Metformin

mitogen-activated protein kinase 8 ; Homo sapiens







27 Article(s)
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1 32241082 Metformin enhances the cytotoxic effect of nilotinib and overcomes nilotinib resistance in chronic myeloid leukemia cells. 2021 Mar 2
2 33652909 Metformin Increases Survival in Hypopharyngeal Cancer Patients with Diabetes Mellitus: Retrospective Cohort Study and Cell-Based Analysis. 2021 Feb 26 1
3 34078517 Effects of different concentrations of metformin on osteoclast differentiation and apoptosis and its mechanism. 2021 Jun 1 3
4 31892847 Metformin induces cell cycle arrest, apoptosis and autophagy through ROS/JNK signaling pathway in human osteosarcoma. 2020 4
5 32021253 Metformin Inhibits Proliferation of Human Thyroid Cancer TPC-1 Cells by Decreasing LRP2 to Suppress the JNK Pathway. 2020 5
6 30760281 Low glucose and metformin-induced apoptosis of human ovarian cancer cells is connected to ASK1 via mitochondrial and endoplasmic reticulum stress-associated pathways. 2019 Feb 13 1
7 31233747 Effects of metformin on the heart with ischaemia-reperfusion injury: Evidence of its benefits from in vitro, in vivo and clinical reports. 2019 Sep 5 1
8 29148173 Metformin protects against intestinal barrier dysfunction via AMPKα1-dependent inhibition of JNK signalling activation. 2018 Jan 2
9 29630425 Suppressive effects of metformin on T-helper 1-related chemokines expression in the human monocytic leukemia cell line THP-1. 2018 Nov 1
10 29679571 Metformin ameliorates TGF-β1-induced osteoblastic differentiation of human aortic valve interstitial cells by inhibiting β-catenin signaling. 2018 Jun 7 1
11 30146065 Treatment-damaged hepatocellular carcinoma promotes activities of hepatic stellate cells and fibrosis through GDF15. 2018 Sep 15 1
12 30173657 The Role of SAPK/JNK Pathway in the Synergistic Effects of Metformin and Dacarbazine on Apoptosis in Raji and Ramos Lymphoma Cells. 2018 1
13 30333878 Metformin reverses the resistance mechanism of lung adenocarcinoma cells that knocks down the Nrf2 gene. 2018 Nov 3
14 28238946 Involvement of pregnane X receptor in the suppression of carboxylesterases by metformin in vivo and in vitro, mediated by the activation of AMPK and JNK signaling pathway. 2017 May 1 5
15 28927780 Effects of metformin on proliferation and apoptosis of human megakaryoblastic Dami and MEG-01 cells. 2017 Sep 2
16 26264935 Repurposing of metformin in liver injury: The JNK conundrum. 2016 Mar 1
17 26551514 Reply to "Repurposing of metformin in liver injury: The JNK conundrum". 2016 Mar 1
18 26939902 Metformin and AICAR regulate NANOG expression via the JNK pathway in HepG2 cells independently of AMPK. 2016 Aug 11
19 27403417 Metformin Alleviated Aβ-Induced Apoptosis via the Suppression of JNK MAPK Signaling Pathway in Cultured Hippocampal Neurons. 2016 7
20 27424158 Exenatide and metformin express their anti-inflammatory effects on human monocytes/macrophages by the attenuation of MAPKs and NFκB signaling. 2016 Oct 2
21 27562556 Editor's Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction. 2016 Dec 1
22 27569287 TRAIL restores DCA/metformin-mediated cell death in hypoxia. 2016 Sep 23 1
23 27904682 Targeting cancer cell metabolism: The combination of metformin and 2-Deoxyglucose regulates apoptosis in ovarian cancer cells via p38 MAPK/JNK signaling pathway. 2016 2
24 25245054 Metformin inhibits the invasion of human hepatocellular carcinoma cells and enhances the chemosensitivity to sorafenib through a downregulation of the ERK/JNK-mediated NF-κB-dependent pathway that reduces uPA and MMP-9 expression. 2014 Dec 4
25 21465524 Metformin sensitizes insulin signaling through AMPK-mediated PTEN down-regulation in preadipocyte 3T3-L1 cells. 2011 May 2
26 21895401 Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153. 2011 4
27 20590612 Metformin blocks migration and invasion of tumour cells by inhibition of matrix metalloproteinase-9 activation through a calcium and protein kinase Calpha-dependent pathway: phorbol-12-myristate-13-acetate-induced/extracellular signal-regulated kinase/activator protein-1. 2010 Jul 2