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34983907 | Mammalian Target of Rapamycin as the Therapeutic Target of Vascular Proliferative Diseases: Past, Present, and Future. | 2022 Apr 1 |
2 |
| 2 |
34996736 | Disentangling the signaling pathways of mTOR complexes, mTORC1 and mTORC2, as a therapeutic target in glioblastoma. | 2022 Jan |
1 |
| 3 |
35001007 | Reconstruction and Exploratory Analysis of mTORC1 Signaling Pathway and Its Applications to Various Diseases Using Network-Based Approach. | 2022 Mar 28 |
2 |
| 4 |
35018844 | Biomarkers of everolimus efficacy in breast cancer therapy. | 2022 Jun |
1 |
| 5 |
35125881 | An Analysis of the Pathogenic Genes and Mutation Sites of Macrodactyly. | 2022 |
1 |
| 6 |
35163615 | Predominant Role of mTOR Signaling in Skin Diseases with Therapeutic Potential. | 2022 Feb 1 |
2 |
| 7 |
35176419 | p70 S6 kinase as a therapeutic target in cancers: More than just an mTOR effector. | 2022 Jun 1 |
1 |
| 8 |
35226587 | ULK3-dependent activation of GLI1 promotes DNMT3A expression upon autophagy induction. | 2022 Feb 28 |
1 |
| 9 |
35547877 | Vitamin D Reverts the Exosome-Mediated Transfer of Cancer Resistance to the mTOR Inhibitor Everolimus in Hepatocellular Carcinoma. | 2022 |
1 |
| 10 |
35633587 | Neuroprotection of everolimus against focal cerebral ischemia-reperfusion injury in rats. | 2022 May 25 |
2 |
| 11 |
33411714 | Extracellular vesicles released from the filarial parasite Brugia malayi downregulate the host mTOR pathway. | 2021 Jan |
3 |
| 12 |
33411856 | TRK-Fused Gene (TFG), a protein involved in protein secretion pathways, is an essential component of the antiviral innate immune response. | 2021 Jan |
2 |
| 13 |
33504218 | Targeting PRAS40: a novel therapeutic strategy for human diseases. | 2021 Aug |
1 |
| 14 |
33594306 | Formononetin ameliorates the drug resistance of Taxol resistant triple negative breast cancer by inhibiting autophagy. | 2021 |
2 |
| 15 |
33643212 | The Putative Role of mTOR Inhibitors in Non-tuberous Sclerosis Complex-Related Epilepsy. | 2021 |
1 |
| 16 |
33673489 | Rapamycin Improves Recognition Memory and Normalizes Amino-Acids and Amines Levels in the Hippocampal Dentate Gyrus in Adult Rats Exposed to Ethanol during the Neonatal Period. | 2021 Feb 27 |
2 |
| 17 |
33774181 | Properties of FDA-approved small molecule phosphatidylinositol 3-kinase inhibitors prescribed for the treatment of malignancies. | 2021 Jun |
1 |
| 18 |
33801030 | Marine-Derived Natural Products as ATP-Competitive mTOR Kinase Inhibitors for Cancer Therapeutics. | 2021 Mar 21 |
2 |
| 19 |
33802884 | Theasaponin E1 Inhibits Platinum-Resistant Ovarian Cancer Cells through Activating Apoptosis and Suppressing Angiogenesis. | 2021 Mar 17 |
2 |
| 20 |
33835469 | Cytonuclear Estrogen Receptor Alpha Regulates Proliferation and Migration of Endometrial Carcinoma Cells. | 2021 Apr 20 |
1 |
| 21 |
33923895 | Assessment and Imaging of Intracellular Magnesium in SaOS-2 Osteosarcoma Cells and Its Role in Proliferation. | 2021 Apr 20 |
1 |
| 22 |
33933601 | mTOR in Alzheimer disease and its earlier stages: Links to oxidative damage in the progression of this dementing disorder. | 2021 Jun |
2 |
| 23 |
33952452 | Combined Targeting of AKT and mTOR Synergistically Inhibits Formation of Primary Colorectal Carcinoma Tumouroids In Vitro: A 3D Tumour Model for Pre-therapeutic Drug Screening. | 2021 May |
1 |
| 24 |
33995085 | AKT Inhibitors: New Weapons in the Fight Against Breast Cancer? | 2021 |
1 |
| 25 |
33998365 | Everolimus attenuates glutamate-induced PC12 cells death. | 2021 May 17 |
