Serine

mitogen-activated protein kinase 3 ; Homo sapiens







194 Article(s)
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1 35460012 Berberine Improves TNF-α-Induced Hepatic Insulin Resistance by Targeting MEKK1/MEK Pathway. 2022 Apr 22 1
2 32762307 Serine 897 Phosphorylation of EPHA2 Is Involved in Signaling of Oncogenic ERK1/2 Drivers in Thyroid Cancer Cells. 2021 Jan 1
3 32804243 PDCD4 limits prooncogenic neuregulin-ErbB signaling. 2021 Feb 1
4 33000894 Role of serine 365 in BRAF V600E sensitivity to RAF inhibition. 2021 Jul 1
5 33582914 Knockdown of Microtubule Associated Serine/threonine Kinase Like Expression Inhibits Gastric Cancer Cell Growth and Induces Apoptosis by Activation of ERK1/2 and Inactivation of NF-κB Signaling. 2021 Feb 1
6 33895117 PDGF-BB-mediated activation of CREB in vascular smooth muscle cells alters cell cycling via Rb, FoxO1 and p27kip1. 2021 Jul 1 1
7 34265398 Phosphorylation of intestine-specific homeobox by ERK1 modulates oncogenic activity and sorafenib resistance. 2021 Nov 1 1
8 34564169 RSK1 vs. RSK2 Inhibitory Activity of the Marine β-Carboline Alkaloid Manzamine A: A Biochemical, Cervical Cancer Protein Expression, and Computational Study. 2021 Sep 7 1
9 31917333 Δ9-tetrahydrocannabinol and 2-AG decreases neurite outgrowth and differentially affects ERK1/2 and Akt signaling in hiPSC-derived cortical neurons. 2020 Mar 1
10 32170114 Phosphoproteomics identifies a bimodal EPHA2 receptor switch that promotes embryonic stem cell differentiation. 2020 Mar 13 1
11 32183046 Vaccarin Regulates Diabetic Chronic Wound Healing through FOXP2/AGGF1 Pathways. 2020 Mar 13 1
12 32296771 Differential Role of Serines and Threonines in Intracellular Loop 3 and C-Terminal Tail of the Histamine H4 Receptor in β-Arrestin and G Protein-Coupled Receptor Kinase Interaction, Internalization, and Signaling. 2020 Apr 10 1
13 32989218 Extracellular signal-regulated kinases associate with and phosphorylate DHPS to promote cell proliferation. 2020 Sep 28 2
14 30711252 Extracellular signal-regulated kinase-1 phosphorylates early growth response-1 at serine 26. 2019 Mar 12 1
15 30794926 Targeting ERK1/2 protein-serine/threonine kinases in human cancers. 2019 Apr 2
16 30819803 The RING domain in the anti-apoptotic protein XIAP stabilizes c-Myc protein and preserves anchorage-independent growth of bladder cancer cells. 2019 Apr 12 1
17 30912166 Dephosphorylation-induced EZH2 activation mediated RECK downregulation by ERK1/2 signaling. 2019 Aug 1
18 30962349 ERK1/2 phosphorylates HIF-2α and regulates its activity by controlling its CRM1-dependent nuclear shuttling. 2019 Apr 8 2
19 30986276 Role of β-adrenergic signaling in masseter muscle. 2019 1
20 31013829 Crosstalk between p38 and Erk 1/2 in Downregulation of FGF1-Induced Signaling. 2019 Apr 12 1
21 31146385 Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 Pathway. 2019 May 29 4
22 31308216 SRC and ERK cooperatively phosphorylate DLC1 and attenuate its Rho-GAP and tumor suppressor functions. 2019 Sep 2 1
23 31352445 Fibroblast Growth Factors: A Controlling Mechanism of Skin Aging. 2019 2
24 29242151 Resveratrol induces sumoylated COX-2-dependent anti-proliferation in human prostate cancer LNCaP cells. 2018 Feb 1
25 29405768 Diepoxybutane-induced apoptosis is mediated through the ERK1/2 pathway. 2018 Oct 1
