sulforaphane

NFE2 like bZIP transcription factor 2 ; Homo sapiens







282 Article(s)
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1 33079284 Sulforaphane Induces Glioprotection After LPS Challenge. 2022 Apr 2
2 35041848 Sulforaphane improves cognitive dysfunction after surgery and anesthesia in mice: The role of Keap1-Nrf2 signaling. 2022 Apr 2
3 35179529 Biphasic effect of sulforaphane on angiogenesis in hypoxia via modulation of both Nrf2 and mitochondrial dynamics. 2022 Mar 7 2
4 35327653 The Impact of NRF2 Inhibition on Drug-Induced Colon Cancer Cell Death and p53 Activity: A Pilot Study. 2022 Mar 17 2
5 35370554 Sulforaphane Ameliorates Metabolic Changes Associated With Status Epilepticus in Immature Rats. 2022 2
6 35512617 Breast cancer susceptibility gene 1 regulates oxidative damage via nuclear factor erythroid 2-related factor 2 in oral cancer cells. 2022 Jul 4
7 35563167 Targeting Sirt1, AMPK, Nrf2, CK2, and Soluble Guanylate Cyclase with Nutraceuticals: A Practical Strategy for Preserving Bone Mass. 2022 Apr 26 1
8 31409554 The isothiocyanate sulforaphane inhibits mTOR in an NRF2-independent manner. 2021 Jun 2
9 31721705 In Silico Drug-designing Studies on Sulforaphane Analogues: Pharmacophore Mapping, Molecular Docking and QSAR Modeling. 2021 2
10 32281399 The Potential for Reducing Lynch Syndrome Cancer Risk with Nutritional Nrf2 Activators. 2021 1
11 32762135 Cabbage and fermented vegetables: From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19. 2021 Mar 1
12 33064289 R-sulforaphane modulates the expression profile of AhR, ERα, Nrf2, NQO1, and GSTP in human breast cell lines. 2021 Feb 2
13 33126057 The NRF2-LOC344887 signaling axis suppresses pulmonary fibrosis. 2021 Jan 2
14 33160067 The phytoprotective agent sulforaphane prevents inflammatory degenerative diseases and age-related pathologies via Nrf2-mediated hormesis. 2021 Jan 1
15 33338213 Cruciferous vegetables: rationale for exploring potential salutary effects of sulforaphane-rich foods in patients with chronic kidney disease. 2021 Oct 11 2
16 33388347 Sulforaphane ameliorates ethanol plus carbon tetrachloride-induced liver fibrosis in mice through the Nrf2-mediated antioxidant response and acetaldehyde metabolization with inhibition of the LPS/TLR4 signaling pathway. 2021 Mar 3
17 33392911 The Isothiocyanate Sulforaphane Depends on the Nrf2/γ-GCL/GSH Axis to Prevent Mitochondrial Dysfunction in Cells Exposed to Methylglyoxal. 2021 Apr 1
18 33477669 Eat Your Broccoli: Oxidative Stress, NRF2, and Sulforaphane in Chronic Kidney Disease. 2021 Jan 18 1
19 33488795 Sulforaphane protects human umbilical vein endothelial cells from oxidative stress via the miR-34a/SIRT1 axis by upregulating nuclear factor erythroid-2-related factor 2. 2021 Mar 1
20 33498683 Activation of Nrf2 by Electrophiles Is Largely Independent of the Selenium Status of HepG2 Cells. 2021 Jan 23 1
21 33805772 Pre-Clinical Neuroprotective Evidences and Plausible Mechanisms of Sulforaphane in Alzheimer's Disease. 2021 Mar 13 2
22 33814512 Arsenite induces tissue factor synthesis through Nrf2 activation in cultured human aortic smooth muscle cells. 2021 2
23 33892113 Nrf2 inhibition sensitizes breast cancer stem cells to ionizing radiation via suppressing DNA repair. 2021 Jun 1
24 33894213 Sulforaphane inhibits blue light-induced inflammation and apoptosis by upregulating the SIRT1/PGC-1α/Nrf2 pathway and autophagy in retinal pigment epithelial cells. 2021 Jun 15 7
25 33899586 Nrf2-Keap-1 imbalance under acute shear stress induces inflammatory response in venous endothelial cells. 2021 Apr 25 1
