Niclosamide

signal transducer and activator of transcription 3 ; Homo sapiens







50 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34929248 Niclosamide inhibits hepatitis E virus through suppression of NF-kappaB signalling. 2022 Jan 1
2 33671112 An Integrated Bioinformatics Study of a Novel Niclosamide Derivative, NSC765689, a Potential GSK3β/β-Catenin/STAT3/CD44 Suppressor with Anti-Glioblastoma Properties. 2021 Feb 28 1
3 33774344 Discovery of N-substituted sulfamoylbenzamide derivatives as novel inhibitors of STAT3 signaling pathway based on Niclosamide. 2021 Jun 5 3
4 34204596 Response to Androgens and Androgen Receptor Antagonists in the Presence of Cytokines in Prostate Cancer. 2021 Jun 12 1
5 34429248 Niclosamide affects intracellular TDP-43 distribution in motor neurons, activates mitophagy, and attenuates morphological changes under stress. 2021 Dec 1
6 34434118 TRIM18-Regulated STAT3 Signaling Pathway via PTP1B Promotes Renal Epithelial-Mesenchymal Transition, Inflammation, and Fibrosis in Diabetic Kidney Disease. 2021 1
7 31894334 Niclosamide inhibits the cell proliferation and enhances the responsiveness of esophageal cancer cells to chemotherapeutic agents. 2020 Feb 2
8 31950153 Niclosamide suppresses macrophage-induced inflammation in endometriosis†. 2020 Apr 24 2
9 33002501 Noncanonical pS727 post translational modification dictates major STAT3 activation and downstream functions in breast cancer. 2020 Nov 15 1
10 33011217 Repurposing of niclosamide as a STAT3 inhibitor to enhance the anticancer effect of chemotherapeutic drugs in treating colorectal cancer. 2020 Dec 1 3
11 30329025 Endometriotic inflammatory microenvironment induced by macrophages can be targeted by niclosamide†. 2019 Feb 1 2
12 30348020 Formulation-optimization of solid lipid nanocarrier system of STAT3 inhibitor to improve its activity in triple negative breast cancer cells. 2019 Feb 1
13 30779072 EGF promotes HIF-1α expression in colorectal cancer cells and tumor metastasis by regulating phosphorylation of STAT3. 2019 Feb 3
14 31243136 Pentagalloylglucose Inhibits the Replication of Rabies Virus via Mediation of the miR-455/SOCS3/STAT3/IL-6 Pathway. 2019 Sep 15 1
15 31371076 CD133 receptor mediated delivery of STAT3 inhibitor for simultaneous elimination of cancer cells and cancer stem cells in oral squamous cell carcinoma. 2019 Aug 1
16 31383893 Niclosamide reverses adipocyte induced epithelial-mesenchymal transition in breast cancer cells via suppression of the interleukin-6/STAT3 signalling axis. 2019 Aug 5 2
17 31451218 STAT3 operates as a novel transcription factor that regulates NEDD4 in Keloid. 2019 Oct 22 3
18 31465777 Repurposing of the anti-helminthic drug niclosamide to treat melanoma and pulmonary metastasis via the STAT3 signaling pathway. 2019 Nov 4
19 31611940 Platelet-derived growth factor-BB promotes proliferation and migration of retinal microvascular pericytes by up-regulating the expression of C-X-C chemokine receptor types 4. 2019 Nov 1
20 28389414 Niclosamide: Beyond an antihelminthic drug. 2018 Jan 1
21 29251334 Niclosamide acts as a new inhibitor of vasculogenic mimicry in oral cancer through upregulation of miR-124 and downregulation of STAT3. 2018 Feb 4
22 29278854 Overexpression of ALK4 inhibits cell proliferation and migration through the inactivation of JAK/STAT3 signaling pathway in glioma. 2018 Feb 1
23 29545902 JAK2/STAT3 pathway as a therapeutic target in ovarian cancers. 2018 Apr 3
