Fatty Acids

peroxisome proliferative activated receptor, gamma, coactivator 1 alpha ; Mus musculus







77 Article(s)
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1 35051422 Effect of l-carnitine and mildronate on the mitochondrial metabolism of heart and bacterial composition of the gut microbiome in ageing mice. 2022 Mar 15 1
2 35401831 Hepatic PRMT1 ameliorates diet-induced hepatic steatosis via induction of PGC1α. 2022 1
3 35597365 Rho-associated, coiled-coil-containing protein kinase 1 regulates development of diabetic kidney disease via modulation of fatty acid metabolism. 2022 May 18 1
4 33446719 NT-PGC-1α deficiency attenuates high-fat diet-induced obesity by modulating food intake, fecal fat excretion and intestinal fat absorption. 2021 Jan 14 3
5 33473326 Adeno-associated virus-mediated delivery of anti-miR-199a tough decoys attenuates cardiac hypertrophy by targeting PGC-1alpha. 2021 Mar 5 1
6 34066911 Effects of Simvastatin on Lipid Metabolism in Wild-Type Mice and Mice with Muscle PGC-1α Overexpression. 2021 May 7 2
7 34073834 P2Y2R Deficiency Ameliorates Hepatic Steatosis by Reducing Lipogenesis and Enhancing Fatty Acid β-Oxidation through AMPK and PGC-1α Induction in High-Fat Diet-Fed Mice. 2021 May 24 1
8 34096010 Measuring PGC-1α and Its Acetylation Status in Mouse Primary Myotubes. 2021 2
9 34444756 Reduced Liver-Specific PGC1a Increases Susceptibility for Short-Term Diet-Induced Weight Gain in Male Mice. 2021 Jul 28 1
10 34581257 Prenatal stress promotes insulin resistance without inflammation or obesity in C57BL/6J male mice. 2021 Nov 1
11 34899332 Ferruginol Restores SIRT1-PGC-1α-Mediated Mitochondrial Biogenesis and Fatty Acid Oxidation for the Treatment of DOX-Induced Cardiotoxicity. 2021 1
12 31451071 PGC-1α activator-induced fatty acid oxidation in tumor-infiltrating CTLs enhances effects of PD-1 blockade therapy in lung cancer. 2020 Feb 1
13 31734944 Berberine protects against diabetic kidney disease via promoting PGC-1α-regulated mitochondrial energy homeostasis. 2020 Aug 2
14 31955265 Exchange protein directly activated by cAMP (Epac) 1 plays an essential role in stress-induced exercise capacity by regulating PGC-1α and fatty acid metabolism in skeletal muscle. 2020 Feb 2
15 32043636 REDD1 deficiency protects against nonalcoholic hepatic steatosis induced by high-fat diet. 2020 Apr 1
16 32060774 Protective Effects of PGC-1α on the Blood Brain Barrier After Acute Kidney Injury. 2020 May 1
17 32317752 Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1α PARylation in db/db mice. 2020 Aug 1
18 32452329 Co-Administration of Soluble Fibres and Lactobacillus casei NCDC19 Fermented Milk Prevents Adiposity and Insulin Resistance Via Modulation of Lipid Mobilization Genes in Diet-Induced Obese Mice. 2020 1
19 32733634 SOCS2 Inhibits Mitochondrial Fatty Acid Oxidation via Suppressing LepR/JAK2/AMPK Signaling Pathway in Mouse Adipocytes. 2020 1
20 32966981 Increased Insulin Sensitivity by High-Altitude Hypoxia in Mice with High-Fat Diet-Induced Obesity Is Associated with Activated AMPK Signaling and Subsequently Enhanced Mitochondrial Biogenesis in Skeletal Muscles. 2020 1
21 33115498 LncRNAH19 improves insulin resistance in skeletal muscle by regulating heterogeneous nuclear ribonucleoprotein A1. 2020 Oct 28 1
22 29931052 Heart specific PGC-1α deletion identifies metabolome of cardiac restricted metabolic heart failure. 2019 Jan 1 1
23 30876865 4-O-methylhonokiol ameliorates type 2 diabetes-induced nephropathy in mice likely by activation of AMPK-mediated fatty acid oxidation and Nrf2-mediated anti-oxidative stress. 2019 May 1 1
