lactacystin

caspase 3 ; Homo sapiens







12 Article(s)
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1 21683092 Neuroprotective effects of MAPK/ERK1/2 and calpain inhibitors on lactacystin-induced cell damage in primary cortical neurons. 2011 Dec 1
2 18298651 Proteasome inhibitor-induced apoptosis is mediated by positive feedback amplification of PKCdelta proteolytic activation and mitochondrial translocation. 2008 Dec 2
3 18800014 c-Jun N-terminal kinase mediates lactacystin-induced dopamine neuron degeneration. 2008 Oct 1
4 17396132 Endoplasmic reticulum stress-induced cell death mediated by the proteasome. 2007 Jun 1
5 16337881 Oxidative stress response results in increased p21WAF1/CIP1 degradation in cystic fibrosis lung epithelial cells. 2006 Jan 1 1
6 16857313 PTEN is recruited to specific microdomains of the plasma membrane during lactacystin-induced neuronal apoptosis. 2006 Sep 11 1
7 15265709 p38 MAPK mediates TNF-induced apoptosis in endothelial cells via phosphorylation and downregulation of Bcl-x(L). 2004 Aug 15 1
8 15492836 Proteasomes act in the pre-mitochondrial signal transduction route towards roscovitine-induced apoptosis. 2004 Nov 1
9 12869638 Preservation of caspase-3 subunits from degradation contributes to apoptosis evoked by lactacystin: any single lysine or lysine pair of the small subunit is sufficient for ubiquitination. 2003 Aug 5
10 11319608 Pro-caspase-3 overexpression sensitises ovarian cancer cells to proteasome inhibitors. 2001 Mar 1
11 10229667 Inhibition of ubiquitin-proteasome pathway activates a caspase-3-like protease and induces Bcl-2 cleavage in human M-07e leukaemic cells. 1999 May 15 1
12 8694836 Enhancement of CPP32-like activity in the TNF-treated U937 cells by the proteasome inhibitors. 1996 Jul 5 1