pevonedistat

mechanistic target of rapamycin kinase ; Homo sapiens







5 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 32983997 Targeting Cullin-RING E3 Ligases for Radiosensitization: From NEDDylation Inhibition to PROTACs. 2020 1
2 30699367 Effects of Neddylation and mTOR Inhibition in Acute Myelogenous Leukemia. 2019 Apr 1
3 27626202 The NEDD8-activating enzyme inhibitor pevonedistat activates the eIF2α and mTOR pathways inducing UPR-mediated cell death in acute lymphoblastic leukemia. 2016 Nov 2
4 24430184 Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis. 2014 Feb 1
5 24713927 MLN4924, an NAE inhibitor, suppresses AKT and mTOR signaling via upregulation of REDD1 in human myeloma cells. 2014 May 22 1