2 |
| 26 |
34102579 | mTOR pathway and DNA damage response: A therapeutic strategy in cancer therapy. | 2021 Aug |
2 |
| 27 |
34130564 | Cancer cells dysregulate PI3K/AKT/mTOR pathway activation to ensure their survival and proliferation: mimicking them is a smart strategy of gammaherpesviruses. | 2021 Oct |
2 |
| 28 |
34132942 | mTOR-Rictor-EGFR axis in oncogenesis and diagnosis of glioblastoma multiforme. | 2021 May |
2 |
| 29 |
34183390 | Cisplatin and Pemetrexed Have Distinctive Growth-inhibitory Effects in Monotherapy and Combination Therapy on KRAS-dependent A549 Lung Cancer Cells. | 2021 Jul-Aug |
1 |
| 30 |
34194551 | miR-320a in serum exosomes promotes myocardial fibroblast proliferation via regulating the PIK3CA/Akt/mTOR signaling pathway in HEH2 cells. | 2021 Aug |
1 |
| 31 |
34215308 | Mammalian/mechanistic target of rapamycin (mTOR) complexes in neurodegeneration. | 2021 Jul 2 |
1 |
| 32 |
34452154 | Inhibitors of the PI3K/Akt/mTOR Pathway in Prostate Cancer Chemoprevention and Intervention. | 2021 Aug 3 |
1 |
| 33 |
34458019 | Prognostic significance and tumor-immune infiltration of mTOR in clear cell renal cell carcinoma. | 2021 |
2 |
| 34 |
34464661 | The Akt-mTOR network at the interface of hematopoietic stem cell homeostasis. | 2021 Nov |
2 |
| 35 |
34515612 | miR-337-5p promotes the development of cardiac hypertrophy by targeting Ubiquilin-1 (UBQLN1). | 2021 Dec |
1 |
| 36 |
34600886 | The deubiquitinase USP11 is a versatile and conserved regulator of autophagy. | 2021 Nov |
1 |
| 37 |
34634301 | Tyrosine phosphorylation of DEPTOR functions as a molecular switch to activate mTOR signaling. | 2021 Nov |
1 |
| 38 |
34712915 | Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity. | 2021 Nov 19 |
2 |
| 39 |
34716294 | BET protein inhibition evidently enhances sensitivity to PI3K/mTOR dual inhibition in intrahepatic cholangiocarcinoma. | 2021 Oct 29 |
2 |
| 40 |
34855399 | Design, Synthesis, and Evaluation of Potent, Selective, and Bioavailable AKT Kinase Degraders. | 2021 Dec 23 |
1 |
| 41 |
34869377 | The Cross Talk Between p53 and mTOR Pathways in Response to Physiological and Genotoxic Stresses. | 2021 |
2 |
| 42 |
35178356 | Role of mTOR Complex 1 Signaling Pathway in the Pathogenesis of Diabetes Complications; A Mini Review. | 2021 Summer |
2 |
| 43 |
30270668 | Regulation of insulin resistance and glucose metabolism by interaction of PIM kinases and insulin receptor substrates. | 2020 May |
1 |
| 44 |
31902918 | Metformin Suppresses LPS-Induced Inflammatory Responses in Macrophage and Ameliorates Allergic Contact Dermatitis in Mice via Autophagy. | 2020 |
1 |
| 45 |
32058690 | Molecular Networking and Whole-Genome Analysis Aid Discovery of an Angucycline That Inactivates mTORC1/C2 and Induces Programmed Cell Death. | 2020 Mar 20 |
2 |
| 46 |
32317083 | Serine 389 phosphorylation of 3-phosphoinositide-dependent kinase 1 by UNC-51-like kinase 1 affects its ability to regulate Akt and p70 S6kinase. | 2020 Jul |
2 |
| 47 |
32323755 | AMPK activation protects astrocytes from hypoxia‑induced cell death. | 2020 May |
2 |
| 48 |
32377533 | The Regulatory Effects of mTOR Complexes in the Differentiation and Function of CD4+ T Cell Subsets. | 2020 |
2 |
| 49 |
32416459 | Targeting mTOR for fighting diseases: A revisited review of mTOR inhibitors. | 2020 Aug 1 |
2 |
| 50 |
32486385 | A Phase 1 Study of mTORC1/2 Inhibitor BI 860585 as a Single Agent or with Exemestane or Paclitaxel in Patients with Advanced Solid Tumors. | 2020 May 31 |
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