Sorafenib

NFE2 like bZIP transcription factor 2 ; Homo sapiens







19 Article(s)
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1 35380342 CRISPR-Cas9-based genome-wide screening identified novel targets for treating sorafenib-resistant hepatocellular carcinoma: a cross-talk between FGF21 and the NRF2 pathway. 2022 Apr 1 2
2 35592903 Implications of Withaferin A for the metastatic potential and drug resistance in hepatocellular carcinoma cells via Nrf2-mediated EMT and ferroptosis. 2022 May 19 1
3 33770521 Quiescin sulfhydryl oxidase 1 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by driving EGFR endosomal trafficking and inhibiting NRF2 activation. 2021 May 2
4 34159680 The BAFF/NFκB axis is crucial to interactions between sorafenib-resistant HCC cells and cancer-associated fibroblasts. 2021 Sep 1
5 34473785 Nrf2 signaling promotes cancer stemness, migration, and expression of ABC transporter genes in sorafenib-resistant hepatocellular carcinoma cells. 2021 6
6 34482117 Overcoming the compensatory elevation of NRF2 renders hepatocellular carcinoma cells more vulnerable to disulfiram/copper-induced ferroptosis. 2021 Oct 2
7 34530350 SIRT6 silencing overcomes resistance to sorafenib by promoting ferroptosis in gastric cancer. 2021 Nov 5 2
8 34768109 ABCC5 facilitates the acquired resistance of sorafenib through the inhibition of SLC7A11-induced ferroptosis in hepatocellular carcinoma. 2021 Dec 1
9 31367013 SLC27A5 deficiency activates NRF2/TXNRD1 pathway by increased lipid peroxidation in HCC. 2020 Mar 1
10 32304346 An Artemisinin-Derivative-(NHC)Gold(I) Hybrid with Enhanced Cytotoxicity through Inhibition of NRF2 Transcriptional Activity. 2020 Jul 13 1
11 32388267 Downregulation of thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cancer. 2020 Jul 2
12 32560747 Programmed Death Ligand-1 (PD-L1) Regulated by NRF-2/MicroRNA-1 Regulatory Axis Enhances Drug Resistance and Promotes Tumorigenic Properties in Sorafenib-Resistant Hepatoma Cells. 2020 Dec 10 4
13 30647407 Activation of c-Met in cancer cells mediates growth-promoting signals against oxidative stress through Nrf2-HO-1. 2019 Jan 15 2
14 29061583 Bioengineered NRF2-siRNA Is Effective to Interfere with NRF2 Pathways and Improve Chemosensitivity of Human Cancer Cells. 2018 Jan 2
15 26403645 Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells. 2016 Jan 3
16 27015352 Metallothionein-1G facilitates sorafenib resistance through inhibition of ferroptosis. 2016 Aug 1
17 27184800 Metallothionein-1 as a biomarker of altered redox metabolism in hepatocellular carcinoma cells exposed to sorafenib. 2016 May 16 1
18 23314856 The noncytotoxic dose of sorafenib sensitizes Bel-7402/5-FU cells to 5-FU by down-regulating 5-FU-induced Nrf2 expression. 2013 Jun 4
19 20428777 Sorafenib with doxorubicin augments cytotoxicity to renal cell cancer through PERK inhibition. 2010 Jun 3