Arsenic

NFE2 like bZIP transcription factor 2 ; Homo sapiens







67 Article(s)
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1 34798141 Corrigendum to "Nrf2 deficiency aggravates the increase in osteoclastogenesis and bone loss induced by inorganic arsenic" [Toxicology and applied pharmacology 367 (2019) 62-70]. 2022 Jan 15 1
2 33261869 Sustained high expression of NRF2 and its target genes induces dysregulation of cellular proliferation and apoptosis is associated with arsenite-induced malignant transformation of human bronchial epithelial cells. 2021 Feb 20 2
3 33434570 Differential effects of arsenic species on Nrf2 and Bach1 nuclear localization in cultured hepatocytes. 2021 Feb 15 13
4 33552384 Retracted: Proanthocyanidins Antagonize Arsenic-Induced Oxidative Damage and Promote Arsenic Methylation through Activation of the Nrf2 Signaling Pathway. 2021 1
5 33823236 Cooperation between NRF2-mediated transcription and MDIG-dependent epigenetic modifications in arsenic-induced carcinogenesis and cancer stem cells. 2021 Nov 2
6 34959015 Arsenic causes mitochondrial biogenesis obstacles by inhibiting the AMPK/PGC-1α signaling pathway and also induces apoptosis and dysregulated mitophagy in the duck liver. 2021 Dec 24 1
7 32226544 Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells. 2020 1
8 32682831 Chronic arsenic exposure enhances metastatic potential via NRF2-mediated upregulation of SOX9. 2020 Sep 1 2
9 32802886 A Systematic Review of the Various Effect of Arsenic on Glutathione Synthesis In Vitro and In Vivo. 2020 1
10 32971865 Arsenic Methyltransferase and Methylation of Inorganic Arsenic. 2020 Sep 22 1
11 33178028 Ursodeoxycholic Acid Protects Against Arsenic Induced Hepatotoxicity by the Nrf2 Signaling Pathway. 2020 2
12 30738023 Daphnetin activates the Nrf2-dependent antioxidant response to prevent arsenic-induced oxidative insult in human lung epithelial cells. 2019 Apr 1 3
13 30769048 Mangiferin alleviates arsenic induced oxidative lung injury via upregulation of the Nrf2-HO1 axis. 2019 Apr 1
14 30805085 Proanthocyanidins Antagonize Arsenic-Induced Oxidative Damage and Promote Arsenic Methylation through Activation of the Nrf2 Signaling Pathway. 2019 2
15 30878179 Oncogenic role of arsenic exposure in lung cancer: A forgotten risk factor. 2019 Jul 1
16 31139082 Pterostilbene Activates the Nrf2-Dependent Antioxidant Response to Ameliorate Arsenic-Induced Intracellular Damage and Apoptosis in Human Keratinocytes. 2019 3
17 31345348 Prenatal exposure to metals modified DNA methylation and the expression of antioxidant- and DNA defense-related genes in newborns in an urban area. 2019 Sep 1
18 31445708 Botrysphin D attenuates arsenic-induced oxidative stress in human lung epithelial cells via activating Nrf2/ARE signaling pathways. 2019 Oct 20 1
19 31781319 Enhanced p62-NRF2 Feedback Loop due to Impaired Autophagic Flux Contributes to Arsenic-Induced Malignant Transformation of Human Keratinocytes. 2019 1
20 29247444 Effect of Arsenic Exposure on NRF2-KEAP1 Pathway and Epigenetic Modification. 2018 Sep 2
21 30291177 Withdrawal: Antioncogenic and oncogenic properties of Nrf2 in arsenic-induced carcinogenesis. 2018 Oct 5 1
22 28125038 Arsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin Cancer. 2017 Jan 24 2
23 28229933 Nuclear lamins and progerin are dispensable for antioxidant Nrf2 response to arsenic and cadmium. 2017 May 3
24 28625800 Arsenic alters transcriptional responses to Pseudomonas aeruginosa infection and decreases antimicrobial defense of human airway epithelial cells. 2017 Sep 15 1
25 29029432 The involvement of Nrf2 in the protective effects of (-)-Epigallocatechin-3-gallate (EGCG) on NaAsO2-induced hepatotoxicity. 2017 Sep 12 2
