Vitamin B 12

5-methyltetrahydrofolate-homocysteine methyltransferase ; Homo sapiens







97 Article(s)
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Pub. Year
#Total Relationships
1 34608838 Causes and consequences of impaired methionine synthase activity in acquired and inherited disorders of vitamin B12 metabolism. 2022 Apr 3
2 35337626 Inherited defects of cobalamin metabolism. 2022 2
3 35631199 Diagnostic and Therapeutic Perspectives Associated to Cobalamin-Dependent Metabolism and Transcobalamins' Synthesis in Solid Cancers. 2022 May 14 2
4 33529932 Methyl transfer reactions catalyzed by cobalamin-dependent enzymes: Insight from molecular docking. 2021 May 2
5 34592146 Vitamin B12 impacts amyloid beta-induced proteotoxicity by regulating the methionine/S-adenosylmethionine cycle. 2021 Sep 28 1
6 34749301 Vitamin B12 and gut-brain homeostasis in the pathophysiology of ischemic stroke. 2021 Nov 2
7 31679459 Nitrous oxide causes peripheral neuropathy in a dose dependent manner among recreational users. 2020 Feb 1
8 32068834 Analysis of fibroblasts from patients with cblC and cblG genetic defects of cobalamin metabolism reveals global dysregulation of alternative splicing. 2020 Jul 29 3
9 32289469 Genetic, epigenetic and genomic mechanisms of methionine dependency of cancer and tumor-initiating cells: What could we learn from folate and methionine cycles. 2020 Jun 2
10 32709013 Biological Activity of Pseudovitamin B12 on Cobalamin-Dependent Methylmalonyl-CoA Mutase and Methionine Synthase in Mammalian Cultured COS-7 Cells. 2020 Jul 17 2
11 32718428 Methylenetetrahydrofolate Reductase Deficiency: A Case Report. 2020 Aug 1
12 33338044 A novel gene-diet interaction promotes organismal lifespan and host protection during infection via the mitochondrial UPR. 2020 Dec 1
13 30848279 Vitamin B-12 and liver activity and expression of methionine synthase are decreased in fetuses with neural tube defects. 2019 Mar 1 2
14 31951343 An infant with an extremely rare cobalamin disorder: Methionine synthase deficiency and importance of early diagnosis and treatment. 2019 5
15 28118645 A Polymorphism in the MTRR Gene Is Associated with Early Childhood Caries and Underweight. 2017 1
16 28507011 Influence of Diet in Multiple Sclerosis: A Systematic Review. 2017 May 1
17 28572511 Clinical or ATPase domain mutations in ABCD4 disrupt the interaction between the vitamin B12-trafficking proteins ABCD4 and LMBD1. 2017 Jul 14 2
18 27457714 Complementation of Cobalamin Auxotrophy in Synechococcus sp. Strain PCC 7002 and Validation of a Putative Cobalamin Riboswitch In Vivo. 2016 Oct 1 3
19 25809485 Pathogenic mutations differentially affect the catalytic activities of the human B12-processing chaperone CblC and increase futile redox cycling. 2015 May 1 1
20 23437274 Age-dependent decrease and alternative splicing of methionine synthase mRNA in human cerebral cortex and an accelerated decrease in autism. 2013 2
21 23608310 Analysis of subcellular [57Co] cobalamin distribution in SH-SY5Y neurons and brain tissue. 2013 Jul 15 3
22 23909731 Vitamin B12 and methionine deficiencies induce genome damage measured using the cytokinesis-block micronucleus cytome assay in human B lymphoblastoid cell lines. 2013 1
23 24164324 Mechanistic insights for formation of an organometallic Co-C bond in the methyl transfer reaction catalyzed by methionine synthase. 2013 Dec 19 2
24 24352086 Neuroenhancement with vitamin B12-underestimated neurological significance. 2013 Dec 12 1
25 24470095 Cobalt: its role in health and disease. 2013 1
26 22093367 Folate (vitamin B9) and vitamin B12 and their function in the maintenance of nuclear and mitochondrial genome integrity. 2012 May 1 1
27 22422209 Leukoencephalopathies associated with disorders of cobalamin and folate metabolism. 2012 Feb 1
28 22584536 Effect of nitrous oxide exposure during surgery on the homocysteine concentrations of children. 2012 Jul 1
29 23141461 Late onset of symptoms in an atypical patient with the cblJ inborn error of vitamin B12 metabolism: diagnosis and novel mutation revealed by exome sequencing. 2012 Dec 1
30 23251906 Role of heat-shock proteins and cobalamine in maintaining methionine synthase activity. 2012 3
31 21295329 Total blood mercury, plasma homocysteine, methylmalonic acid and folate in US children aged 3-5 years, NHANES 1999-2004. 2011 Mar 15 1
32 21551270 Insights into the evolution of vitamin B12 auxotrophy from sequenced algal genomes. 2011 Oct 2
33 22022143 Genetic interactions between MTHFR (C677T), methionine synthase (A2756G, C2758G) variants with vitamin B12 and folic acid determine susceptibility to premature coronary artery disease in Indian population. 2011 Jul 1
34 20717016 Vitamin B12: the forgotten micronutrient for critical care. 2010 Nov 1
35 20876572 Structures of the human GTPase MMAA and vitamin B12-dependent methylmalonyl-CoA mutase and insight into their complex formation. 2010 Dec 3 1
36 19141696 Folate-vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency. 2009 Feb 1
37 19243433 Cobalamin uptake and reactivation occurs through specific protein interactions in the methionine synthase-methionine synthase reductase complex. 2009 Apr 1
38 19339913 A common gene variant in methionine synthase reductase is not associated with peak homocysteine concentrations after nitrous oxide anesthesia. 2009 May 2
39 19472373 Protein methylation in full length Chlamydomonas flagella. 2009 Aug 4
40 18472229 Copper deficiency myelopathy and subacute combined degeneration of the cord - why is the phenotype so similar? 2008 Aug 1
41 18594211 Two newly synthesized 5-methyltetrahydrofolate-like compounds inhibit methionine synthase activity accompanied by cell cycle arrest in G1/S phase and apoptosis in vitro. 2008 Aug 1
42 18606554 Transcobalamin in cultured fibroblasts from patients with inborn errors of vitamin B12 metabolism. 2008 Sep-Oct 1
43 18700049 Methionine synthase A2756G polymorphism may predict ulcerative colitis and methylenetetrahydrofolate reductase C677T pancolitis, in Central China. 2008 Aug 13 1
44 17343914 Naturally occurring cobalamins have antimalarial activity. 2007 May 1
45 17477549 Protein interactions in the human methionine synthase-methionine synthase reductase complex and implications for the mechanism of enzyme reactivation. 2007 Jun 12 3
46 17924667 Ligand trans influence governs conformation in cobalamin-dependent methionine synthase. 2007 Oct 30 1
47 16846473 Acquired and inherited disorders of cobalamin and folate in children. 2006 Jul 1
48 15941899 Transcobalamin 776C->G polymorphism negatively affects vitamin B-12 metabolism. 2005 Jun 1
49 15979034 Analysis of methionine synthase reductase polymorphisms for neural tube defects risk association. 2005 Jul 1
50 16051610 A B12-responsive internal ribosome entry site (IRES) element in human methionine synthase. 2005 Sep 23 2