Curcumin

mechanistic target of rapamycin kinase ; Homo sapiens







116 Article(s)
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1 34634291 Curcumin induces autophagic cell death in human thyroid cancer cells. 2022 Feb 1
2 35319355 Curcumin nanofibers: A novel approach to enhance the anticancer potential and bioavailability of curcuminoids. 2022 Mar 22 1
3 35399832 Curcumin Inhibits the Proliferation of Renal Cancer 786-O Cells through MTOR Signaling Pathway and Its Mechanism. 2022 5
4 35409397 Metabolic Reconfiguration Activates Stemness and Immunomodulation of PDLSCs. 2022 Apr 6 1
5 35454103 Curcumin and Ethanol Effects in Trembler-J Schwann Cell Culture. 2022 Mar 29 1
6 33527008 Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma. 2021 1
7 34051214 Curcumin increases heat shock protein 70 expression via different signaling pathways in intestinal epithelial cells. 2021 Aug 15 1
8 34109436 Curcumin induces apoptosis by inhibiting BCAT1 expression and mTOR signaling in cytarabine‑resistant myeloid leukemia cells. 2021 Aug 3
9 34257809 The Combination Treatment of Curcumin and Probucol Protects Chondrocytes from TNF-α Induced Inflammation by Enhancing Autophagy and Reducing Apoptosis via the PI3K-Akt-mTOR Pathway. 2021 3
10 34298639 Curcumin: Modulator of Key Molecular Signaling Pathways in Hormone-Independent Breast Cancer. 2021 Jul 8 1
11 34323067 Regulation on Citrate Influx and Metabolism through Inhibiting SLC13A5 and ACLY: A Novel Mechanism Mediating the Therapeutic Effects of Curcumin on NAFLD. 2021 Aug 11 1
12 34323243 Curcumin enhances the membrane trafficking of the sodium iodide symporter and augments radioiodine uptake in dedifferentiated thyroid cancer cells via suppression of the PI3K-AKT signaling pathway. 2021 Sep 20 1
13 34402718 Curcumin induces apoptosis and autophagy inhuman renal cell carcinoma cells via Akt/mTOR suppression. 2021 Dec 4
14 34408780 Curcumin Inhibits HGF-Induced EMT by Regulating c-MET-Dependent PI3K/Akt/mTOR Signaling Pathways in Meningioma. 2021 3
15 34791915 Curcumin and resveratrol inhibit chemoresistance in cisplatin-resistant epithelial ovarian cancer cells via targeting P13K pathway. 2021 Dec 1
16 34832850 New Insights into Curcumin- and Resveratrol-Mediated Anti-Cancer Effects. 2021 Oct 22 1
17 34981469 Evaluation of the Effects of Nanomicellar Curcumin, Berberine, and Their Combination with 5-Fluorouracil on Breast Cancer Cells. 2021 1
18 31843707 Curcumin attenuates cognitive impairment by enhancing autophagy in chemotherapy. 2020 Mar 1
19 31863822 Curcumin analog, WZ37, promotes G2/M arrest and apoptosis of HNSCC cells through Akt/mTOR inhibition. 2020 Jun 1
20 31980182 Curcumin exerts anti-tumor effects on diffuse large B cell lymphoma via regulating PPARγ expression. 2020 Mar 26 1
21 32067269 Curcumin inhibits cell viability, migration, and invasion of thymic carcinoma cells via downregulation of microRNA-27a. 2020 Jul 2
22 32074070 Curcumin inhibits migration and invasion of non-small cell lung cancer cells through up-regulation of miR-206 and suppression of PI3K/AKT/mTOR signaling pathway. 2020 Sep 1 3
23 32278045 The anticancer effects of curcumin via targeting the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway. 2020 Jun 1
24 32445778 Curcumin suppresses glioblastoma cell proliferation by p-AKT/mTOR pathway and increases the PTEN expression. 2020 Aug 15 2
25 32519340 Versatile role of curcumin and its derivatives in lung cancer therapy. 2020 Dec 1
26 32526690 Curcumin blunts epithelial-mesenchymal transition of hepatocytes to alleviate hepatic fibrosis through regulating oxidative stress and autophagy. 2020 Sep 1