26 29051854 An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress. 2017 Oct 1
27 29081891 NRF2 Is a Potential Modulator of Hyperresistance to Arsenic Toxicity in Stem-Like Keratinocytes. 2017 1
28 26404762 2,3,5,6-Tetramethylpyrazine (TMP) down-regulated arsenic-induced heme oxygenase-1 and ARS2 expression by inhibiting Nrf2, NF-κB, AP-1 and MAPK pathways in human proximal tubular cells. 2016 Sep 3
29 26791102 miR-214 protects erythroid cells against oxidative stress by targeting ATF4 and EZH2. 2016 Mar 2
30 26878773 Antioxidant tert-butylhydroquinone ameliorates arsenic-induced intracellular damages and apoptosis through induction of Nrf2-dependent antioxidant responses as well as stabilization of anti-apoptotic factor Bcl-2 in human keratinocytes. 2016 May 2
31 27317373 Nrf2 activation ameliorates cytotoxic effects of arsenic trioxide in acute promyelocytic leukemia cells through increased glutathione levels and arsenic efflux from cells. 2016 Aug 15 2
32 25680285 Nrf2-dependent repression of interleukin-12 expression in human dendritic cells exposed to inorganic arsenic. 2015 Nov 7
33 25752797 Characterization of arsenic hepatobiliary transport using sandwich-cultured human hepatocytes. 2015 Jun 1
34 26385919 Antioncogenic and Oncogenic Properties of Nrf2 in Arsenic-induced Carcinogenesis. 2015 Nov 6 1
35 26535918 NADPH Oxidase-Dependent Mechanism Explains How Arsenic and Other Oxidants Can Activate Aryl Hydrocarbon Receptor Signaling. 2015 Dec 21 1
36 24107458 Nuclear factor erythroid 2-related factor gene variants and susceptibility of arsenic-related skin lesions. 2014 Jun 2
37 24161444 Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms. 2014 Feb 2
38 24516582 The NRF2-KEAP1 pathway is an early responsive gene network in arsenic exposed lymphoblastoid cells. 2014 1
39 24632381 Nrf2 expression and activity in human T lymphocytes: stimulation by T cell receptor activation and priming by inorganic arsenic and tert-butylhydroquinone. 2014 Jun 2
40 24970285 Tert-butylhydroquinone as a phenolic activator of Nrf2 antagonizes arsenic-induced oxidative cytotoxicity but promotes arsenic methylation and detoxication in human hepatocyte cell line. 2014 Aug 3
41 25201354 Induction of glutathione synthesis in human hepatocytes by acute and chronic arsenic exposure: differential roles of mitogen-activated protein kinases. 2014 Nov 5 4
42 21809430 Sodium arsenite induced reactive oxygen species generation, nuclear factor (erythroid-2 related) factor 2 activation, heme oxygenase-1 expression, and glutathione elevation in Chang human hepatocytes. 2013 Jul 6
43 22914984 Nrf2-mediated redox signaling in arsenic carcinogenesis: a review. 2013 Feb 2
44 23069314 A semi-mechanistic integrated toxicokinetic-toxicodynamic (TK/TD) model for arsenic(III) in hepatocytes. 2013 Jan 21 1
45 23188707 Arsenic-mediated activation of the Nrf2-Keap1 antioxidant pathway. 2013 Feb 8
46 23589329 Arsenic inhibits autophagic flux, activating the Nrf2-Keap1 pathway in a p62-dependent manner. 2013 Jun 5
47 23710286 Curcumin protects human keratinocytes against inorganic arsenite-induced acute cytotoxicity through an NRF2-dependent mechanism. 2013 1
48 23738048 Activation of the Nrf2 pathway by inorganic arsenic in human hepatocytes and the role of transcriptional repressor Bach1. 2013 8
49 22155346 Opposite effects of arsenic trioxide on the Nrf2 pathway in oral squamous cell carcinoma in vitro and in vivo. 2012 May 1 2
50 22476201 Cross-regulations among NRFs and KEAP1 and effects of their silencing on arsenic-induced antioxidant response and cytotoxicity in human keratinocytes. 2012 Apr 2