Arachidonic Acid

prostaglandin-endoperoxide synthase 2 ; Rattus norvegicus







41 Article(s)
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1 35172004 Metabolic Profiling Implicates a Critical Role of Cyclooxygenase-2-Mediated Arachidonic Acid Metabolism in Radiation-Induced Esophageal Injury in Rats. 2022 May 1 3
2 33645090 [Mechanism of Danggui Sini Decoction in treatment of primary dysmenorrhea based on network pharmacology and molecular docking]. 2021 Feb 1
3 32559618 Research on the mechanism of Chinese herbal medicine Radix Paeoniae Rubra in improving chronic pelvic inflammation disease by regulating PTGS2 in the arachidonic acid pathway. 2020 Sep 2
4 33339104 Protective Effect of Antioxidants in Nitric Oxide/COX-2 Interaction during Inflammatory Pain: The Role of Nitration. 2020 Dec 16 2
5 31244108 Engineered Substrate for Cyclooxygenase-2: A Pentapeptide Isoconformational to Arachidonic Acid for Managing Inflammation. 2019 Jul 11 1
6 28522561 Immediate and delayed potentiating effects of tumor necrosis factor-α on TRPV1 sensitivity of rat vagal pulmonary sensory neurons. 2017 Aug 1 1
7 25061885 Inhibition of endocannabinoid metabolism by the metabolites of ibuprofen and flurbiprofen. 2014 1
8 25339102 Organotypical vascular model for characterization of radioprotective compounds: studies on antioxidant 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors. 2014 2
9 23661609 A novel function for CUGBP2 in controlling the pro-inflammatory stimulus in H9c2 cells: subcellular trafficking of messenger molecules. 2013 Oct 2
10 21873648 SO(2)-induced neurotoxicity is mediated by cyclooxygenases-2-derived prostaglandin E(2) and its downstream signaling pathway in rat hippocampal neurons. 2011 Dec 1
11 19660237 Effect of COX-2 inhibitor meloxicam against traumatic brain injury-induced biochemical, histopathological changes and blood-brain barrier permeability. 2010 Jul 2
12 20956003 Enhanced cyclooxygenase 2-mediated vasorelaxation in coronary arteries from insulin-resistant obese Zucker rats. 2010 Dec 1
13 19371577 Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition. 2009 Apr 3
14 19884440 Pharmacological inhibition of 5-lipoxygenase accelerates and enhances fracture-healing. 2009 Nov 1
15 18554636 Intraprostatic botulinum toxin a injection inhibits cyclooxygenase-2 expression and suppresses prostatic pain on capsaicin induced prostatitis model in rat. 2008 Aug 1
16 17613692 Effects of the COX-2 inhibitor FK3311 on ischemia - reperfusion injury in the rat lung. 2007 May-Jun 1
17 17910482 Cyclooxygenase-2-mediated metabolism of arachidonic acid to 15-oxo-eicosatetraenoic acid by rat intestinal epithelial cells. 2007 Nov 2
18 16712820 Oxidation and cytotoxicity of 6-OHDA are mediated by reactive intermediates of COX-2 overexpressed in PC12 cells. 2006 Jun 6 1
19 15312159 Arachidonic acid-induced carbon-centered radicals and phospholipid peroxidation in cyclo-oxygenase-2-transfected PC12 cells. 2004 Sep 1
20 12604095 A role for COX-2 and p38 mitogen activated protein kinase in long-term depression in the rat dentate gyrus in vitro. 2003 Mar 2
21 12618123 Hippocampal kindling epileptogenesis upregulates neuronal cyclooxygenase-2 expression in neocortex. 2003 Feb 1
22 12900435 Role of COX-2 in the enhanced vasoconstrictor effect of arachidonic acid in the diabetic rat kidney. 2003 Oct 2
23 11966528 Inhibition of proliferation of gastric epithelial cells by a cyclooxygenase 2 inhibitor, JTE522, is also mediated by a PGE2-independent pathway. 2002 Apr 2
24 12090811 Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder? 2002 Jul 1
25 12369737 DOI, an agonist of 5-HT2A/2C serotonin receptor, alters the expression of cyclooxygenase-2 in the rat parietal cortex. 2002 Sep 1
26 11368948 Inducible cyclooxygenase-2 expression after experimental intracerebral hemorrhage. 2001 May 18 2
27 11487305 Stimulated release of arachidonic acid from rat liver cells by celecoxib and indomethacin. 2001 Jul 2
28 10734171 Signal transduction cascade in staurosporine-induced prostaglandin E(2) production by rat peritoneal macrophages. 2000 Apr 3
29 10972245 Prolonged cyclooxygenase-2 induction in neurons and glia following traumatic brain injury in the rat. 2000 Aug 2
30 11113602 5-Lipoxygenase and cyclooxygenase mRNA expression in rat hippocampus:early response to glutamate receptor activation by kainate. 2000 Dec 2
31 11118808 Unilateral upregulation of cyclooxygenase-2 following cerebral, cortical photothrombosis in the rat: suppression by MK-801 and co-distribution with enzymes involved in the oxidative stress cascade. 2000 Nov 2
32 9748570 Cyclooxygenase 2 mRNA expression in rat brain after peripheral injection of lipopolysaccharide. 1998 Aug 17 2
33 9789085 Pharmacological analysis of cyclooxygenase-1 in inflammation. 1998 Oct 27 1
34 9057838 Expression and regulation of cyclooxygenase-2 in rat microglia. 1997 Feb 1 2
35 9163569 Dual effects of auranofin on prostaglandin E2 production by rat peritoneal macrophages. 1997 May 1 1
36 9014225 Effects of non-steroidal anti-inflammatory drugs on prostaglandin E2 production by cyclooxygenase-2 from endogenous and exogenous arachidonic acid in rat peritoneal macrophages stimulated with lipopolysaccharide. 1996 Dec 1
37 7782073 Cytosolic phospholipase A2 gene in human and rat: chromosomal localization and polymorphic markers. 1995 Mar 1 2
38 8521479 Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. 1995 Nov 3 3
39 9064608 Induction of cyclooxygenase-2 mRNA and protein following transient focal ischemia in the rat brain. 1995 Nov 24 1
40 8077206 Endothelin stimulates prostaglandin endoperoxide synthase-2 mRNA expression and protein synthesis through a tyrosine kinase-signaling pathway in rat mesangial cells. 1994 Sep 9 1
41 7916614 Cloning and expression of rat prostaglandin endoperoxide synthase (cyclooxygenase)-2 cDNA. 1993 Dec 15 1