Phorbol Esters

mitogen-activated protein kinase 3 ; Homo sapiens







38 Article(s)
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1 30012864 Ribosomal RACK1:Protein Kinase C βII Modulates Intramolecular Interactions between Unstructured Regions of Eukaryotic Initiation Factor 4G (eIF4G) That Control eIF4E and eIF3 Binding. 2018 Oct 1 1
2 23987506 Hierarchical scaffolding of an ERK1/2 activation pathway. 2013 Aug 29 2
3 22230807 Increased expression and phosphorylation of the two S100A9 isoforms in mononuclear cells from patients with systemic lupus erythematosus: a proteomic signature for circulating low-density granulocytes. 2012 Mar 16 1
4 21665893 A protein kinase C/protein kinase D pathway protects LNCaP prostate cancer cells from phorbol ester-induced apoptosis by promoting ERK1/2 and NF-{kappa}B activities. 2011 Aug 1
5 20392800 RasGRP1 stimulation enhances ubiquitination and endocytosis of the sodium-chloride cotransporter. 2010 Aug 2
6 20433920 HIV-1 Tat-peptide inhibits protein kinase C and protein kinase A through substrate competition. 2010 Aug 11 1
7 19004007 Genomic instability and histone H3 phosphorylation induction by the Ras-mitogen activated protein kinase pathway in pancreatic cancer cells. 2009 Feb 1 1
8 18029162 Activation of p38 and JNK MAPK pathways abrogates requirement for new protein synthesis for phorbol ester mediated induction of select MMP and TIMP genes. 2008 Mar 1
9 18534741 Activation of PKC epsilon induces lactotroph proliferation through ERK1/2 in response to phorbol ester. 2008 Jul 16 1
10 17404058 Jaceosidin, a pharmacologically active flavone derived from Artemisia argyi, inhibits phorbol-ester-induced upregulation of COX-2 and MMP-9 by blocking phosphorylation of ERK-1 and -2 in cultured human mammary epithelial cells. 2007 Jan 1
11 17404064 Peonidin inhibits phorbol-ester-induced COX-2 expression and transformation in JB6 P+ cells by blocking phosphorylation of ERK-1 and -2. 2007 Jan 1
12 16582936 Regulation of ERK1/2 activity by ghrelin-activated growth hormone secretagogue receptor 1A involves a PLC/PKCvarepsilon pathway. 2006 Jun 1
13 16973759 A delayed gonadotropin-dependent and growth factor-mediated activation of the extracellular signal-regulated kinase 1/2 cascade negatively regulates aromatase expression in granulosa cells. 2006 Dec 2
14 15677375 PKC-delta-dependent pathways contribute to PDGF-stimulated ERK1/2 activation in vascular smooth muscle. 2005 Jun 1
15 15721302 Phorbol ester phorbol-12-myristate-13-acetate promotes anchorage-independent growth and survival of melanomas through MEK-independent activation of ERK1/2. 2005 Apr 1 1
16 15737652 RasGRP3 mediates phorbol ester-induced, protein kinase C-independent exocytosis. 2005 Apr 8 1
17 15851572 Acute effects of PGF2alpha on MMP-2 secretion from human ciliary muscle cells: a PKC- and ERK-dependent process. 2005 May 1
18 16356124 Curcumin inhibits phorbol ester-induced up-regulation of cyclooxygenase-2 and matrix metalloproteinase-9 by blocking ERK1/2 phosphorylation and NF-kappaB transcriptional activity in MCF10A human breast epithelial cells. 2005 Nov-Dec 1
19 14739659 Resveratrol antagonizes EGFR-dependent Erk1/2 activation in human androgen-independent prostate cancer cells with associated isozyme-selective PKC alpha inhibition. 2004 Apr 1
20 15023352 A kinetic approach towards understanding substrate interactions and the catalytic mechanism of the serine/threonine protein kinase ERK2: identifying a potential regulatory role for divalent magnesium. 2004 Mar 11 1
21 15542774 Inhibitory effect of epidermal growth factor on resveratrol-induced apoptosis in prostate cancer cells is mediated by protein kinase C-alpha. 2004 Nov 1
22 12783880 Regulation of ERK1 and ERK2 by glucose and peptide hormones in pancreatic beta cells. 2003 Aug 29 1
23 19649217 Role of mitogen-activated protein kinase in cardiac hypertrophy and heart failure. 2003 Winter 1
24 11781135 Activation of Erk1/Erk2 and transiently increased p53 levels together may account for p21 expression associated with phorbol ester-induced transient growth inhibition in HepG2 cells. 2002 Feb 1
25 12134900 Modulation of phorbol ester-induced regulation of matrix metalloproteinases and tissue inhibitors of metalloproteinases by SB203580, a specific inhibitor of p38 mitogen-activated protein kinase. 2002 Jul 1
26 12433834 Phorbol ester induction of angiotensin-converting enzyme transcription is mediated by Egr-1 and AP-1 in human endothelial cells via ERK1/2 pathway. 2002 Nov 15 1
27 12492114 Mitogen-activated protein kinase routes as targets in the action of diaza-anthracene compounds with a potent growth-inhibitory effect on cancer cells. 2002 Aug 1
28 11169731 Activation of extracellular signal-regulated kinases (ERKs) defines the first phase of 1,25-dihydroxyvitamin D3-induced differentiation of HL60 cells. 2001 1
29 11259586 p38 mitogen-activated protein kinase-dependent activation of protein phosphatases 1 and 2A inhibits MEK1 and MEK2 activity and collagenase 1 (MMP-1) gene expression. 2001 Apr 2
30 11422447 Antiproliferative properties of sphingosine-1-phosphate in human hepatic myofibroblasts. 2001 Jun 2
31 11707282 A PKCbeta isoform mediates phorbol ester-induced activation of Erk1/2 and expression of neuronal differentiation genes in neuroblastoma cells. 2001 Nov 9 1
32 10506137 Adaptive increase of amino acid transport system A requires ERK1/2 activation. 1999 Oct 8 1
33 9990315 Thrombopoietin potentiates the protein-kinase-C-mediated activation of mitogen-activated protein kinase/ERK kinases and extracellular signal-regulated kinases in human platelets. 1998 Dec 15 1
34 9277481 Protein kinase C-dependent regulation of the human AT1 promoter in vascular smooth muscle cells. 1997 Aug 1
35 8663194 Big mitogen-activated protein kinase 1 (BMK1) is a redox-sensitive kinase. 1996 Jul 12 1
36 8761473 Inhibition of mitogen-activated protein kinase kinase does not impair primary activation of human platelets. 1996 Aug 15 1
37 8119929 Interleukin-4-dependent proliferation dissociates p44erk-1, p42erk-2, and p21ras activation from cell growth. 1994 Feb 25 1
38 1518847 Phorbol ester stimulates a protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product. 1992 Sep 1 2