Flavonoids

prostaglandin-endoperoxide synthase 2 ; Homo sapiens







23 Article(s)
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Pub. Year
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1 34592918 New horizons in the roles and associations of COX-2 and novel natural inhibitors in cardiovascular diseases. 2021 Sep 30 1
2 30591531 Inhibition of COX-2 and EGFR by Melafolone Improves Anti-PD-1 Therapy through Vascular Normalization and PD-L1 Downregulation in Lung Cancer. 2019 Mar 2
3 31132359 Structure characteristics of flavonoids for cyclooxygenase-2 mRNA inhibition in lipopolysaccharide-induced inflammatory macrophages. 2019 Aug 5 1
4 29480373 Molecular docking, molecular modeling, and molecular dynamics studies of azaisoflavone as dual COX-2 inhibitors and TP receptor antagonists. 2018 Feb 26 1
5 28869563 Synergic Anti-Pruritus Mechanisms of Action for the Radix Sophorae Flavescentis and Fructus Cnidii Herbal Pair. 2017 Sep 4 2
6 25139581 Flavonoids inhibit COX-1 and COX-2 enzymes and cytokine/chemokine production in human whole blood. 2015 Apr 2
7 26281599 [Anti-inflammatory mechanism research of flavonoid compounds in Dalbergiae Odoriferae Lignum by module-based network analysis]. 2015 Apr 1
8 26770028 Molecular docking analysis of known flavonoids as duel COX-2 inhibitors in the context of cancer. 2015 1
9 24569980 Myricetin blocks lipoteichoic acid-induced COX-2 expression in human gingival fibroblasts. 2014 Mar 2
10 23054013 Luteolin and fisetin inhibit the effects of lipopolysaccharide obtained from Porphyromonas gingivalis in human gingival fibroblasts. 2013 Jan 1
11 23534413 Virtual and in vitro bioassay screening of phytochemical inhibitors from flavonoids and isoflavones against xanthine oxidase and cyclooxygenase-2 for gout treatment. 2013 Apr 4
12 21341175 Effects of flavonoids on prostaglandin E2 production and on COX-2 and mPGES-1 expressions in activated macrophages. 2011 Sep 1
13 19804834 Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE(2) activation. 2010 Jan 1
14 20649574 Flavonoids exert distinct modulatory actions on cyclooxygenase 2 and NF-kappaB in an intestinal epithelial cell line (IEC18). 2010 Aug 7
15 19037088 A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF-kappaB-signaling pathways. 2009 Feb 1
16 17184768 The anti-inflammatory flavones quercetin and kaempferol cause inhibition of inducible nitric oxide synthase, cyclooxygenase-2 and reactive C-protein, and down-regulation of the nuclear factor kappaB pathway in Chang Liver cells. 2007 Feb 28 2
17 17630199 The effect of flavonoids on transduction mechanisms in lipopolysaccharide-treated human gingival fibroblasts. 2007 Sep 2
18 14988445 Quercetin metabolites downregulate cyclooxygenase-2 transcription in human lymphocytes ex vivo but not in vivo. 2004 Mar 3
19 15225597 Effect of flavonoids and vitamin E on cyclooxygenase-2 (COX-2) transcription. 2004 Jul 13 5
20 15539763 Anti-inflammatory plant flavonoids and cellular action mechanisms. 2004 Nov 1
21 12144868 Downregulation of COX-2 and iNOS by amentoflavone and quercetin in A549 human lung adenocarcinoma cell line. 2002 May-Jun 1
22 11213362 Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids in macrophage J774A.1. 2001 Jan 12 4
23 10920275 Suppression by flavonoids of cyclooxygenase-2 promoter-dependent transcriptional activity in colon cancer cells: structure-activity relationship. 2000 Jul 3