Guanosine Diphosphate

RAN, member RAS oncogene family ; Homo sapiens







61 Article(s)
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Pub. Year
#Total Relationships
1 33912945 On the asymmetric partitioning of nucleocytoplasmic transport - recent insights and open questions. 2021 Apr 1 2
2 32528950 Ran GTPase: A Key Player in Tumor Progression and Metastasis. 2020 1
3 31484720 REV7 has a dynamic adaptor region to accommodate small GTPase RAN/Shigella IpaB ligands, and its activity is regulated by the RanGTP/GDP switch. 2019 Oct 25 3
4 29040603 Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation. 2018 Feb 1 1
5 26124124 Small GTP-binding protein Ran is regulated by posttranslational lysine acetylation. 2015 Jul 14 2
6 26304119 MYCBP2 Is a Guanosine Exchange Factor for Ran Protein and Determines Its Localization in Neurons of Dorsal Root Ganglia. 2015 Oct 16 1
7 24563355 Ran GTPase in nuclear envelope formation and cancer metastasis. 2014 1
8 23160023 Downregulation of the small GTPase ras-related nuclear protein accelerates cellular ageing. 2013 Mar 1
9 23536659 Guanine-nucleotide exchange factor RCC1 facilitates a tight binding between the encephalomyocarditis virus leader and cellular Ran GTPase. 2013 Jun 1
10 23878195 Interaction of transportin-SR2 with Ras-related nuclear protein (Ran) GTPase. 2013 Aug 30 1
11 22880006 Nuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation. 2012 1
12 25436539 Small GTPase Ran and Ran-binding proteins. 2012 Aug 3
13 20609434 Tyr39 of ran preserves the Ran.GTP gradient by inhibiting GTP hydrolysis. 2010 Aug 6 4
14 20300488 RanGTPase: A Key Regulator of Nucleocytoplasmic Trafficking. 2009 2
15 18469014 The RanGTP gradient - a GPS for the mitotic spindle. 2008 May 15 2
16 18565325 ARA24/Ran enhances the androgen-dependent NH2- and COOH-terminal interaction of the androgen receptor. 2008 Aug 29 2
17 18708071 Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics. 2008 Nov 21 2
18 17433702 Biochemical characterization of a family of proteins that stabilizes a plant Ran protein in its GTP-bound conformation. 2007 Jun-Jul 7
19 15807788 Plant-specific mitotic targeting of RanGAP requires a functional WPP domain. 2005 Apr 4
20 16248653 Common semiopen conformations of Mg2+-free Ras, Rho, Rab, Arf, and Ran proteins combined with GDP and their similarity with GEF-bound forms. 2005 Nov 2 1
21 15155737 An ATP-dependent activity that releases RanGDP from NTF2. 2004 Aug 27 1
22 15351280 Purification of RanGDP, RanGTP, and RanGMPPNP by ion exchange chromatography. 2004 Oct 1 2
23 15454457 Direct discrimination between models of protein activation by single-molecule force measurements. 2004 Oct 1
24 11911364 Both ran and importins have the ability to function as nuclear mRNA export factors. 2002 Feb 2
25 11932251 Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor. 2002 May 17 10
26 12034733 Fluorescence resonance energy transfer biosensors that detect Ran conformational changes and a Ran x GDP-importin-beta -RanBP1 complex in vitro and in intact cells. 2002 Aug 16 2
27 12194828 Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells. 2002 Aug 20 1
28 11231159 Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system. 2001 Feb 6 3
29 10679025 Monoclonal antibodies to NTF2 inhibit nuclear protein import by preventing nuclear translocation of the GTPase Ran. 2000 Feb 1
30 10995230 Different structural and kinetic requirements for the interaction of Ran with the Ran-binding domains from RanBP2 and importin-beta. 2000 Sep 26 1
31 11029654 Nucleocytoplasmic protein traffic and its significance to cell function. 2000 Oct 1
32 11099382 Crystal structures of a Rab protein in its inactive and active conformations. 2000 Dec 8 1
33 10369786 Model of the ran-RCC1 interaction using biochemical and docking experiments. 1999 Jun 18 1
34 9510255 The 1.7 A crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller. 1998 Mar 5 2
35 9533885 Structural basis for molecular recognition between nuclear transport factor 2 (NTF2) and the GDP-bound form of the Ras-family GTPase Ran. 1998 Apr 3 3
36 9640542 Functions of the GTPase Ran in RNA export from the nucleus. 1998 Jun 1
37 9843686 Nuclear transport factor p10/NTF2 functions as a Ran-GDP dissociation inhibitor (Ran-GDI). 1998 Dec 3 9
38 9857054 Ran-dependent signal-mediated nuclear import does not require GTP hydrolysis by Ran. 1998 Dec 25 1
39 9878368 The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2). 1998 Dec 18 6
40 9889103 Nuclear import of Ran is mediated by the transport factor NTF2. 1998 Dec 17-31 2
41 9121474 Yrb2p, a Nup2p-related yeast protein, has a functional overlap with Rna1p, a yeast Ran-GTPase-activating protein. 1997 Apr 6
42 9201707 Functional domains in nuclear import factor p97 for binding the nuclear localization sequence receptor and the nuclear pore. 1997 Jun 2
43 9261173 High levels of the GTPase Ran/TC4 relieve the requirement for nuclear protein transport factor 2. 1997 Aug 22 2
44 9315840 Dynamic and equilibrium studies on the interaction of Ran with its effector, RanBP1. 1997 Oct 7 2
45 9398678 A T42A Ran mutation: differential interactions with effectors and regulators, and defect in nuclear protein import. 1997 Dec 2
46 8655589 Evidence using a green fluorescent protein-glucocorticoid receptor chimera that the Ran/TC4 GTPase mediates an essential function independent of nuclear protein import. 1996 Jun 1
47 8682210 Protein import into the nucleus. 1996 Jun 24 1
48 8755535 Nucleotide-specific interaction of Ran/TC4 with nuclear transport factors NTF2 and p97. 1996 Jul 23 7
49 8889801 RCC1 in the Ran pathway. 1996 Aug 2
50 8909533 RanBP1 stabilizes the interaction of Ran with p97 nuclear protein import. 1996 Nov 5