sirtinol

sirtuin 1 ; Mus musculus







46 Article(s)
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1 35396645 Both high glucose and phosphate overload promote senescence-associated calcification of vascular muscle cells. 2022 Apr 8 1
2 33361403 SIRT1 suppresses burn injury-induced inflammatory response through activating autophagy in RAW264.7 macrophages. 2021 Mar 2
3 33637069 Taohuajing reduces oxidative stress and inflammation in diabetic cardiomyopathy through the sirtuin 1/nucleotide-binding oligomerization domain-like receptor protein 3 pathway. 2021 Feb 26 2
4 34611179 The protective effect of the PDE-4 inhibitor rolipram on intracerebral haemorrhage is associated with the cAMP/AMPK/SIRT1 pathway. 2021 Oct 5 1
5 31105126 Estrogen-SIRT1 Axis Plays a Pivotal Role in Protecting Arteries Against Menopause-Induced Senescence and Atherosclerosis. 2020 Jan 1 2
6 31677062 Febuxostat, a novel inhibitor of xanthine oxidase, reduces ER stress through upregulation of SIRT1-AMPK-HO-1/thioredoxin expression. 2020 Mar 1
7 31877320 Role of AMPK/SIRT1-SIRT3 signaling pathway in affective disorders in unpredictable chronic mild stress mice. 2020 Mar 15 1
8 31900639 SIRT1 is required for the neuroprotection of resveratrol on retinal ganglion cells after retinal ischemia-reperfusion injury in mice. 2020 Feb 2
9 32145722 4-Hydroxybenzaldehyde Restricts the Intracellular Growth of Toxoplasma gondii by Inducing SIRT1-Mediated Autophagy in Macrophages. 2020 Feb 1
10 32289519 Sirtuin 1 deficiency decreases bone mass and increases bone marrow adiposity in a mouse model of chronic energy deficiency. 2020 Jul 1
11 30048156 Astaxanthin mitigates subarachnoid hemorrhage injury primarily by increasing sirtuin 1 and inhibiting the Toll-like receptor 4 signaling pathway. 2019 Jan 1
12 30614190 Sirt1-hypoxia-inducible factor-1α interaction is a key mediator of tubulointerstitial damage in the aged kidney. 2019 Apr 1
13 30739015 Deacetylation Inhibition Reverses PABPN1-Dependent Muscle Wasting. 2019 Feb 22 1
14 30771486 SIRT1 participates in the response to methylglyoxal-dependent glycative stress in mouse oocytes and ovary. 2019 Jun 1 1
15 30901738 The protective effect of oleanolic acid on NMDA-induced MLE-12 cells apoptosis and lung injury in mice by activating SIRT1 and reducing NF-κB acetylation. 2019 May 4
16 30910830 Crosstalk of PD-1 signaling with the SIRT1/FOXO-1 axis during the progression of visceral leishmaniasis. 2019 May 2 1
17 31340128 Effects of resveratrol postconditioning on cerebral ischemia in mice: role of the sirtuin-1 pathway. 2019 Nov 1
18 31481873 Hydrogen Sulfide Inhibits High Glucose-Induced Neuronal Senescence by Improving Autophagic Flux via Up-regulation of SIRT1. 2019 1
19 31497199 Inhibition of SIRT1 promotes taste bud stem cell survival and mitigates radiation-induced oral mucositis in mice. 2019 1
20 31677501 Ampelopsin attenuates carbon tetrachloride-induced mouse liver fibrosis and hepatic stellate cell activation associated with the SIRT1/TGF-β1/Smad3 and autophagy pathway. 2019 Dec 2
21 29312829 Formononetin inhibits lipopolysaccharide-induced release of high mobility group box 1 by upregulating SIRT1 in a PPARδ-dependent manner. 2018 1
22 29680657 Sirt1 S-nitrosylation induces acetylation of HMGB1 in LPS-activated RAW264.7 cells and endotoxemic mice. 2018 Jun 18 2
23 30355933 Resveratrol Activated Sonic Hedgehog Signaling to Enhance Viability of NIH3T3 Cells in Vitro via Regulation of Sirt1. 2018 1
24 26705390 BDNFVal66met polymorphism: a potential bridge between depression and thrombosis. 2017 May 7 1
25 28146117 Anti-Fibrotic Effect of Losartan, an Angiotensin II Receptor Blocker, Is Mediated through Inhibition of ER Stress via Up-Regulation of SIRT1, Followed by Induction of HO-1 and Thioredoxin. 2017 Jan 31 1
26 28213268 Fisetin inhibits IL-1β-induced inflammatory response in human osteoarthritis chondrocytes through activating SIRT1 and attenuates the progression of osteoarthritis in mice. 2017 Apr 2
27 28255111 [Sirtuin type 1 signaling pathway mediates the effect of diosgenin on chondrocyte metabolisms in osteoarthritis]. 2017 Feb 28 1
28 28526407 Sirtuin inhibition leads to autophagy and apoptosis in porcine preimplantation blastocysts. 2017 Jul 8 1
29 28966618 SIRT1/Adenosine Monophosphate-Activated Protein Kinase α Signaling Enhances Macrophage Polarization to an Anti-inflammatory Phenotype in Rheumatoid Arthritis. 2017 1
30 29090089 Sirtinol regulates the balance of Th17/Treg to prevent allograft rejection. 2017 2
31 26342525 Sirtuin 1 attenuates nasal polypogenesis by suppressing epithelial-to-mesenchymal transition. 2016 Jan 2
32 26795437 Fenofibrate increases cardiac autophagy via FGF21/SIRT1 and prevents fibrosis and inflammation in the hearts of Type 1 diabetic mice. 2016 Apr 1
33 27648127 Short-term starvation attenuates liver ischemia-reperfusion injury (IRI) by Sirt1-autophagy signaling in mice. 2016 1
34 27865166 Ethyl pyruvate inhibits the acetylation and release of HMGB1 via effects on SIRT1/STAT signaling in LPS-activated RAW264.7 cells and peritoneal macrophages. 2016 Dec 1
35 25930168 Pharmacologic investigations on the role of Sirt-1 in neuroprotective mechanism of postconditioning in mice. 2015 Jul 1
36 26170060 Suppression of RANKL-induced osteoclast differentiation by cilostazol via SIRT1-induced RANK inhibition. 2015 Oct 2
37 24466304 Sirtuin 1 (SIRT1) activation mediates sildenafil induced delayed cardioprotection against ischemia-reperfusion injury in mice. 2014 1
38 22085194 Neurons from senescence-accelerated SAMP8 mice are protected against frailty by the sirtuin 1 promoting agents melatonin and resveratrol. 2012 Apr 2
39 20978007 Sirt1 inhibition promotes in vivo arterial thrombosis and tissue factor expression in stimulated cells. 2011 Feb 1 1
40 21746786 SIRT-1 and vascular endothelial dysfunction with ageing in mice and humans. 2011 Sep 15 1
41 19995796 Inhibition of SIRT1 deacetylase suppresses estrogen receptor signaling. 2010 Mar 1
42 20493163 Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD. 2010 Aug 15 1
43 20610621 Resveratrol reverses endothelial nitric-oxide synthase uncoupling in apolipoprotein E knockout mice. 2010 Oct 1
44 20920189 Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression. 2010 Sep 28 1
45 21107122 Oral resveratrol reduces neuronal damage in a model of multiple sclerosis. 2010 Dec 1
46 19650880 Anti-aging properties of melatonin in an in vitro murine senescence model: involvement of the sirtuin 1 pathway. 2009 Oct 3