Serine

glycogen synthase kinase 3 alpha ; Homo sapiens







111 Article(s)
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1 32391926 Sorafenib induces pigmentation via the regulation of β-catenin signalling pathway in melanoma cells. 2022 Jan 1
2 34764205 The Protein Kinase Activity of NME7 Activates Wnt/β-Catenin Signaling to Promote One-Carbon Metabolism in Hepatocellular Carcinoma. 2022 Jan 1 1
3 35090098 Protein phosphatase 1 regulatory inhibitor subunit 14C promotes triple-negative breast cancer progression via sustaining inactive glycogen synthase kinase 3 beta. 2022 Jan 1
4 35347072 eEF2K promotes PD-L1 stabilization through inactivating GSK3β in melanoma. 2022 Mar 1
5 35390715 Development of inhibitors targeting glycogen synthase kinase-3β for human diseases: Strategies to improve selectivity. 2022 Jun 5 1
6 35402914 Malignant glioma subset from actuate 1801: Phase I/II study of 9-ING-41, GSK-3β inhibitor, monotherapy or combined with chemotherapy for refractory malignancies. 2022 Jan-Dec 1
7 35409221 Identification of Novel GSK-3β Hits Using Competitive Biophysical Assays. 2022 Mar 31 1
8 35568694 Mammalian eIF4E2-GSK3β maintains basal phosphorylation of p53 to resist senescence under hypoxia. 2022 May 14 1
9 35607451 Melatonin increases growth properties in human dermal papilla spheroids by activating AKT/GSK3β/β-Catenin signaling pathway. 2022 2
10 33030673 Tideglusib attenuates growth of neuroblastoma cancer stem/progenitor cells in vitro and in vivo by specifically targeting GSK-3β. 2021 Feb 1
11 33188146 FBW7 Inhibits Myeloid Differentiation in Acute Myeloid Leukemia via GSK3-Dependent Ubiquitination of PU.1. 2021 Feb 1
12 33309639 SCRT1 is a novel beta cell transcription factor with insulin regulatory properties. 2021 Feb 5 1
13 33327806 Novel oxindole/benzofuran hybrids as potential dual CDK2/GSK-3β inhibitors targeting breast cancer: design, synthesis, biological evaluation, and in silico studies. 2021 Dec 1
14 33414248 Placental Insulin/IGF-1 Signaling, PGC-1α, and Inflammatory Pathways Are Associated With Metabolic Outcomes at 4-6 Years of Age: The ECHO Healthy Start Cohort. 2021 Mar 1
15 33461462 Anti-inflammatory Potential of GSK-3 Inhibitors. 2021 5
16 33492962 Novel 18F-Labeled Isonicotinamide-Based Radioligands for Positron Emission Tomography Imaging of Glycogen Synthase Kinase-3β. 2021 Mar 1 1
17 33682722 Dysregulation of GSK3β-Target Proteins in Skin Fibroblasts of Myotonic Dystrophy Type 1 (DM1) Patients. 2021 1
18 33918222 Additional Inhibition of Wnt/β-Catenin Signaling by Metformin in DAA Treatments as a Novel Therapeutic Strategy for HCV-Infected Patients. 2021 Apr 2 1
19 33951093 GSK3ß inhibitor CHIR 99021 modulates cerebral organoid development through dose-dependent regulation of apoptosis, proliferation, differentiation and migration. 2021 1
20 34002210 ANXA1-GSK3β interaction and its involvement in NSCLC metastasis. 2021 Jul 5 1
21 34023818 Glycogen synthase kinase-3 beta (GSK3β)-mediated phosphorylation of ETS1 promotes progression of ovarian carcinoma. 2021 May 23 1
22 34162041 AGEs promote calcification of HASMCs by mediating Pi3k/AKT-GSK3β signaling. 2021 May 30 1
23 34198826 Glycogen Synthase Kinase 3 Beta Regulates the Human Aryl Hydrocarbon Receptor Cellular Content and Activity. 2021 Jun 5 1
