Acetylcysteine

H2A.X variant histone ; Homo sapiens







13 Article(s)
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1 31168028 Polyhexamethylene guanidine phosphate-induced ROS-mediated DNA damage caused cell cycle arrest and apoptosis in lung epithelial cells. 2019 1
2 29115375 Persistent STAT5-mediated ROS production and involvement of aberrant p53 apoptotic signaling in the resistance of chronic myeloid leukemia to imatinib. 2018 Jan 1
3 30132044 2,4-Dimethylaniline generates phosphorylated histone H2AX in human urothelial and hepatic cells through reactive oxygen species produced by cytochrome P450 2E1. 2018 Oct 1
4 24064905 Effect of DNA damage response by quinazolinone analogue HMJ-38 on human umbilical vein endothelial cells: evidence for γH2A.X and DNA-PK-dependent pathway. 2014 Jun 1
5 21624350 ALCAPs induce mitochondrial apoptosis and activate DNA damage response by generating ROS and inhibiting topoisomerase I enzyme activity in K562 leukemia cell line. 2011 Jun 17 1
6 19486862 Cigarette sidestream smoke induces phosphorylated histone H2AX. 2009 May 31 2
7 16628006 2-deoxy-D-glucose reduces the level of constitutive activation of ATM and phosphorylation of histone H2AX. 2006 Apr 1
8 16760673 Activation of ATM and histone H2AX phosphorylation induced by mitoxantrone but not by topotecan is prevented by the antioxidant N-acetyl-L-cysteine. 2006 Aug 2
9 16820894 Constitutive histone H2AX phosphorylation on Ser-139 in cells untreated by genotoxic agents is cell-cycle phase specific and attenuated by scavenging reactive oxygen species. 2006 Aug 1
10 16861926 Nitrogen oxide-releasing aspirin induces histone H2AX phosphorylation, ATM activation and apoptosis preferentially in S-phase cells: involvement of reactive oxygen species. 2006 Aug 1
11 16872365 Extent of constitutive histone H2AX phosphorylation on Ser-139 varies in cells with different TP53 status. 2006 Aug 2
12 15173094 Synergistic effect of histone deacetylase inhibitors FK228 and m-carboxycinnamic acid bis-hydroxamide with proteasome inhibitors PSI and PS-341 against gastrointestinal adenocarcinoma cells. 2004 Jun 1 1
13 15489221 Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species. 2004 Dec 17 1