26 34094831 Inhibiting autophagy enhances sulforaphane-induced apoptosis via targeting NRF2 in esophageal squamous cell carcinoma. 2021 May 1
27 34112534 Inhibition of Nrf2-mediated glucose metabolism by brusatol synergistically sensitizes acute myeloid leukemia to Ara-C. 2021 Oct 2
28 34119834 Structure-based molecular hybridization design of Keap1-Nrf2 inhibitors as novel protective agents of acute lung injury. 2021 Oct 15 3
29 34153466 Sulforaphane improves mitochondrial metabolism in fibroblasts from patients with fragile X-associated tremor and ataxia syndrome. 2021 Sep 2
30 34205320 Elevation of Chemosensitivity of Lung Adenocarcinoma A549 Spheroid Cells by Claudin-2 Knockdown through Activation of Glucose Transport and Inhibition of Nrf2 Signal. 2021 Jun 19 2
31 34316328 Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis. 2021 Jul 20 4
32 34411187 Correction: The anti-arthritis effect of sulforaphane, an activator of Nrf2, is associated with inhibition of both B cell differentiation and the production of inflammatory cytokines. 2021 1
33 34443505 The Inhibitory Effect of Sulforaphane on Bladder Cancer Cell Depends on GSH Depletion-Induced by Nrf2 Translocation. 2021 Aug 13 6
34 34455814 GSTM1 Gene, Diet, and Kidney Disease: Implication for Precision Medicine?: Recent Advances in Hypertension. 2021 Sep 1
35 34583226 Targeting Nrf2/Keap1 signaling pathway by bioactive natural agents: Possible therapeutic strategy to combat liver disease. 2021 Nov 1
36 34678578 The protective effect of sulforaphane against oxidative stress in granulosa cells of patients with polycystic ovary syndrome (PCOS) through activation of AMPK/AKT/NRF2 signaling pathway. 2021 Dec 6
37 34767876 Molecular mechanisms of hepatotoxic cholestasis by clavulanic acid: Role of NRF2 and FXR pathways. 2021 Dec 1
38 34772403 Nestin is essential for cellular redox homeostasis and gastric cancer metastasis through the mediation of the Keap1-Nrf2 axis. 2021 Nov 12 1
39 34927380 Effect of a sulforaphane supplement on muscle soreness and damage induced by eccentric exercise in young adults: A pilot study. 2021 Dec 3
40 34939763 The Protective Effect of Sulforaphane against Oxidative Stress through Activation of NRF2/ARE Pathway in Human Granulosa Cells. 2021 Nov 3
41 34942962 Bioactive Compounds in Oxidative Stress-Mediated Diseases: Targeting the NRF2/ARE Signaling Pathway and Epigenetic Regulation. 2021 Nov 23 1
42 34942977 Murine Neonatal Oxidant Lung Injury: NRF2-Dependent Predisposition to Adulthood Respiratory Viral Infection and Protection by Maternal Antioxidant. 2021 Nov 24 1
43 31784171 Emerging promise of sulforaphane-mediated Nrf2 signaling cascade against neurological disorders. 2020 Mar 10 4
44 31838078 Melatonin-sulforaphane hybrid ITH12674 attenuates glial response in vivo by blocking LPS binding to MD2 and receptor oligomerization. 2020 Feb 1
45 31884317 Differential regulation of Nrf2 is linked to elevated inflammation and nitrative stress in monocytes of children with autism. 2020 Mar 3
46 31918259 Transcription factor NRF2 uses the Hippo pathway effector TAZ to induce tumorigenesis in glioblastomas. 2020 Feb 1
47 31945311 A cell-based assay system for activators of the environmental cell stress response. 2020 Mar 1 1
48 32017935 Targeting Keap1/Nrf2/ARE signaling pathway in multiple sclerosis. 2020 Apr 15 1
49 32061629 Transcriptional activation of antioxidant gene expression by Nrf2 protects against mitochondrial dysfunction and neuronal death associated with acute and chronic neurodegeneration. 2020 Jun 1
50 32108526 Sulforaphane prevents right ventricular injury and reduces pulmonary vascular remodeling in pulmonary arterial hypertension. 2020 Apr 1 2