26 29454706 GATA6 phosphorylation by Erk1/2 propels exit from pluripotency and commitment to primitive endoderm. 2018 Apr 1 1
27 29945223 The effect of the DISC1 Ser704Cys polymorphism on striatal dopamine synthesis capacity: an [18F]-DOPA PET study. 2018 Oct 15 1
28 30380514 The fungal metabolite cyclonerodiol inhibits IL-4/IL-13 induced Stat6-signaling through blocking the association of Stat6 with p38, ERK1/2 and p300. 2018 Dec 1
29 30430306 The Role of Extracellular Signal-Regulated Kinases (ERK) in the Regulation of mGlu5 Receptors in Neurons. 2018 Dec 1
30 30527445 Enzymatic Phosphorylation of Ser in a Type I Collagen Peptide. 2018 Dec 18 2
31 28099845 Absence of Neurofibromin Induces an Oncogenic Metabolic Switch via Mitochondrial ERK-Mediated Phosphorylation of the Chaperone TRAP1. 2017 Jan 17 1
32 28279977 AKT-phosphorylated FOXO1 suppresses ERK activation and chemoresistance by disrupting IQGAP1-MAPK interaction. 2017 Apr 13 1
33 28365441 The multi-site docking protein Gab1 is constitutively phosphorylated independent from its recruitment to the plasma membrane in Jak2-V617F-positive cells and mediates proliferation of human erythroleukaemia cells. 2017 Jul 1
34 28393288 Differential effects of p38 MAP kinase inhibitors SB203580 and SB202190 on growth and migration of human MDA-MB-231 cancer cell line. 2017 Aug 2
35 28542650 Interdependence of JAK-STAT and MAPK signaling pathways during EGF-mediated HTR-8/SVneo cell invasion. 2017 1
36 28801242 Oxidant species are involved in T/B-mediated ERK1/2 phosphorylation that activates p53-p21 axis to promote KSHV lytic cycle in PEL cells. 2017 Nov 1
37 28847747 Hypoxia induced phosphorylation of estrogen receptor at serine 118 in the absence of ligand. 2017 Nov 2
38 26346493 Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome. 2016 Feb 1
39 26615958 Biomechanical insult switches PEA-15 activity to uncouple its anti-apoptotic function and promote erk mediated tissue remodeling. 2016 Jan 15 1
40 27086924 ERK1/2-induced phosphorylation of R-Ras GTPases stimulates their oncogenic potential. 2016 Oct 27 1
41 27094035 Insulin-induced cytokine production in macrophages causes insulin resistance in hepatocytes. 2016 Jun 1 1
42 27181361 PAX5 tyrosine phosphorylation by SYK co-operatively functions with its serine phosphorylation to cancel the PAX5-dependent repression of BLIMP1: A mechanism for antigen-triggered plasma cell differentiation. 2016 Jun 24 1
43 27366950 ERK1/2/MAPK pathway-dependent regulation of the telomeric factor TRF2. 2016 Jul 19 1
44 27452456 mRNA Cap Methylation in Pluripotency and Differentiation. 2016 Aug 2 1
45 27470585 RKIP phosphorylation-dependent ERK1 activation stimulates adipogenic lipid accumulation in 3T3-L1 preadipocytes overexpressing LC3. 2016 Sep 9 1
46 27559307 Synaptic GluN2B/CaMKII-α Signaling Induces Synapto-Nuclear Transport of ERK and Jacob. 2016 1
47 27793200 Subcellular localisation of pMEK has a different prognosis in locally advanced head and neck cancer treated with concomitant radiochemotherapy. 2016 Oct 28 1
48 25447552 STIM1 phosphorylation triggered by epidermal growth factor mediates cell migration. 2015 Jan 1
49 25569096 Human adipose tissue conditioned media from lean subjects is protective against H2O2 induced neurotoxicity in human SH-SY5Y neuronal cells. 2015 Jan 6 1
50 25584415 Serine-727 phosphorylation activates hypothalamic STAT-3 independently from tyrosine-705 phosphorylation. 2015 Mar 2