Tyrosine

signal transducer and activator of transcription 1 ; Mus musculus







92 Article(s)
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1 34923767 Hemgn Protects Hematopoietic Stem and Progenitor Cells Against Transplantation Stress Through Negatively Regulating IFN-γ Signaling. 2022 Feb 1
2 32759968 A virus-induced conformational switch of STAT1-STAT2 dimers boosts antiviral defenses. 2021 Feb 2
3 32253245 Serine Phosphorylation of the STAT1 Transactivation Domain Promotes Autoreactive B Cell and Systemic Autoimmunity Development. 2020 May 15 5
4 31237385 Activation of a protumorigenic IFNγ/STAT1/IRF-1 signaling pathway in keratinocytes following exposure to solar ultraviolet light. 2019 Sep 2
5 28626343 Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis. 2017 3
6 27631653 Role of STAT1 and Oxidative Stress in Gentamicin-Induced Hair Cell Death in Organ of Corti. 2016 Oct 1
7 25182373 E3 ubiquitin ligase NKLAM positively regulates macrophage inducible nitric oxide synthase expression. 2015 Jan 1
8 25628091 Distinctive responses of brain tumor cells to TLR2 ligands. 2015 May 2
9 23826757 A Toll-like receptor 2 ligand, Pam3CSK4, augments interferon-γ-induced nitric oxide production via a physical association between MyD88 and interferon-γ receptor in vascular endothelial cells. 2013 Nov 2
10 22413916 Exogenous nef induces proinflammatory signaling events in murine macrophages. 2012 Apr 1
11 22942432 Selective sequestration of STAT1 in the cytoplasm via phosphorylated SHP-2 ameliorates murine experimental colitis. 2012 Oct 1 4
12 21311224 Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation. 2011 Mar 1 1
13 21636857 SUMO conjugation of STAT1 protects cells from hyperresponsiveness to IFNγ. 2011 Jul 28 3
14 21670588 Caveolin-2-deficient mice show increased sensitivity to endotoxemia. 2011 Jul 1 2
15 21680779 Myeloid-derived suppressor cell inhibition of the IFN response in tumor-bearing mice. 2011 Aug 1 2
16 21833847 Activation of STAT1 in neurons following spinal cord injury in mice. 2011 Dec 1
17 20045954 Phosphorylation of signal transducer and activator of transcription 6 (STAT6) and STAT1, but not STAT3, induced by antigen inhalation in bronchial smooth muscles of sensitized mice. 2010 1
18 20424383 alpha-Viniferin suppresses the signal transducer and activation of transcription-1 (STAT-1)-inducible inflammatory genes in interferon-gamma-stimulated macrophages. 2010 1
19 20739538 A determinant of Sindbis virus neurovirulence enables efficient disruption of Jak/STAT signaling. 2010 Nov 1
20 20980634 Galectin-3 exerts cytokine-like regulatory actions through the JAK-STAT pathway. 2010 Dec 1 1
21 19922538 The benzoxathiolone LYR-71 down-regulates interferon-gamma-inducible pro-inflammatory genes by uncoupling tyrosine phosphorylation of STAT-1 in macrophages. 2009 Dec 1
22 18390731 A conserved IFN-alpha receptor tyrosine motif directs the biological response to type I IFNs. 2008 Apr 15 1
23 18453571 Antiproliferative activity of IL-27 on melanoma. 2008 May 15 1
24 18500752 Pertussis toxin induces angiogenesis in brain microvascular endothelial cells. 2008 Sep 1
25 18818378 Hyaluronan-mediated leukocyte adhesion and dextran sulfate sodium-induced colitis are attenuated in the absence of signal transducer and activator of transcription 1. 2008 Nov 1
26 17234744 Molecular analysis of the methylprednisolone-mediated inhibition of NK-cell function: evidence for different susceptibility of IL-2- versus IL-15-activated NK cells. 2007 May 1 1
27 17390082 Toll-like receptor 3 ligand-induced antiviral response in mouse osteoblastic cells. 2007 May 1
28 17928350 Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1. 2007 Dec 2
29 17997851 Sensitivity of mice to lipopolysaccharide is increased by a high saturated fat and cholesterol diet. 2007 Nov 12 1
30 16311601 Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity. 2006 Jan 1
31 16473883 The comparative roles of suppressor of cytokine signaling-1 and -3 in the inhibition and desensitization of cytokine signaling. 2006 Apr 21 2
32 16547967 1,25 Dihydroxyvitamin-D3 modulates JAK-STAT pathway in IL-12/IFNgamma axis leading to Th1 response in experimental allergic encephalomyelitis. 2006 May 15 1
33 16622004 Notch-1 up-regulation and signaling following macrophage activation modulates gene expression patterns known to affect antigen-presenting capacity and cytotoxic activity. 2006 May 1 1
34 16866871 TGF-beta1 suppresses IFN-gamma-induced NO production in macrophages by suppressing STAT1 activation and accelerating iNOS protein degradation. 2006 Aug 2
35 16912041 Contribution of interferon-beta to the murine macrophage response to the toll-like receptor 4 agonist, lipopolysaccharide. 2006 Oct 13 1
36 16953975 TLR2- and TLR4-dependent activation of STAT1 serine phosphorylation in murine macrophages is protein kinase C-delta-independent. 2006 1
37 15522878 Role of tyrosine 441 of interferon-gamma receptor subunit 1 in SOCS-1-mediated attenuation of STAT1 activation. 2005 Jan 21 9
38 15699106 Modulation of TNF-alpha gene expression by IFN-gamma and pamidronate in murine macrophages: regulation by STAT1-dependent pathways. 2005 Feb 15 1
39 15851485 A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells. 2005 May 2 1
40 15908443 WSX-1 over-expression in CD4(+) T cells leads to hyperproliferation and cytokine hyperproduction in response to TCR stimulation. 2005 Jul 1
41 16172266 Role of the protein kinase C-epsilon-Raf-1-MEK-1/2-p44/42 MAPK signaling cascade in the activation of signal transducers and activators of transcription 1 and 3 and induction of cyclooxygenase-2 after ischemic preconditioning. 2005 Sep 27 3
42 14660670 Critical role of STAT5 activation in transformation mediated by ZNF198-FGFR1. 2004 Feb 20 1
43 14734766 Macrophage-stimulating protein, the ligand for the stem cell-derived tyrosine kinase/RON receptor tyrosine kinase, inhibits IL-12 production by primary peritoneal macrophages stimulated with IFN-gamma and lipopolysaccharide. 2004 Feb 1 1
44 14742442 Analysis of SOCS-3 promoter responses to interferon gamma. 2004 Apr 2 1
45 15037019 Macrophage hypo-responsiveness to interferon-gamma in aged mice is associated with impaired signaling through Jak-STAT. 2004 Feb 2
46 15187137 Protection against progressive leishmaniasis by IFN-beta. 2004 Jun 15 1
47 15189833 Presence of permanently activated signal transducers and activators of transcription in nuclear interchromatin granules of unstimulated mouse oocytes and preimplantation embryos. 2004 Oct 1
48 15284232 Alternative activation of STAT1 and STAT3 in response to interferon-gamma. 2004 Oct 1 2
49 12686553 Toll-like receptors 2 and 4 activate STAT1 serine phosphorylation by distinct mechanisms in macrophages. 2003 Jun 20 3
50 12738234 Mechanism of cyclooxygenase-2 upregulation in late preconditioning. 2003 May 3