CC-223

CREB regulated transcription coactivator 2 ; Mus musculus







5 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 31527867 A phase 2 study of an oral mTORC1/mTORC2 kinase inhibitor (CC-223) for non-pancreatic neuroendocrine tumors with or without carcinoid symptoms. 2019 1
2 29402408 CC-223 inhibits human head and neck squamous cell carcinoma cell growth. 2018 Feb 19 1
3 28334043 CC-223 blocks mTORC1/C2 activation and inhibits human hepatocellular carcinoma cells in vitro and in vivo. 2017 1
4 25855786 CC-223, a Potent and Selective Inhibitor of mTOR Kinase: In Vitro and In Vivo Characterization. 2015 Jun 1
5 26177599 A phase I dose-escalation study to assess safety, tolerability, pharmacokinetics, and preliminary efficacy of the dual mTORC1/mTORC2 kinase inhibitor CC-223 in patients with advanced solid tumors or multiple myeloma. 2015 Oct 1 2