Phenytoin

nuclear receptor subfamily 1 group I member 2 ; Homo sapiens







9 Article(s)
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1 35062050 CYP450 drug inducibility in NAFLD via an in vitro hepatic model: Understanding drug-drug interactions in the fatty liver. 2022 Feb 2
2 27713827 Evaluation of a novel PXR-knockout in HepaRG cells. 2016 Oct 1
3 26516577 Applicability of second-generation upcyte® human hepatocytes for use in CYP inhibition and induction studies. 2015 Oct 1
4 19855097 CYP2C9*1B promoter polymorphisms, in linkage with CYP2C19*2, affect phenytoin autoinduction of clearance and maintenance dose. 2010 Feb 1
5 18606396 Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor. 2009 Feb 15 1
6 18332078 Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction. 2008 Jun 1
7 15849716 Modulation of UDP-glucuronosyltransferase 1A1 in primary human hepatocytes by prototypical inducers. 2005 1
8 12695351 Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes. 2003 May 1
9 12065438 CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes. 2002 Jul 1