Curcumin

AKT serine/threonine kinase 1 ; Rattus norvegicus







56 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34980778 Coadministration of Curcumin and Hydromorphone Hydrochloride Alleviates Postoperative Pain in Rats. 2022 1
2 35122926 Neuroprotective effects of curcumin via autophagy induction in 6-hydroxydopamine Parkinson's models. 2022 May 5
3 31162984 Curcumin promotes functional recovery and inhibits neuronal apoptosis after spinal cord injury through the modulation of autophagy. 2021 Jan 2
4 33354908 Curcumin attenuates renal interstitial fibrosis by regulating autophagy and retaining mitochondrial function in unilateral ureteral obstruction rats. 2021 Apr 1
5 34103964 Curcumin-Alleviated Osteoarthritic Progression in Rats Fed a High-Fat Diet by Inhibiting Apoptosis and Activating Autophagy via Modulation of MicroRNA-34a. 2021 3
6 34284543 Curcumin promotes the proliferation, invasion of neural stem cells and formation of neurospheres via activating SDF-1/CXCR4 axis. 2021 1
7 34463926 Curcumin Sensitizes Prolactinoma Cells to Bromocriptine by Activating the ERK/EGR1 and Inhibiting the AKT/GSK-3β Signaling Pathway In Vitro and In Vivo. 2021 Dec 1
8 34497845 Curcumin Improves Pulmonary Hypertension Rats by Regulating Mitochondrial Function. 2021 1
9 34533799 Mechanism of curcumin against myocardial ischaemia-reperfusion injury based on the P13K/Akt/mTOR signalling pathway. 2021 Sep 4
10 34555398 Cardio-protective effect of tetrahydrocurcumin, the primary hydrogenated metabolite of curcumin in vivo and in vitro: Induction of apoptosis and autophagy via PI3K/AKT/mTOR pathways. 2021 Nov 15 1
11 34577062 Curcumin and Nano-Curcumin Mitigate Copper Neurotoxicity by Modulating Oxidative Stress, Inflammation, and Akt/GSK-3β Signaling. 2021 Sep 15 2
12 32464442 Curcumin alleviates arsenic-induced toxicity in PC12 cells via modulating autophagy/apoptosis. 2020 Sep 1 1
13 32830149 Curcumin targets vascular endothelial growth factor via activating the PI3K/Akt signaling pathway and improves brain hypoxic-ischemic injury in neonatal rats. 2020 Sep 1 3
14 32893562 [Study on mechanism of curcumin in treatment of acute pancreatitis based on regulation of PI3K-Akt signaling pathway by miR-198]. 2020 Aug 3
15 32961025 Curcumin alleviates oxidative stress and inhibits apoptosis in diabetic cardiomyopathy via Sirt1-Foxo1 and PI3K-Akt signalling pathways. 2020 Nov 3
16 33204708 Curcumin Improves the Renal Autophagy in Rat Experimental Membranous Nephropathy via Regulating the PI3K/AKT/mTOR and Nrf2/HO-1 Signaling Pathways. 2020 3
17 33536913 Curcumin Nanoparticle Enhances the Anticancer Effect of Cisplatin by Inhibiting PI3K/AKT and JAK/STAT3 Pathway in Rat Ovarian Carcinoma Induced by DMBA. 2020 1
18 33680047 Pharmacological Evidences for Curcumin Neuroprotective Effects against Lead-Induced Neurodegeneration: Possible Role of Akt/GSK3 Signaling Pathway. 2020 Summer 3
19 30551377 Curcumin pretreatment protects against hypoxia/reoxgenation injury via improvement of mitochondrial function, destabilization of HIF-1α and activation of Epac1-Akt pathway in rat bone marrow mesenchymal stem cells. 2019 Jan 4
20 31086728 A combination of curcumin, vorinostat and silibinin reverses Aβ-induced nerve cell toxicity via activation of AKT-MDM2-p53 pathway. 2019 1
21 31092832 Possible activation of NRF2 by Vitamin E/Curcumin against altered thyroid hormone induced oxidative stress via NFĸB/AKT/mTOR/KEAP1 signalling in rat heart. 2019 May 15 1
22 31694300 Curcumin Ameliorates Lead-Induced Hepatotoxicity by Suppressing Oxidative Stress and Inflammation, and Modulating Akt/GSK-3β Signaling Pathway. 2019 Nov 5 3
23 31741405 Curcumin alleviates diabetic nephropathy via inhibiting podocyte mesenchymal transdifferentiation and inducing autophagy in rats and MPC5 cells. 2019 Dec 4
24 31827700 Dietary Supplementation of the Antioxidant Curcumin Halts Systemic LPS-Induced Neuroinflammation-Associated Neurodegeneration and Memory/Synaptic Impairment via the JNK/NF-κB/Akt Signaling Pathway in Adult Rats. 2019 2