24 34206370 Repurposing Niclosamide for Targeting Pancreatic Cancer by Inhibiting Hh/Gli Non-Canonical Axis of Gsk3β. 2021 Jun 22 1
25 34406791 Keratin 19 interacts with GSK3β to regulate its nuclear accumulation and degradation of cyclin D3. 2021 Nov 1 1
26 34461526 GSK3β as a novel promising target to overcome chemoresistance in pancreatic cancer. 2021 Sep 1
27 34569452 Screening of Azadirachta indica phytoconstituents as GSK-3β inhibitor and its implication in neuroblastoma: molecular docking, molecular dynamics, MM-PBSA binding energy, and in-vitro study. 2021 Sep 27 1
28 34589270 TAM-derived extracellular vesicles containing microRNA-29a-3p explain the deterioration of ovarian cancer. 2021 Sep 3 2
29 34732689 GSK-3β manipulates ferroptosis sensitivity by dominating iron homeostasis. 2021 Nov 3 1
30 34948382 GSK3β Serine 389 Phosphorylation Modulates Cardiomyocyte Hypertrophy and Ischemic Injury. 2021 Dec 18 4
31 34975828 GSK3β Interacts With CRMP2 and Notch1 and Controls T-Cell Motility. 2021 1
32 31785335 Emerging roles of GSK-3α in pathophysiology: Emphasis on cardio-metabolic disorders. 2020 Feb 1
33 31919413 GSK3β is a key regulator of the ROS-dependent necrotic death induced by the quinone DMNQ. 2020 Jan 2 1
34 32307979 Effects of Arsenic on wnt/β-catenin Signaling Pathway: A Systematic Review and Meta-analysis. 2020 Jun 15 1
35 32344182 Genetic mutational analysis of β-catenin gene affecting GSK-3β phosphorylation plays a role in gallbladder carcinogenesis: Results from a case control study. 2020 Apr 21 1
36 32395524 Dezocine regulates the malignant potential and aerobic glycolysis of liver cancer targeting Akt1/GSK-3β pathway. 2020 Apr 1
37 32425837 Novel Treatment Strategies Targeting Myelin and Oligodendrocyte Dysfunction in Schizophrenia. 2020 1
38 32470749 The mood stabilizing properties of AF3581, a novel potent GSK-3β inhibitor. 2020 Aug 14
39 32481626 Hypoxia-Induced miR-675-5p Supports β-Catenin Nuclear Localization by Regulating GSK3-β  Activity in Colorectal Cancer Cell Lines. 2020 May 28 1
40 32503133 Glycogen Synthase Kinase 3β in Cancer Biology and Treatment. 2020 Jun 3 3
41 32521784 Glycogen Synthase Kinase-3β Facilitates Cytokine Production in 12-O-Tetradecanoylphorbol-13-Acetate/Ionomycin-Activated Human CD4+ T Lymphocytes. 2020 Jun 8 1
42 32850361 The Role of GSK3β in T Lymphocytes in the Tumor Microenvironment. 2020 1
43 32855684 CD147 promotes epithelial-mesenchymal transition of prostate cancer cells via the Wnt/β-catenin pathway. 2020 Oct 1
44 33052244 Glycogen synthase kinase-3β: a promising candidate in the fight against fibrosis. 2020 2
45 33080467 The role of glycogen synthase kinase 3 beta in multiple sclerosis. 2020 Dec 1
46 33110983 Machine Learning for Discovery of GSK3β Inhibitors. 2020 Oct 20 2
47 33125126 Glycogen synthase kinase 3β in tumorigenesis and oncotherapy (Review). 2020 Dec 1
48 33343576 Inhibition of Glycogen Synthase Kinase 3β Increases the Proportion and Suppressive Function of CD19+CD24hiCD27+ Breg Cells. 2020 1
49 33362958 Dysregulated levels of glycogen synthase kinase-3β (GSK-3β) and miR-135 in peripheral blood samples of cases with nephrotic syndrome. 2020 1
50 29631413 Nanotized PPARα Overexpression Targeted to Hypertrophied Myocardium Improves Cardiac Function by Attenuating the p53-GSK3β-Mediated Mitochondrial Death Pathway. 2019 Feb 10 4