27 32628350 Curcumin downregulates the PI3K-AKT-mTOR pathway and inhibits growth and progression in head and neck cancer cells. 2020 Dec 4
28 32968631 Curcumin suppresses doxorubicin-induced cardiomyocyte pyroptosis via a PI3K/Akt/mTOR-dependent manner. 2020 Aug 1
29 33171062 Identification of curcumin as a novel natural inhibitor of rDNA transcription. 2020 Dec 1
30 33292283 Resveratrol, curcumin, paclitaxel and miRNAs mediated regulation of PI3K/Akt/mTOR pathway: go four better to treat bladder cancer. 2020 Nov 23 1
31 30392062 Curcumin ameliorates PRMT5-MEP50 arginine methyltransferase expression by decreasing the Sp1 and NF-YA transcription factors in the A549 and MCF-7 cells. 2019 May 1
32 30483727 Molecular targets of curcumin in breast cancer (Review). 2019 Jan 1
33 30569107 Curcumin inhibits high glucose‑induced inflammatory injury in human retinal pigment epithelial cells through the ROS‑PI3K/AKT/mTOR signaling pathway. 2019 Feb 1
34 30655872 Curcumin-induced promoter hypermethylation of the mammalian target of rapamycin gene in multiple myeloma cells. 2019 Jan 5
35 30747999 Curcumin reduces development of seizurelike events in the hippocampal-entorhinal cortex slice culture model for epileptogenesis. 2019 Apr 1
36 30918132 Curcumin Ameliorates Chronic Renal Failure in 5/6 Nephrectomized Rats by Regulation of the mTOR/HIF-1α/VEGF Signaling Pathway. 2019 Jun 1 2
37 31006841 Curcumin induces apoptotic cell death and protective autophagy by inhibiting AKT/mTOR/p70S6K pathway in human ovarian cancer cells. 2019 Jun 2
38 31091659 Curcumin Treatment in Combination with Glucose Restriction Inhibits Intracellular Alkalinization and Tumor Growth in Hepatoma Cells. 2019 May 14 1
39 31092832 Possible activation of NRF2 by Vitamin E/Curcumin against altered thyroid hormone induced oxidative stress via NFĸB/AKT/mTOR/KEAP1 signalling in rat heart. 2019 May 15 2
40 31295875 Role of Autophagy on Heavy Metal-Induced Renal Damage and the Protective Effects of Curcumin in Autophagy and Kidney Preservation. 2019 Jul 10 2
41 31316146 Chemopreventive Effect of Phytosomal Curcumin on Hepatitis B Virus-Related Hepatocellular Carcinoma in A Transgenic Mouse Model. 2019 Jul 17 1
42 31316605 Curcumin suppresses intestinal microvascular endothelial cells invasion and angiogenesis induced by activated platelets. 2019 Aug 1
43 31332165 Homocysteine enhances neural stem cell autophagy in in vivo and in vitro model of ischemic stroke. 2019 Jul 22 1
44 31511778 Curcumin Inhibits Joint Contracture through PTEN Demethylation and Targeting PI3K/Akt/mTOR Pathway in Myofibroblasts from Human Joint Capsule. 2019 1
45 31841506 Combination treatment of berberine and solid lipid curcumin particles increased cell death and inhibited PI3K/Akt/mTOR pathway of human cultured glioblastoma cells more effectively than did individual treatments. 2019 1
46 31976028 Restoration of Autophagic Flux Rescues Oxidative Damage and Mitochondrial Dysfunction to Protect against Intervertebral Disc Degeneration. 2019 1
47 28926094 Curcumin regulates proliferation, autophagy, and apoptosis in gastric cancer cells by affecting PI3K and P53 signaling. 2018 Jun 1
48 29322144 Structure, gelation, and antioxidant properties of curcumin-doped casein micelle powder produced by spray-drying. 2018 Feb 21 1
49 29328421 Antitumor activity of curcumin by modulation of apoptosis and autophagy in human lung cancer A549 cells through inhibiting PI3K/Akt/mTOR pathway. 2018 Mar 11
50 29533214 Curcumin analogue 1,5-bis(4-hydroxy-3-((4-methylpiperazin-1-yl)methyl)phenyl)penta-1,4-dien-3-one mediates growth arrest and apoptosis by targeting the PI3K/AKT/mTOR and PKC-theta signaling pathways in human breast carcinoma cells. 2018 Aug 1