Glucose

mechanistic target of rapamycin kinase ; Homo sapiens







306 Article(s)
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1 33933315 Epigenetic changes related to glucose metabolism in type 1 diabetes after BCG vaccinations: A vital role for KDM2B. 2022 Mar 8 2
2 34036900 Autophagy in metabolism and quality control: opposing, complementary or interlinked functions? 2022 Feb 1
3 34376311 A targeted approach to phosphoinositide-3-kinase/Akt/mammalian target of rapamycin-induced hyperglycemia. 2022 Feb 1
4 34636125 Procyanidin protects human retinal pigment epithelial cells from high glucose by inhibiting autophagy. 2022 Feb 1
5 35014047 The pro-proliferative effect of insulin in human breast epithelial DMBA-transformed and non-transformed cell lines is PI3K-, mTOR- and GLUT1-dependent. 2022 Mar 1
6 35043378 Bupivacaine Induces ROS-Dependent Autophagic Damage in DRG Neurons via TUG1/mTOR in a High-Glucose Environment. 2022 Feb 2
7 35069879 CRNDE silencing promotes apoptosis and enhances cisplatin sensitivity of colorectal carcinoma cells by inhibiting the Akt/mTORC1-mediated Warburg effect. 2022 Feb 1
8 35165542 Unraveling the Role of STK11/LKB1 in Non-small Cell Lung Cancer. 2022 Jan 1
9 35192961 Comorbidity of osteoporosis and Alzheimer's disease: Is `AKT `-ing on cellular glucose uptake the missing link? 2022 Apr 1
10 35412588 Interferon-a potentiates anti-PD-1 efficacy by remodeling glucose metabolism in the hepatocellular carcinoma microenvironment. 2022 Apr 12 1
11 35415942 Effect of Glut-1 and HIF-1α double knockout by CRISPR/CAS9 on radiosensitivity in laryngeal carcinoma via the PI3K/Akt/mTOR pathway. 2022 May 1
12 35524821 Canonical insulin signaling is not significantly impaired in early stages of depression. 2022 May 7 2
13 35576438 Telaglenastat Plus Everolimus in Advanced Renal Cell Carcinoma: A Randomized, Double-Blinded, Placebo-Controlled, Phase 2 ENTRATA Trial. 2022 May 16 1
14 32627660 Regulation and repurposing of nutrient sensing and autophagy in innate immunity. 2021 Jul 2
15 32755490 Does high dietary protein intake contribute to the increased risk of developing prediabetes and type 2 diabetes? 2021 Jan 1
16 32900356 Quercetin Inhibits AQP1 Translocation in High-Glucose-Cultured SRA01/04 Cells Through PI3K/Akt/mTOR Pathway. 2021 Oct 25 2
17 33367927 Critical role of mTOR in regulating aerobic glycolysis in carcinogenesis (Review). 2021 Jan 1
18 33441223 [Down-regulation of PHLPP1 expression ameliorates high glucose-induced autophagy inhibition and apoptosis promotion of podocytes by activating PI3K/AKT/mTOR pathway]. 2021 Jan 1
19 33523960 Adiponectin receptor 1 variants contribute to hypertrophic cardiomyopathy that can be reversed by rapamycin. 2021 Jan 1
20 33716662 Integration of Nutrient Sensing in Fish Hypothalamus. 2021 2
21 33764985 Elevated glucose represses lysosomal and mTOR-related genes in renal epithelial cells composed of progenitor CD133+ cells. 2021 7
22 33815116 Vildagliptin Attenuates Myocardial Dysfunction and Restores Autophagy via miR-21/SPRY1/ERK in Diabetic Mice Heart. 2021 1
23 33857309 SGLT2 Inhibitors as Calorie Restriction Mimetics: Insights on Longevity Pathways and Age-Related Diseases. 2021 Aug 1 1
24 33872751 Glucose starvation greatly enhances antiproliferative and antiestrogenic potency of oligomycin A in MCF-7 breast cancer cells. 2021 Jul 1
25 34051232 Glucose treatment of human pancreatic β-cells enhances translation of mRNAs involved in energetics and insulin secretion. 2021 Jul 1
26 34119651 Review: Schistosoma mansoni phosphatidylinositol 3 kinase (PI3K)/Akt/mechanistic target of rapamycin (mTOR) signaling pathway. 2021 Oct-Dec 1
