Quercetin

mechanistic target of rapamycin kinase ; Homo sapiens







37 Article(s)
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1 35412948 Quercetin inhibits fibroblasts proliferation and reduces surgery-induced epidural fibrosis via the autophagy-mediated PI3K/Akt/mTOR pathway. 2022 Apr 1
2 32900356 Quercetin Inhibits AQP1 Translocation in High-Glucose-Cultured SRA01/04 Cells Through PI3K/Akt/mTOR Pathway. 2021 Oct 25 4
3 33141412 Ameliorative Effects of Quercetin and Metformin and Their Combination Against Experimental Endometriosis in Rats. 2021 Mar 1
4 34159683 Quercetin as a protective agent for liver diseases: A comprehensive descriptive review of the molecular mechanism. 2021 Sep 2
5 34308732 Quercetin protects oral mucosal keratinocytes against lipopolysaccharide-induced inflammatory toxicity by suppressing the AKT/AMPK/mTOR pathway. 2021 Oct 4
6 32179074 Anti-fibrosis activity of quercetin attenuates rabbit tracheal stenosis via the TGF-β/AKT/mTOR signaling pathway. 2020 Jun 1 1
7 32553736 Quercetin attenuates diabetic neuropathic pain by inhibiting mTOR/p70S6K pathway-mediated changes of synaptic morphology and synaptic protein levels in spinal dorsal horn of db/db mice. 2020 Sep 5 2
8 30596535 Quercetin, a Plant Polyphenol, Has Potential for the Prevention of Bone Destruction in Rheumatoid Arthritis. 2019 Feb 1
9 31137633 Quercetin Inhibits the Proliferation of Glycolysis-Addicted HCC Cells by Reducing Hexokinase 2 and Akt-mTOR Pathway. 2019 May 24 1
10 31261749 The Anti-Cancer Effect of Quercetin: Molecular Implications in Cancer Metabolism. 2019 Jun 28 1
11 31590760 Quercetin facilitates cell death and chemosensitivity through RAGE/PI3K/AKT/mTOR axis in human pancreatic cancer cells. 2019 Oct 1
12 29355544 Quercetin suppresses breast cancer stem cells (CD44+/CD24-) by inhibiting the PI3K/Akt/mTOR-signaling pathway. 2018 Mar 1 2
13 29438776 Quercetin ameliorates HFD-induced NAFLD by promoting hepatic VLDL assembly and lipophagy via the IRE1a/XBP1s pathway. 2018 Apr 1
14 29537893 Inhibition of mTOR/S6K1/4E-BP1 Signaling by Nutraceutical SIRT1 Modulators. 2018 Apr 1
15 29781726 In-Vitro Analysis of Glucose and Quercetin Effects on m-TOR and Nrf-2 Expression in HepG2 Cell Line (Diabetes and Cancer Connection). 2018 Jul 1
16 29976410 Flavonoids Luteolin and Quercetin Inhibit RPS19 and contributes to metastasis of cancer cells through c-Myc reduction. 2018 Jul 2
17 30025823 Quercetin suppresses the mobility of breast cancer by suppressing glycolysis through Akt-mTOR pathway mediated autophagy induction. 2018 Sep 1 5
18 30510622 Enhancing TFEB-Mediated Cellular Degradation Pathways by the mTORC1 Inhibitor Quercetin. 2018 1
19 27979659 Quercetin induces autophagy via FOXO1-dependent pathways and autophagy suppression enhances quercetin-induced apoptosis in PASMCs in hypoxia. 2017 Feb 2
20 28063518 Role of nutraceutical SIRT1 modulators in AMPK and mTOR pathway: Evidence of a synergistic effect. 2017 Feb 1
21 28092744 Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways. 2017 Mar 2
22 29069736 A novel synthetic derivative of quercetin, 8-trifluoromethyl-3,5,7,3',4'-O-pentamethyl-quercetin, inhibits bladder cancer growth by targeting the AMPK/mTOR signaling pathway. 2017 Sep 22 2
23 26648539 Suppression of HSP27 increases the anti‑tumor effects of quercetin in human leukemia U937 cells. 2016 Jan 2
24 27052477 Quercetin Inhibits Fibroblast Activation and Kidney Fibrosis Involving the Suppression of Mammalian Target of Rapamycin and β-catenin Signaling. 2016 Apr 7 2
25 27285995 Anti-Breast Cancer Potential of Quercetin via the Akt/AMPK/Mammalian Target of Rapamycin (mTOR) Signaling Cascade. 2016 3
26 27620077 Concomitant reduction of c-Myc expression and PI3K/AKT/mTOR signaling by quercetin induces a strong cytotoxic effect against Burkitt's lymphoma. 2016 Oct 3
27 27621033 Quercetin nanoparticles induced autophagy and apoptosis through AKT/ERK/Caspase-3 signaling pathway in human neuroglioma cells: In vitro and in vivo. 2016 Dec 2
28 30549596 Evaluation of Antioxidant Interactions of Combined Model Systems of Phenolics in the Presence of Sugars. 2016 Oct 1
29 26261493 Synergistic effects of snail and quercetin on renal cell carcinoma Caki-2 by altering AKT/mTOR/ERK1/2 signaling pathways. 2015 1
30 26560479 The antiradical activity of some selected flavones and flavonols. Experimental and quantum mechanical study. 2015 Dec 1
31 25087994 Quercetin attenuates renal ischemia/reperfusion injury via an activation of AMP-activated protein kinase-regulated autophagy pathway. 2014 Nov 2
32 23272907 Inhibition of mTOR signaling by quercetin in cancer treatment and prevention. 2013 Sep 8
33 25337554 Quercetin Regulates Sestrin 2-AMPK-mTOR Signaling Pathway and Induces Apoptosis via Increased Intracellular ROS in HCT116 Colon Cancer Cells. 2013 Sep 3
34 21993664 Proteasome inhibition by quercetin triggers macroautophagy and blocks mTOR activity. 2012 Jan 4
35 22765290 Plant natural compounds: targeting pathways of autophagy as anti-cancer therapeutic agents. 2012 Oct 1
36 23094058 Quercetin inhibits angiogenesis mediated human prostate tumor growth by targeting VEGFR- 2 regulated AKT/mTOR/P70S6K signaling pathways. 2012 4
37 19548565 [Research on the evaluation methods for antioxidant capacity of several bioactive substances in vitro]. 2009 May 2