Fluorouracil

NFE2 like bZIP transcription factor 2 ; Homo sapiens







32 Article(s)
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1 34264023 HO-1 in lymph node metastasis predicted overall survival in patients with esophageal squamous cell carcinoma receiving neoadjuvant chemoradiation therapy. 2022 Mar 1
2 33511942 Current Perspectives on the Role of Nrf2 in 5-Fluorouracil Resistance in Colorectal Cancer. 2021 8
3 33838628 Upregulation of NOX-2 and Nrf-2 Promotes 5-Fluorouracil Resistance of Human Colon Carcinoma (HCT-116) Cells. 2021 Mar 3
4 34485154 Angelica Polysaccharide Antagonizes 5-FU-Induced Oxidative Stress Injury to Reduce Apoptosis in the Liver Through Nrf2 Pathway. 2021 6
5 34575034 Dexamethasone Sensitizes Cancer Stem Cells to Gemcitabine and 5-Fluorouracil by Increasing Reactive Oxygen Species Production through NRF2 Reduction. 2021 Aug 27 1
6 31811910 FoxO3 reverses 5-fluorouracil resistance in human colorectal cancer cells by inhibiting the Nrf2/TR1 signaling pathway. 2020 Feb 1 3
7 31938994 iASPP-Mediated ROS Inhibition Drives 5-Fu Resistance Dependent on Nrf2 Antioxidative Signaling Pathway in Gastric Adenocarcinoma. 2020 Oct 3
8 32629871 NRF2 Knockdown Resensitizes 5-Fluorouracil-Resistant Pancreatic Cancer Cells by Suppressing HO-1 and ABCG2 Expression. 2020 Jun 30 3
9 30473361 Drug screening assay based on the interaction of intact Keap1 and Nrf2 proteins in cancer cells. 2019 Jan 1 3
10 30993753 Identification of Nrf2/STAT3 axis in induction of apoptosis through sub-G 1 cell cycle arrest mechanism in HT-29 colon cancer cells. 2019 Aug 1
11 31293646 Nuclear Nrf2 Activity in Laryngeal Carcinoma is Regulated by SENP3 After Cisplatin-Induced Reactive Oxygen Species Stress. 2019 2
12 31298161 Role of Nuclear Factor Erythroid 2-Related Factor 2 (NRF-2) Mediated Antioxidant Response on the Synergistic Antitumor Effect of L-Arginine and 5-Fluro Uracil (5FU) in Breast Adenocarcinoma. 2019 3
13 31911862 RV-59 suppresses cytoplasmic Nrf2-mediated 5-fluorouracil resistance and tumor growth in colorectal cancer. 2019 1
14 28962868 Chemopreventive effects of FITOPROT against 5-fluorouracil-induced toxicity in HaCaT cells. 2018 Jan 15 1
15 29899863 PSMD4 is a novel therapeutic target in chemoresistant colorectal cancer activated by cytoplasmic localization of Nrf2. 2018 May 29 1
16 29902094 Suppression of NRF2/ARE by convallatoxin sensitises A549 cells to 5-FU-mediated apoptosis. 2018 Dec 1
17 30119680 lncRNA KRAL reverses 5-fluorouracil resistance in hepatocellular carcinoma cells by acting as a ceRNA against miR-141. 2018 Aug 17 3
18 28671577 Silencing of NRF2 Reduces the Expression of ALDH1A1 and ALDH3A1 and Sensitizes to 5-FU in Pancreatic Cancer Cells. 2017 Jul 1 3
19 27015836 Nrf2 inhibition sensitizes cholangiocarcinoma cells to cytotoxic and antiproliferative activities of chemotherapeutic agents. 2016 Aug 1
20 27259240 Interaction of DNA demethylase and histone methyltransferase upregulates Nrf2 in 5-fluorouracil-resistant colon cancer cells. 2016 Jun 28 4
21 25588809 Clinicopathological significance of nuclear factor (erythroid-2)-related factor 2 (Nrf2) expression in gastric cancer. 2015 Jan 15 1
22 25625649 γ-Tocotrienol prevents 5-FU-induced reactive oxygen species production in human oral keratinocytes through the stabilization of 5-FU-induced activation of Nrf2. 2015 Apr 6
23 25708948 Repression of Nrf2 enhances antitumor effect of 5-fluorouracil and gemcitabine on cholangiocarcinoma cells. 2015 Jun 2
24 25896253 MiR-141 Activates Nrf2-Dependent Antioxidant Pathway via Down-Regulating the Expression of Keap1 Conferring the Resistance of Hepatocellular Carcinoma Cells to 5-Fluorouracil. 2015 3
25 26410168 Correlation Between Nuclear Factor E2-Related Factor 2 Expression and Gastric Cancer Progression. 2015 Sep 27 2
26 26622665 Promoter demethylation of nuclear factor-erythroid 2-related factor 2 gene in drug-resistant colon cancer cells. 2015 Sep 2
27 24743738 Epigenetic modification of Nrf2 in 5-fluorouracil-resistant colon cancer cells: involvement of TET-dependent DNA demethylation. 2014 Apr 17 6
28 23314856 The noncytotoxic dose of sorafenib sensitizes Bel-7402/5-FU cells to 5-FU by down-regulating 5-FU-induced Nrf2 expression. 2013 Jun 18
29 24175806 Nrf2 overexpression predicts prognosis and 5-FU resistance in gastric cancer. 2013 3
30 21969819 NRF2 mutation confers malignant potential and resistance to chemoradiation therapy in advanced esophageal squamous cancer. 2011 Sep 2
31 19524433 Involvement of Nrf2 activation in resistance to 5-fluorouracil in human colon cancer HT-29 cells. 2009 Aug 5
32 18692501 Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer. 2008 Oct 4