Arsenic

nuclear factor, erythroid derived 2, like 2 ; Mus musculus







34 Article(s)
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1 35210942 Arsenic Induces Continuous Inflammation and Regulates Th1/Th2/Th17/Treg Balance in Liver and Kidney In Vivo. 2022 1
2 35313999 Lentinan alleviates arsenic-induced hepatotoxicity in mice via downregulation of OX40/IL-17A and activation of Nrf2 signaling. 2022 Mar 22 1
3 35523338 Nrf2 activation contributes to hepatic tumor-augmenting effects of developmental arsenic exposure. 2022 Sep 1 8
4 33242462 Chlorogenic acid abates male reproductive dysfunction in arsenic-exposed mice via attenuation of testicular oxido-inflammatory stress and apoptotic responses. 2021 Jan 5 1
5 33410021 Therapeutic effects of biochanin A, phloretin, and epigallocatechin-3-gallate in reducing oxidative stress in arsenic-intoxicated mice. 2021 Apr 1
6 33884178 Sodium arsenite induces spatial learning and memory impairment associated with oxidative stress and activates the Nrf2/PPARγ pathway against oxidative injury in mice hippocampus. 2021 Mar 1
7 33933676 Non-canonical NRF2 activation promotes a pro-diabetic shift in hepatic glucose metabolism. 2021 Sep 1
8 34272803 Curcumin functions as an anti-inflammatory and antioxidant agent on arsenic-induced hepatic and kidney injury by inhibiting MAPKs/NF-κB and activating Nrf2 pathways. 2021 Nov 2
9 34516406 Astrocyte-derived exosomes protect hippocampal neurons after traumatic brain injury by suppressing mitochondrial oxidative stress and apoptosis. 2021 Sep 13 1
10 32760496 Chronic arsenic exposure induces the time-dependent modulation of inflammation and immunosuppression in spleen. 2020 1
11 32871193 A strategy for repression of arsenic toxicity through nuclear factor E2 related factor 2 activation mediated by the (E)-2-alkenals in Coriandrum sativum L. leaf extract. 2020 Nov 1
12 30357758 The Variable Regulatory Effect of Arsenic on Nrf2 Signaling Pathway in Mouse: a Systematic Review and Meta-analysis. 2019 Aug 7
13 30503583 Ellagic and ferulic acids protect arsenic-induced male reproductive toxicity via regulating Nfe2l2, Ppargc1a and StAR expressions in testis. 2019 Feb 1 1
14 30742845 Nrf2 deficiency aggravates the increase in osteoclastogenesis and bone loss induced by inorganic arsenic. 2019 Mar 15 9
15 27978490 Acute arsenic exposure induces inflammatory responses and CD4+ T cell subpopulations differentiation in spleen and thymus with the involvement of MAPK, NF-kB, and Nrf2. 2017 Jan 2
16 28125038 Arsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin Cancer. 2017 Jan 24 2
17 28549828 Deficiency of long isoforms of Nfe2l1 sensitizes MIN6 pancreatic β cells to arsenite-induced cytotoxicity. 2017 Aug 15 1
18 28843991 Imbalanced immune responses involving inflammatory molecules and immune-related pathways in the lung of acute and subchronic arsenic-exposed mice. 2017 Nov 2
19 29108910 Effects of Nrf2 deficiency on arsenic metabolism in mice. 2017 Dec 15 10
20 26187899 Lutein alleviates arsenic-induced reproductive toxicity in male mice via Nrf2 signaling. 2016 May 1
21 25092181 High accumulation of arsenic in the esophagus of mice after exposure to arsenite. 2015 Oct 1
22 25680285 Nrf2-dependent repression of interleukin-12 expression in human dendritic cells exposed to inorganic arsenic. 2015 Nov 1
23 25815309 Lutein has a protective effect on hepatotoxicity induced by arsenic via Nrf2 signaling. 2015 1
24 26371860 Activation of NRF2 pathway in spleen, thymus as well as peripheral blood mononuclear cells by acute arsenic exposure in mice. 2015 Oct 7
25 26473898 Hepatic and Nephric NRF2 Pathway Up-Regulation, an Early Antioxidant Response, in Acute Arsenic-Exposed Mice. 2015 Oct 12 3
26 23766851 Nrf2 protection against liver injury produced by various hepatotoxicants. 2013 1
27 23871787 Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion. 2013 Sep 2
28 27335833 In Vivo Effect of Arsenic Trioxide on Keap1-p62-Nrf2 Signaling Pathway in Mouse Liver: Expression of Antioxidant Responsive Element-Driven Genes Related to Glutathione Metabolism. 2013 1
29 22488045 Arsenic modulates heme oxygenase-1, interleukin-6, and vascular endothelial growth factor expression in endothelial cells: roles of ROS, NF-κB, and MAPK pathways. 2012 Jun 3
30 22975029 Sulforaphane prevents pulmonary damage in response to inhaled arsenic by activating the Nrf2-defense response. 2012 Dec 15 1
31 23000044 Deficiency in the nuclear factor E2-related factor 2 renders pancreatic β-cells vulnerable to arsenic-induced cell damage. 2012 Nov 1 1
32 19808700 Critical cysteine residues of Kelch-like ECH-associated protein 1 in arsenic sensing and suppression of nuclear factor erythroid 2-related factor 2. 2010 Jan 7
33 19538980 Nrf2 protects against As(III)-induced damage in mouse liver and bladder. 2009 Oct 1 4
34 16516206 Sulforaphane, an activator of Nrf2, suppresses cellular accumulation of arsenic and its cytotoxicity in primary mouse hepatocytes. 2006 Mar 20 1