mutation Analysis and Disease Features at Presentation in a Multi-Center Cohort of Children With Monogenic Cholestasis. | 2021 Aug 1 |
2 |
| 23 |
34304130 | Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR. | 2021 Sep |
1 |
| 24 |
34926449 | Arbutin Alleviates the Liver Injury of α-Naphthylisothiocyanate-induced Cholestasis Through Farnesoid X Receptor Activation. | 2021 |
1 |
| 25 |
34964797 | The role of p.Val444Ala variant in the ABCB11 gene and susceptibility to biliary atresia in Vietnamese patients. | 2021 Nov 24 |
2 |
| 26 |
31571363 | Tanshinone IIA prevents rifampicin-induced liver injury by regulating BSEP/NTCP expression via epigenetic activation of NRF2. | 2020 Jan |
2 |
| 27 |
31907698 | Metformin Disrupts Bile Acid Efflux by Repressing Bile Salt Export Pump Expression. | 2020 Jan 6 |
5 |
| 28 |
32203132 | Cryo-EM structure of human bile salts exporter ABCB11. | 2020 Jul |
1 |
| 29 |
32309332 | Changes in plasma bile acid profiles after partial internal biliary diversion in PFIC2 patients. | 2020 Mar |
4 |
| 30 |
32433800 | Functional rescue of an ABCB11 mutant by ivacaftor: A new targeted pharmacotherapy approach in bile salt export pump deficiency. | 2020 Aug |
5 |
| 31 |
32565027 | Machine learning guided association of adverse drug reactions with in vitro target-based pharmacology. | 2020 Jul |
1 |
| 32 |
32646411 | Histological demonstration of BSEP/ABCB11 inhibition in transient neonatal cholestasis: a case report. | 2020 Jul 9 |
2 |
| 33 |
32796590 | Prediction of Drug-Induced Hyperbilirubinemia by In Vitro Testing. | 2020 Aug 11 |
1 |
| 34 |
32943412 | A Two-Tiered In Vitro Approach to De-Risk Drug Candidates for Potential Bile Salt Export Pump Inhibition Liabilities in Drug Discovery. | 2020 Nov |
3 |
| 35 |
33031417 | Human ABCB1 with an ABCB11-like degenerate nucleotide binding site maintains transport activity by avoiding nucleotide occlusion. | 2020 Oct |
2 |
| 36 |
33383947 | Gene Therapy for Progressive Familial Intrahepatic Cholestasis: Current Progress and Future Prospects. | 2020 Dec 29 |
1 |
| 37 |
33763207 | Glibenclamide, ATP and metformin increases the expression of human bile salt export pump ABCB11. | 2020 |
3 |
| 38 |
33868646 | Cloning of human ABCB11 gene in E. coli required the removal of an intragenic Pribnow-Schaller Box before it's Insertion into genomic safe harbor AAVS1 site using CRISPR-Cas9. | 2020 |
2 |
| 39 |
30608704 | Effect of a Common Genetic Variant (p.V444A) in the Bile Salt Export Pump on the Inhibition of Bile Acid Transport by Cholestatic Medications. | 2019 Mar 4 |
3 |
| 40 |
30639138 | Uremic solutes modulate hepatic bile acid handling and induce mitochondrial toxicity. | 2019 Apr |
1 |
| 41 |
30784208 | Phase I study of PF‐04895162, a Kv7 channel opener, reveals unexpected hepatotoxicity in healthy subjects, but not rats or monkeys: clinical evidence of disrupted bile acid homeostasis. | 2019 Feb |
4 |
| 42 |
30930437 | Molecular Mechanisms for Protection of Hepatocytes against Bile Salt Cytotoxicity. | 2019 |
1 |
| 43 |
31015375 | Beyond an Obvious Cause of Cholestasis in a Toddler: Compound Heterozygosity for ABCB11 Mutations. | 2019 May |
1 |
| 44 |
31016647 | Vesicle- and Hepatocyte-Based Assays for Identification of Drug Candidates Inhibiting BSEP Function. | 2019 |
6 |
| 45 |
31091858 | Progressive Familial Intrahepatic Cholestasis in Korea: A Clinicopathological Study of Five Patients. | 2019 Jul |
1 |
| 46 |
31175181 | Severe Hepatotoxicity of Mithramycin Therapy Caused by Altered Expression of Hepatocellular Bile Transporters. | 2019 Aug |
2 |
| 47 |
31258056 | The Role of the Sodium-taurocholate Co-transporting Polypeptide (NTCP) and Bile Salt Export Pump (BSEP) in Related Liver Disease. | 2019 |
3 |
| 48 |
31285099 | In vitro bile acid-dependent hepatocyte toxicity assay system using human induced pluripotent stem cell-derived hepatocytes: Current status and disadvantages to overcome. | 2019 Aug |
4 |
| 49 |
31341876 | Molecular Modelling and Evaluation of Hidden Information in ABCB11 Gene Mutations. | 2019 Jun |
1 |
| 50 |
31394163 | Development of an in vitro cholestatic drug-induced liver injury evaluation system using HepG2-hNTCP-C4 cells in sandwich configuration. | 2019 Dec |
4 |