Thapsigargin

mitogen-activated protein kinase 8 ; Homo sapiens







25 Article(s)
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1 34439364 The Unfolded Protein Response Is a Major Driver of LCN2 Expression in BCR-ABL- and JAK2V617F-Positive MPN. 2021 Aug 21 2
2 34446138 Stearoyl CoA Desaturase 1 and Inositol-Requiring Protein 1α Determine the Efficiency of Oleic Acid in Alleviating Silica Nanoparticle-Induced Insulin Resistance. 2021 Jul 1 1
3 32612030 [Citrus flavonoids as a target for the prevention of pancreatic β-cells dysfunction in diabetes.] 2020 1
4 31496655 Thapsigargin induces apoptosis in adrenocortical carcinoma by activating endoplasmic reticulum stress and the JNK signaling pathway: an in vitro and in vivo study. 2019 3
5 29531808 PLEKHN1 promotes apoptosis by enhancing Bax-Bak hetro-oligomerization through interaction with Bid in human colon cancer. 2018 Dec 1
6 26845695 The protective effect of lycopene on hypoxia/reoxygenation-induced endoplasmic reticulum stress in H9C2 cardiomyocytes. 2016 Mar 5 1
7 24961950 Endoplasmic reticulum stress-induced hepatic stellate cell apoptosis through calcium-mediated JNK/P38 MAPK and Calpain/Caspase-12 pathways. 2014 Sep 1
8 22864750 The regulatory mechanism of 4-phenylbutyric acid against ER stress-induced autophagy in human gingival fibroblasts. 2012 Jul 2
9 19782747 TNFalpha activation of PKCdelta, mediated by NFkappaB and ER stress, cross-talks with the insulin signaling cascade. 2010 Feb 1
10 19875701 JNK mitogen-activated protein kinase limits calcium-dependent chloride secretion across colonic epithelial cells. 2010 Jan 1
11 20447464 Nitric oxide induction of IRE1-alpha-dependent CREB phosphorylation in human glioma cells. 2010 Sep 15 2
12 20713550 Thapsigargin induces expression of activating transcription factor 3 in human keratinocytes involving Ca2+ ions and c-Jun N-terminal protein kinase. 2010 Nov 3
13 19139269 Endoplasmic reticulum stress-mediated autophagy/apoptosis induced by capsaicin (8-methyl-N-vanillyl-6-nonenamide) and dihydrocapsaicin is regulated by the extent of c-Jun NH2-terminal kinase/extracellular signal-regulated kinase activation in WI38 lung epithelial fibroblast cells. 2009 Apr 1
14 18544642 Effect of pioglitazone treatment on endoplasmic reticulum stress response in human adipose and in palmitate-induced stress in human liver and adipose cell lines. 2008 Aug 1
15 19010898 The mitogen-activated protein kinase phosphatase vaccinia H1-related protein inhibits apoptosis in prostate cancer cells and is overexpressed in prostate cancer. 2008 Nov 15 5
16 16124869 PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis. 2006 Jan 1 2
17 16357177 Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis. 2005 Dec 15 2
18 15115661 Gbetagamma signaling and Ca2+ mobilization co-operate synergistically in a Sos and Rac-dependent manner in the activation of JNK by Gq-coupled receptors. 2004 Jul 2
19 11850819 C-Jun N-terminal kinase is required for phorbol ester- and thapsigargin-induced apoptosis in the androgen responsive prostate cancer cell line LNCaP. 2002 Feb 7 7
20 11959861 A novel dual specificity phosphatase SKRP1 interacts with the MAPK kinase MKK7 and inactivates the JNK MAPK pathway. Implication for the precise regulation of the particular MAPK pathway. 2002 Jun 28 3
21 12358800 Endoplasmic reticulum calcium release is modulated by actin polymerization. 2002 Aug 1
22 10409755 Bcl-2 and Bcl-X(L) block thapsigargin-induced nitric oxide generation, c-Jun NH(2)-terminal kinase activity, and apoptosis. 1999 Aug 5
23 9067893 Endothelin-1 activates c-Jun NH2-terminal kinase in mesangial cells. 1997 Mar 1
24 9169474 Protein kinase C and protein kinase A inhibit calcium-dependent but not stress-dependent c-Jun N-terminal kinase activation in rat liver epithelial cells. 1997 Jun 6 1
25 7565768 Angiotensin II stimulates calcium-dependent activation of c-Jun N-terminal kinase. 1995 Nov 1