25 29052798 Curcumin pretreatment prevents hydrogen peroxide-induced oxidative stress through enhanced mitochondrial function and deactivation of Akt/Erk signaling pathways in rat bone marrow mesenchymal stem cells. 2018 Jun 3
26 29080256 Curcumin attenuates high glucose-induced inflammatory injury through the reactive oxygen species-phosphoinositide 3-kinase/protein kinase B-nuclear factor-κB signaling pathway in rat thoracic aorta endothelial cells. 2018 Jul 1
27 29243061 Neuroprotective Effect of Curcumin Against Cerebral Ischemia-Reperfusion Via Mediating Autophagy and Inflammation. 2018 Jan 2
28 29579407 Modulatory effect of curcumin on ketamine-induced toxicity in rat thymocytes: Involvement of reactive oxygen species (ROS) and the phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt) pathway. 2018 Nov 7 1
29 29677548 Combination of curcumin and vagus nerve stimulation attenuates cerebral ischemia/reperfusion injury-induced behavioral deficits. 2018 Jul 1
30 29715758 NGF and PI3K/Akt signaling participate in the ventral motor neuronal protection of curcumin in sciatic nerve injury rat models. 2018 Jul 5
31 29723552 PI3K/Akt/GSK3β induced CREB activation ameliorates arsenic mediated alterations in NMDA receptors and associated signaling in rat hippocampus: Neuroprotective role of curcumin. 2018 Jul 3
32 29938678 The effect of curcumin and PI3K/Akt inhibitor on monosodium glutamate-induced rat thymocytes toxicity. 2018 May 2
33 28429187 Curcumin reverses the depressive-like behavior and insulin resistance induced by chronic mild stress. 2017 Aug 1
34 28622711 Curcumin accelerates the repair of sciatic nerve injury in rats through reducing Schwann cells apoptosis and promoting myelinization. 2017 Aug 1
35 28860665 Effect of curcumin on glycerol-induced acute kidney injury in rats. 2017 Aug 31 1
36 29285156 Curcumin suppresses AGEs induced apoptosis in tubular epithelial cells via protective autophagy. 2017 Dec 1
37 29422835 Nanoparticle-Encapsulated Curcumin Inhibits Diabetic Neuropathic Pain Involving the P2Y12 Receptor in the Dorsal Root Ganglia. 2017 2
38 25432891 Strategy to Suppress Oxidative Damage-Induced Neurotoxicity in PC12 Cells by Curcumin: the Role of ROS-Mediated DNA Damage and the MAPK and AKT Pathways. 2016 Jan 1
39 26648392 Curcumin ameliorates dopaminergic neuronal oxidative damage via activation of the Akt/Nrf2 pathway. 2016 Feb 5
40 26989696 Curcumin Protects Neonatal Rat Cardiomyocytes against High Glucose-Induced Apoptosis via PI3K/Akt Signalling Pathway. 2016 3
41 27043868 New mechanism in the modulation of carbon tetrachloride hepatotoxicity in rats using different natural antioxidants. 2016 May 1
42 27551266 Benzo(a)pyrene Induced p53 Mediated Male Germ Cell Apoptosis: Synergistic Protective Effects of Curcumin and Resveratrol. 2016 1
43 25474544 Curcumin improves high glucose-induced INS-1 cell insulin resistance via activation of insulin signaling. 2015 Feb 2
44 25519685 Curcumin ameliorate DENA-induced HCC via modulating TGF-β, AKT, and caspase-3 expression in experimental rat model. 2015 Mar 2
45 25644785 Downregulation of PI3-K/Akt/PTEN pathway and activation of mitochondrial intrinsic apoptosis by Diclofenac and Curcumin in colon cancer. 2015 Apr 2
46 26074974 Pretreatment of Adipose Derived Stem Cells with Curcumin Facilitates Myocardial Recovery via Antiapoptosis and Angiogenesis. 2015 1
47 27122821 Curcumin Suppress Cardiac Fibroblasts Activities by Regulating Proliferation, Migration, and the Extracellular Matrix. 2014 Sep 2
48 23555802 Neuroprotection by curcumin in ischemic brain injury involves the Akt/Nrf2 pathway. 2013 4
49 23816368 The curry spice curcumin attenuates beta-amyloid-induced toxicity through beta-catenin and PI3K signaling in rat organotypic hippocampal slice culture. 2013 Oct 1
50 23954730 Free and nanoencapsulated curcumin suppress β-amyloid-induced cognitive impairments in rats: involvement of BDNF and Akt/GSK-3β signaling pathway. 2013 Nov 1