24 31393858 Dual peroxisome-proliferator-activated-receptor-α/γ activation inhibits SIRT1-PGC1α axis and causes cardiac dysfunction. 2019 Aug 8 2
25 31658614 Inducible Cardiac-Specific Deletion of Sirt1 in Male Mice Reveals Progressive Cardiac Dysfunction and Sensitization of the Heart to Pressure Overload. 2019 Oct 10 2
26 28540526 High-fat diet inhibits PGC-1α suppressive effect on NFκB signaling in hepatocytes. 2018 Aug 2
27 28724797 Increasing the level of peroxisome proliferator-activated receptor γ coactivator-1α in podocytes results in collapsing glomerulopathy. 2017 Jul 20 1
28 28751525 PGC-1α Protects from Notch-Induced Kidney Fibrosis Development. 2017 Nov 2
29 29104506 Skeletal Muscle-Specific Overexpression of PGC-1α Induces Fiber-Type Conversion through Enhanced Mitochondrial Respiration and Fatty Acid Oxidation in Mice and Pigs. 2017 3
30 29176803 Root bark of Ulmus davidiana var. japonica restrains acute alcohol-induced hepatic steatosis onset in mice by inhibiting ROS accumulation. 2017 1
31 26822083 PGC-1α Coordinates Mitochondrial Respiratory Capacity and Muscular Fatty Acid Uptake via Regulation of VEGF-B. 2016 Apr 1
32 26950361 A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance. 2016 Apr 7
33 27454177 Regulation of Brown and White Adipocyte Transcriptome by the Transcriptional Coactivator NT-PGC-1α. 2016 4
34 28721265 Molecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism. 2016 1
35 25308487 Measuring PGC-1α and its acetylation status in mouse primary myotubes. 2015 1
36 25554947 Mulberry and mulberry wine extract increase the number of mitochondria during brown adipogenesis. 2015 Feb 1
37 25774553 Naringenin prevents obesity, hepatic steatosis, and glucose intolerance in male mice independent of fibroblast growth factor 21. 2015 Jun 2
38 25893813 Rosiglitazone, but not epigallocatechin-3-gallate, attenuates the decrease in PGC-1α protein levels in palmitate-induced insulin-resistant C2C12 cells. 2015 Jun 1
39 26114427 Metabolomic Analysis of the Skeletal Muscle of Mice Overexpressing PGC-1α. 2015 1
40 26176781 OM2, a Novel Oligomannuronate-Chromium(III) Complex, Promotes Mitochondrial Biogenesis and Lipid Metabolism in 3T3-L1 Adipocytes via the AMPK-PGC1α Pathway. 2015 1
41 24458359 Cdc2-like kinase 2 suppresses hepatic fatty acid oxidation and ketogenesis through disruption of the PGC-1α and MED1 complex. 2014 May 3
42 24743151 Apolipoprotein O is mitochondrial and promotes lipotoxicity in heart. 2014 May 1
43 24776744 Maintaining PGC-1α expression following pressure overload-induced cardiac hypertrophy preserves angiogenesis but not contractile or mitochondrial function. 2014 Aug 1
44 24848065 NT-PGC-1α activation attenuates high-fat diet-induced obesity by enhancing brown fat thermogenesis and adipose tissue oxidative metabolism. 2014 Nov 2
45 23555678 Supplementation of Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 in diet-induced obese mice is associated with gut microbial changes and reduction in obesity. 2013 1
46 23787969 Hepatic-specific lipin-1 deficiency exacerbates experimental alcohol-induced steatohepatitis in mice. 2013 Dec 1
47 24069029 Temporal clustering of gene expression links the metabolic transcription factor HNF4α to the ER stress-dependent gene regulatory network. 2013 1
48 22446876 Improvement of myocardial lipid accumulation and prevention of PGC-1α induction by fenofibrate. 2012 Jun 1
49 22967499 Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice. 2012 Nov 15 1
50 21300801 Ncb5or deficiency increases fatty acid catabolism and oxidative stress. 2011 Apr 1 1