24 29603892 Niclosamide, a Drug with Many (Re)purposes. 2018 Jun 6 1
25 29721216 Correction: Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer. 2018 Apr 10 1
26 29783777 Preferential Inhibition of Wnt/β-Catenin Signaling by Novel Benzimidazole Compounds in Triple-Negative Breast Cancer. 2018 May 20 1
27 29855616 Activation of STAT3 and Bcl-2 and reduction of reactive oxygen species (ROS) promote radioresistance in breast cancer and overcome of radioresistance with niclosamide. 2018 Sep 4
28 30125275 The antiparasitic drug niclosamide inhibits dengue virus infection by interfering with endosomal acidification independent of mTOR. 2018 Aug 2
29 30272302 Taurolidine promotes cell apoptosis by enhancing GRIM‑19 expression in liver cancer. 2018 Dec 1
30 30519314 Niclosamide Inhibits Cell Growth and Enhances Drug Sensitivity of Hepatocellular Carcinoma Cells via STAT3 Signaling Pathway. 2018 3
31 28367059 Niclosamide inhibition of STAT3 synergizes with erlotinib in human colon cancer. 2017 4
32 28877265 Niclosamide induces protein ubiquitination and inhibits multiple pro-survival signaling pathways in the human glioblastoma U-87 MG cell line. 2017 1
33 29031202 Targeting of cell cycle and let-7a/STAT3 pathway by niclosamide inhibits proliferation, migration and invasion in oral squamous cell carcinoma cells. 2017 Dec 4
34 26792726 Niclosamide suppresses RANKL-induced osteoclastogenesis and prevents LPS-induced bone loss. 2016 Feb 5 1
35 27449264 WSTF promotes proliferation and invasion of lung cancer cells by inducing EMT via PI3K/Akt and IL-6/STAT3 signaling pathways. 2016 Nov 2
36 27545321 Defined Host-Guest Chemistry on Nanocarbon for Sustained Inhibition of Cancer. 2016 Nov 1
37 27793003 Evaluation of quantitative assays for the identification of direct signal transducer and activator of transcription 3 (STAT3) inhibitors. 2016 Nov 22 1
38 27888804 Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer. 2016 Dec 27 1
39 25970160 Niclosamide suppresses cell migration and invasion in enzalutamide resistant prostate cancer cells via Stat3-AR axis inhibition. 2015 Sep 4
40 26434865 Bevacizumab Regulates Cancer Cell Migration by Activation of STAT3. 2015 1
41 26716739 [Molecular mechanisms of niclosamide antitumor activity]. 2015 Nov-Dec 1
42 24362463 Disruption of STAT3 by niclosamide reverses radioresistance of human lung cancer. 2014 Mar 4
43 24732808 Multi-targeted therapy of cancer by niclosamide: A new application for an old drug. 2014 Jul 10 1
44 24945434 STAT3 modulation to enhance motor neuron differentiation in human neural stem cells. 2014 2
45 23459613 Discovery of O-Alkylamino Tethered Niclosamide Derivatives as Potent and Orally Bioavailable Anticancer Agents. 2013 Feb 14 1
46 23894143 Niclosamide overcomes acquired resistance to erlotinib through suppression of STAT3 in non-small cell lung cancer. 2013 Oct 2
47 24019973 Inhibition of STAT3 by niclosamide synergizes with erlotinib against head and neck cancer. 2013 4
48 22237038 Niclosamide, an old antihelminthic agent, demonstrates antitumor activity by blocking multiple signaling pathways of cancer stem cells. 2012 Apr 1
49 22829072 Redeployment-based drug screening identifies the anti-helminthic niclosamide as anti-myeloma therapy that also reduces free light chain production. 2011 Oct 1
50 24900231 Identification of Niclosamide as a New Small-Molecule Inhibitor of the STAT3 Signaling Pathway. 2010 Dec 9 2