Triglycerides

nuclear receptor subfamily 1, group H, member 4 ; Mus musculus







40 Article(s)
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Pub. Year
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1 34778346 Dietary Phospholipids Prepared From Scallop Internal Organs Attenuate the Serum and Liver Cholesterol Contents by Enhancing the Expression of Cholesterol Hydroxylase in the Liver of Mice. 2021 2
2 34986301 The Effects of PPAR Agonists on Atherosclerosis and Nonalcoholic Fatty Liver Disease in ApoE-/-FXR-/- Mice. 2021 Dec 1
3 32003602 Bile acid treatment and FXR agonism lower postprandial lipemia in mice. 2020 Apr 1 2
4 32006644 Knockout of farnesoid X receptor aggravates process of diabetic cardiomyopathy. 2020 Mar 1
5 32062620 Taurine attenuates hepatic steatosis in a genetic model of fatty liver disease. 2020 1
6 32604760 Selenoneine Ameliorates Hepatocellular Injury and Hepatic Steatosis in a Mouse Model of NAFLD. 2020 Jun 26 1
7 29986186 Lipid reducing activity of novel cholic acid (CA) analogs: Design, synthesis and preliminary mechanism study. 2018 Oct 1
8 28378930 Hepatic FXR/SHP axis modulates systemic glucose and fatty acid homeostasis in aged mice. 2017 Aug 1
9 29142166 Fish oil feeding reverses hepatomegaly and disrupted hepatic function due to the lack of FXR signaling. 2017 1
10 29216638 MicroRNA-122 Inhibits Lipid Droplet Formation and Hepatic Triglyceride Accumulation via Yin Yang 1. 2017 1
11 25156247 Protective effects of farnesoid X receptor (FXR) on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signal. 2015 Apr 1
12 25425577 A dysregulated acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity. 2015 Jan 13 1
13 25500885 Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease. 2015 Jan 1
14 26909306 Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism. 2015 Dec 1
15 24038130 Hepatic carboxylesterase 1 is essential for both normal and farnesoid X receptor-controlled lipid homeostasis. 2014 May 3
16 24548803 FXR-dependent reduction of hepatic steatosis in a bile salt deficient mouse model. 2014 May 1
17 24747563 Bile acids override steatosis in farnesoid X receptor deficient mice in a model of non-alcoholic steatohepatitis. 2014 May 23 3
18 22197325 Impaired generation of 12-hydroxylated bile acids links hepatic insulin signaling with dyslipidemia. 2012 Jan 4 2
19 22540009 Farnesoid X receptor induces murine scavenger receptor Class B type I via intron binding. 2012 1
20 21862726 Farnesol, an isoprenoid, improves metabolic abnormalities in mice via both PPARα-dependent and -independent pathways. 2011 Nov 1
21 19998408 Bile salt sequestration induces hepatic de novo lipogenesis through farnesoid X receptor- and liver X receptor alpha-controlled metabolic pathways in mice. 2010 Mar 2
22 20431060 Farnesoid X receptor activation prevents the development of vascular calcification in ApoE-/- mice with chronic kidney disease. 2010 Jun 25 2
23 20631352 A role of the bile salt receptor FXR in atherosclerosis. 2010 Aug 1
24 20851881 The farnesoid X receptor regulates adipocyte differentiation and function by promoting peroxisome proliferator-activated receptor-gamma and interfering with the Wnt/beta-catenin pathways. 2010 Nov 19 1
25 18948497 Farnesoid X receptor deficiency induces nonalcoholic steatohepatitis in low-density lipoprotein receptor-knockout mice fed a high-fat diet. 2009 Jan 1
26 19028791 Antiatherosclerotic effect of farnesoid X receptor. 2009 Feb 1
27 19126757 Role of bile acids and bile acid receptors in metabolic regulation. 2009 Jan 5
28 19136377 A synthetic farnesoid X receptor (FXR) agonist promotes cholesterol lowering in models of dyslipidemia. 2009 Mar 2
29 19776172 The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria. 2009 Dec 1
30 18000141 Hypertriglyceridemia and hepatic steatosis in senescence-accelerated mouse associate to changes in lipid-related gene expression. 2007 Nov 1
31 16844773 Benefit of farnesoid X receptor inhibition in obstructive cholestasis. 2006 Jul 25 2
32 16936198 Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes. 2006 Sep 3
33 17110163 Effects of FXR in foam-cell formation and atherosclerosis development. 2006 Dec 3
34 15721319 Regulation of pyruvate dehydrogenase kinase expression by the farnesoid X receptor. 2005 Apr 1 1
35 14729567 Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR. 2004 Jan 15 3
36 15146238 Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c. 2004 May 1
37 12421815 The farnesoid X-receptor is an essential regulator of cholesterol homeostasis. 2003 Jan 24 1
38 12891557 Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression. 2003 Aug 2
39 11579204 Farnesoid X-activated receptor induces apolipoprotein C-II transcription: a molecular mechanism linking plasma triglyceride levels to bile acids. 2001 Oct 2
40 11030617 Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. 2000 Sep 15 2