3,9-bis((ethylthio)methyl)-K-252a

mitogen-activated protein kinase 8 ; Homo sapiens







10 Article(s)
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Title
Pub. Year
#Total Relationships
1 14744254 Mixed-lineage kinases: a target for the prevention of neurodegeneration. 2004 2
2 15019567 Inhibition of mixed lineage kinase 3 attenuates MPP+-induced neurotoxicity in SH-SY5Y cells. 2004 Apr 2 1
3 15023353 Targeting the JNK MAPK cascade for inhibition: basic science and therapeutic potential. 2004 Mar 11 2
4 15246824 Activation of c-Jun N-terminal kinase mediates gp120IIIB- and nucleoside analogue-induced sensory neuron toxicity. 2004 Aug 2
5 11756493 Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons. 2002 Jan 1 4
6 11788201 Blockade of c-Jun N-terminal kinase pathway attenuates gentamicin-induced cochlear and vestibular hair cell death. 2002 Jan 1
7 12062756 Blockade of c-Jun N-terminal kinase pathway attenuates gentamicin-induced cochlear and vestibular hair cell death. 2002 Apr 1
8 12388555 K252a and CEP1347 are neuroprotective compounds that inhibit mixed-lineage kinase-3 and induce activation of Akt and ERK. 2002 Dec 20 1
9 11331414 CEP-1347/KT-7515, an inhibitor of SAPK/JNK pathway activation, promotes survival and blocks multiple events associated with Abeta-induced cortical neuron apoptosis. 2001 May 2
10 10964950 Arsenite-induced apoptosis in cortical neurons is mediated by c-Jun N-terminal protein kinase 3 and p38 mitogen-activated protein kinase. 2000 Sep 1 1