Ethanol

mechanistic target of rapamycin kinase ; Homo sapiens







44 Article(s)
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1 33232716 Calcitriol alleviates ethanol-induced hepatotoxicity via AMPK/mTOR-mediated autophagy. 2021 Jan 15 1
2 33673489 Rapamycin Improves Recognition Memory and Normalizes Amino-Acids and Amines Levels in the Hippocampal Dentate Gyrus in Adult Rats Exposed to Ethanol during the Neonatal Period. 2021 Feb 27 1
3 33924998 Rapamycin Improves Spatial Learning Deficits, Vulnerability to Alcohol Addiction and Altered Expression of the GluN2B Subunit of the NMDA Receptor in Adult Rats Exposed to Ethanol during the Neonatal Period. 2021 Apr 28 2
4 31955628 Caffeine Potentiates Ethanol-Induced Neurotoxicity Through mTOR/p70S6K/4E-BP1 Inhibition in SH-SY5Y Cells. 2020 Mar/Apr 4
5 32411003 Ethanol Extract of Brucea javanica Seed Inhibit Triple-Negative Breast Cancer by Restraining Autophagy via PI3K/Akt/mTOR Pathway. 2020 1
6 32428938 Artemisiae Iwayomogii Herba Inhibits Growth, Motility, and the PI3K/AKT/mTOR Signaling Pathway in Hepatocellular Carcinoma Cells. 2020 Jul 1
7 32721464 MicroRNA-708 prevents ethanol-induced hepatic lipid accumulation and inflammatory reaction via direct targeting ZEB1. 2020 Oct 1 2
8 33199776 A meta-analysis of the effect of binge drinking on the oral microbiome and its relation to Alzheimer's disease. 2020 Nov 16 1
9 30529756 Minocycline attenuates ethanol-induced cell death and microglial activation in the developing spinal cord. 2019 Sep 2
10 30553838 Augmenter of Liver Regeneration Protects against Ethanol-Induced Acute Liver Injury by Promoting Autophagy. 2019 Mar 1
11 31586901 Betaine alleviates alcohol-induced osteonecrosis of the femoral head via mTOR signaling pathway regulation. 2019 Dec 3
12 31637215 mTOR/HDAC1 Crosstalk Mediated Suppression of ADH1A and ALDH2 Links Alcohol Metabolism to Hepatocellular Carcinoma Onset and Progression in silico. 2019 1
13 28466267 17β-Estradiol via SIRT1/Acetyl-p53/NF-kB Signaling Pathway Rescued Postnatal Rat Brain Against Acute Ethanol Intoxication. 2018 Apr 2
14 29251317 Ethanol extract of Patrinia scabiosaefolia induces the death of human renal cell carcinoma 786-O cells via SIRT-1 and mTOR signaling-mediated metabolic disruptions. 2018 Feb 1
15 29368944 A specific amino acid formula prevents alcoholic liver disease in rodents. 2018 May 1 1
16 29457836 DEP domain-containing mTOR-interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute-on-chronic liver injury in alcoholic liver disease. 2018 Aug 1
17 29807029 Involvement of mTOR, JNK and PI3K in the negative effect of ethanol and metformin on the human first-trimester extravillous trophoblast HTR-8/SVneo cell line. 2018 Aug 15 3
18 29895782 Effects of Melatonin and Its Underlying Mechanism on Ethanol-Stimulated Senescence and Osteoclastic Differentiation in Human Periodontal Ligament Cells and Cementoblasts. 2018 Jun 12 2
19 30607146 Chemopreventive and biological activities of Helicteres isora L. fruit extracts. 2018 Dec 2
20 28539965 Chemicals Compositions, Antioxidant and Anti-Inflammatory Activity of Cynara scolymus Leaves Extracts, and Analysis of Major Bioactive Polyphenols by HPLC. 2017 1
21 29062364 Alcohol Inhibits Odontogenic Differentiation of Human Dental Pulp Cells by Activating mTOR Signaling. 2017 6
22 26775950 Phenolic compounds of Brazilian beers from different types and styles and application of chemometrics for modeling antioxidant capacity. 2016 May 15 1
23 27618151 Sporoderm-Broken Spores of Ganoderma lucidum Inhibit the Growth of Lung Cancer: Involvement of the Akt/mTOR Signaling Pathway. 2016 Oct 1
24 25623400 Alcohol intoxication following muscle contraction in mice decreases muscle protein synthesis but not mTOR signal transduction. 2015 Jan 4
25 25670261 Ethanol extract of Remotiflori radix induces endoplasmic reticulum stress-mediated cell death through AMPK/mTOR signaling in human prostate cancer cells. 2015 Feb 11 1
26 25849580 Distinct inhibitory effects on mTOR signaling by ethanol and INK128 in diffuse large B-cell lymphoma. 2015 Mar 1 10
27 24680568 Alcohol consumption mitigates apoptosis and mammalian target of rapamycin signaling in myocardium. 2014 Jun 1
28 25257868 Alcohol impairs skeletal muscle protein synthesis and mTOR signaling in a time-dependent manner following electrically stimulated muscle contraction. 2014 Nov 15 2
29 25484085 Autophagy and ethanol neurotoxicity. 2014 1
30 23412940 Upregulation of HO-1 is accompanied by activation of p38MAPK and mTOR in human oesophageal squamous carcinoma cells. 2013 Jun 1
31 23895284 Activation of AMPK/TSC2/PLD by alcohol regulates mTORC1 and mTORC2 assembly in C2C12 myocytes. 2013 Nov 1
32 22442136 Rag GTPases and AMPK/TSC2/Rheb mediate the differential regulation of mTORC1 signaling in response to alcohol and leucine. 2012 May 15 3
33 22451512 Deficiency in AMPK attenuates ethanol-induced cardiac contractile dysfunction through inhibition of autophagosome formation. 2012 Jun 1 1
34 22874567 Autophagy is a protective response to ethanol neurotoxicity. 2012 Nov 3
35 21150309 Selective taste of ethanol-induced autophagy for mitochondria and lipid droplets. 2011 Feb 1
36 21438886 Alcohol-induced modulation of rictor and mTORC2 activity in C2C12 myoblasts. 2011 Aug 2
37 21964292 Restoration of autophagy by puerarin in ethanol-treated hepatocytes via the activation of AMP-activated protein kinase. 2011 Oct 22 2
38 20127721 Alcohol and PRAS40 knockdown decrease mTOR activity and protein synthesis via AMPK signaling and changes in mTORC1 interaction. 2010 Apr 15 4
39 20372065 Reduced mortality and moderate alcohol consumption: the phospholipase D-mTOR connection. 2010 Apr 1 1
40 20659474 Autophagy reduces acute ethanol-induced hepatotoxicity and steatosis in mice. 2010 Nov 1
41 19293424 Alcohol consumption and decreased risk of non-Hodgkin lymphoma: role of mTOR dysfunction. 2009 May 28 6
42 18336631 Acute alcohol intoxication increases REDD1 in skeletal muscle. 2008 May 2
43 17164244 Alcohol regulates eukaryotic elongation factor 2 phosphorylation via an AMP-activated protein kinase-dependent mechanism in C2C12 skeletal myocytes. 2007 Feb 9 1
44 12944322 Alcohol impairs leucine-mediated phosphorylation of 4E-BP1, S6K1, eIF4G, and mTOR in skeletal muscle. 2003 Dec 2