27 34140929 O-GlcNAcylation in Hyperglycemic Pregnancies: Impact on Placental Function. 2021 1
28 34150534 Autophagy dysregulation mediates the damage of high glucose to retinal pigment epithelium cells. 2021 1
29 34281282 Low-Dose Acrolein, an Endogenous and Exogenous Toxic Molecule, Inhibits Glucose Transport via an Inhibition of Akt-Regulated GLUT4 Signaling in Skeletal Muscle Cells. 2021 Jul 5 1
30 34309456 The role of mTOR in age-related diseases. 2021 Dec 1
31 34326951 Current cancer therapies and their influence on glucose control. 2021 Jul 15 1
32 34399087 Dexamethasone may inhibit placental growth by blocking glucocorticoid receptors via phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin and reactive oxygen species/AMP-activated protein kinase signalling pathways in human placental JEG-3 cells. 2021 Oct 1
33 34486387 Metformin Rescues the Impaired Osteogenesis Differentiation Ability of Rat Adipose-Derived Stem Cells in High Glucose by Activating Autophagy. 2021 Oct 15 1
34 34590575 [Research progress on the roles and mechanisms underlying metabolic molecules involved in nutrition therapy and immune regulation in sepsis]. 2021 Aug 1
35 34619345 Dihydroartemisinin ameliorates retinal vascular dysfunction in diabetes mellitus via the FASN/Kmal-mTOR/SREBP1 feedback loop. 2021 Dec 1
36 34630911 Culprits or consequences: Understanding the metabolic dysregulation of muscle in diabetes. 2021 Sep 27 1
37 34692517 Counteracting Action of Curcumin on High Glucose-Induced Chemoresistance in Hepatic Carcinoma Cells. 2021 1
38 34790792 Sulfuretted hydrogen ameliorates high dose glucose-induced podocyte apoptosis via orchestrating AMPK/mTOR cascade-mediated anti-apoptotic effects. 2021 Oct 2
39 34839599 [The effect and mechanism of exosomes derived from human amniotic epithelial cells on the proliferation and migration of HaCaT in high glucose environment]. 2021 Dec 20 1
40 34938752 Differential Changes in Akt and AMPK Phosphorylation Regulating mTOR Activity in the Placentas of Pregnancies Complicated by Fetal Growth Restriction and Gestational Diabetes Mellitus With Large-For-Gestational Age Infants. 2021 1
41 34942999 Glucose Activates Lysine-Specific Demethylase 1 through the KEAP1/p62 Pathway. 2021 Nov 26 3
42 31448673 CAV1-CAVIN1-LC3B-mediated autophagy regulates high glucose-stimulated LDL transcytosis. 2020 Jun 1
43 31623699 Effect of glucose, soya oil and glutamine on protein expression and mammalian target of rapamycin complex 1 pathway of jejunal crypt enterocytes in weaned piglets. 2020 Mar 14 1
44 31698999 Glucose 6-Phosphate Accumulates via Phosphoglucose Isomerase Inhibition in Heart Muscle. 2020 Jan 3 1
45 31702491 miR-7 Reduces High Glucose Induced-damage Via HoxB3 and PI3K/AKT/mTOR Signaling Pathways in Retinal Pigment Epithelial Cells. 2020 1
46 31736063 Silencing of CD133 inhibits GLUT1-mediated glucose transport through downregulation of the HER3/Akt/mTOR pathway in colon cancer. 2020 Mar 1
47 31926252 Berberine mitigates high glucose-induced podocyte apoptosis by modulating autophagy via the mTOR/P70S6K/4EBP1 pathway. 2020 Feb 15 1
48 31942845 Research Progress of 70 kDa Ribosomal Protein S6 Kinase (P70S6K) Inhibitors as Effective Therapeutic Tools for Obesity, Type II Diabetes and Cancer. 2020 1
49 32058969 Exposure of Pancreatic β-Cells to Excess Glucose Results in Bimodal Activation of mTORC1 and mTOR-Dependent Metabolic Acceleration. 2020 Feb 21 3
50 32112869 Glucose availability regulates nicotinamide N-methyltransferase expression in adipocytes. 2020 May 1 1