| 1 |
32404348 | Tob2 phosphorylation regulates global mRNA turnover to reshape transcriptome and impact cell proliferation. | 2020 Sep |
2 |
| 2 |
29052270 | Crystal structure of the human dual specificity phosphatase 1 catalytic domain. | 2018 Feb |
1 |
| 3 |
27392951 | Role of C-Jun N-terminal Kinase in Hepatocellular Carcinoma Development. | 2016 Dec |
2 |
| 4 |
25627174 | Analysis of insulin receptor substrate signaling dynamics on microstructured surfaces. | 2015 Mar |
1 |
| 5 |
24699331 | Regulation of hepatic insulin receptor activity following injury. | 2014 May 15 |
2 |
| 6 |
25341038 | JNK-NQO1 axis drives TAp73-mediated tumor suppression upon oxidative and proteasomal stress. | 2014 Oct 23 |
1 |
| 7 |
25353341 | Phosphorylation of sterol regulatory element-binding protein (SREBP)-1c by p38 kinases, ERK and JNK influences lipid metabolism and the secretome of human liver cell line HepG2. | 2014 Dec |
1 |
| 8 |
21660049 | A critical step for JNK activation: isomerization by the prolyl isomerase Pin1. | 2012 Jan |
11 |
| 9 |
22156573 | A persistent stress response to impeded axonal transport leads to accumulation of amyloid-β in the endoplasmic reticulum, and is a probable cause of sporadic Alzheimer's disease. | 2012 |
2 |
| 10 |
21030692 | JNK regulates binding of alpha-catenin to adherens junctions and cell-cell adhesion. | 2011 Feb |
2 |
| 11 |
21040800 | Chronic treatment with epoxyeicosatrienoic acids modulates insulin signaling and prevents insulin resistance in hepatocytes. | 2011 Feb |
2 |
| 12 |
21463260 | Phosphorylation of JDP2 on threonine-148 by the c-Jun N-terminal kinase targets it for proteosomal degradation. | 2011 Jun 15 |
1 |
| 13 |
21777610 | Phosphorylation of threonine 190 is essential for nuclear localization and endocytosis of the FTS (Fused Toes Homolog) protein. | 2011 Nov 1 |
1 |
| 14 |
21856198 | JNK1 phosphorylation of Cdt1 inhibits recruitment of HBO1 histone acetylase and blocks replication licensing in response to stress. | 2011 Oct 7 |
1 |
| 15 |
20156194 | Filamin associates with stress signalling kinases MKK7 and MKK4 and regulates JNK activation. | 2010 Mar 29 |
2 |
| 16 |
20649571 | 2-Phenyl-5-(pyrrolidin-1-yl)-1-(3,4,5-trimethoxybenzyl)-1H-benzimidazole, a benzimidazole derivative, inhibits growth of human prostate cancer cells by affecting tubulin and c-Jun N-terminal kinase. | 2010 Aug |
1 |
| 17 |
19651615 | Control of p53 multimerization by Ubc13 is JNK-regulated. | 2009 Aug 4 |
1 |
| 18 |
19667122 | JNK phosphorylates beta-catenin and regulates adherens junctions. | 2009 Nov |
1 |
| 19 |
17602798 | 3D-QSAR and docking studies of aminopyridine carboxamide inhibitors of c-Jun N-terminal kinase-1. | 2008 Mar |
2 |
| 20 |
17920329 | Negative charged threonine 95 of c-Jun is essential for c-Jun N-terminal kinase-dependent phosphorylation of threonine 91/93 and stress-induced c-Jun biological activity. | 2008 |
1 |
| 21 |
18201741 | The contribution of c-Jun N-terminal kinase activation and subsequent Bcl-2 phosphorylation to apoptosis induction in human B-cells is dependent on the mode of action of specific stresses. | 2008 Apr 1 |
1 |
| 22 |
18469002 | Phosphorylation of Bad at Thr-201 by JNK1 promotes glycolysis through activation of phosphofructokinase-1. | 2008 Jul 25 |
3 |
| 23 |
18553930 | Phosphorylation of protein phosphatase 2Czeta by c-Jun NH2-terminal kinase at Ser92 attenuates its phosphatase activity. | 2008 Jul 8 |
1 |
| 24 |
18667537 | Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin. | 2008 Oct |
1 |
| 25 |
17665439 | Fractalkine is a novel chemoattractant for rheumatoid arthritis fibroblast-like synoviocyte signaling through MAP kinases and Akt. | 2007 Aug |
1 |
| 26 |
16442502 | Cloning and expression of human mitogen-activated protein kinase kinase 7gamma1. | 2006 Mar 17 |
2 |
| 27 |
16772869 | Formation of phospho-SAPK/JNK granules in the hippocampus is an early event in Alzheimer disease. | 2006 May |
1 |
| 28 |
15743762 | c-Jun N-terminal kinase (JNK) positively regulates NFATc2 transactivation through phosphorylation within the N-terminal regulatory domain. | 2005 May 27 |
2 |
| 29 |
15805466 | The nucleolus as a stress sensor: JNK2 inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis. | 2005 Apr 15 |
3 |
| 30 |
16238095 | Role of the phosphatase PP4 in the activation of JNK-1 in prostate carcinoma cell lines PC-3 and LNCaP resulting in increased AP-1 and EGR-1 activity. | 2005 |
2 |
| 31 |
14967141 | JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD. | 2004 Feb 13 |
1 |
| 32 |
14970211 | Facilitation of stress-induced phosphorylation of beta-amyloid precursor protein family members by X11-like/Mint2 protein. | 2004 May 14 |
2 |
| 33 |
15105425 | Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK. | 2004 Jun 25 |
2 |
| 34 |
15304498 | Degradation of the apical sodium-dependent bile acid transporter by the ubiquitin-proteasome pathway in cholangiocytes. | 2004 Oct 22 |
2 |
| 35 |
15538382 | FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK. | 2004 Dec 8 |
2 |
| 36 |
15610029 | Phosphoregulation of mixed-lineage kinase 1 activity by multiple phosphorylation in the activation loop. | 2004 Dec 28 |
1 |
| 37 |
12624093 | Different properties of SEK1 and MKK7 in dual phosphorylation of stress-induced activated protein kinase SAPK/JNK in embryonic stem cells. | 2003 May 9 |
8 |
| 38 |
12665528 | A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1. | 2003 Jun 20 |
1 |
| 39 |
12756254 | Recruitment of JNK to JIP1 and JNK-dependent JIP1 phosphorylation regulates JNK module dynamics and activation. | 2003 Aug 1 |
2 |
| 40 |
12758252 | Detection of JNK and p38 activation by flow cytometry analysis. | 2003 Jun 15 |
1 |
| 41 |
12853483 | JNK phosphorylation relieves HDAC3-dependent suppression of the transcriptional activity of c-Jun. | 2003 Jul 15 |
1 |
| 42 |
12917434 | Amyloid beta protein precursor is phosphorylated by JNK-1 independent of, yet facilitated by, JNK-interacting protein (JIP)-1. | 2003 Oct 24 |
1 |
| 43 |
11912189 | Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade. | 2002 May 31 |
1 |
| 44 |
11948414 | Hepatocyte growth factor/scatter factor activates the ETS1 transcription factor by a RAS-RAF-MEK-ERK signaling pathway. | 2002 Apr 4 |
1 |
| 45 |
12223490 | Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress. | 2002 Nov 15 |
1 |
| 46 |
12225289 | Differential targeting of the stress mitogen-activated protein kinases to the c-Jun dimerization protein 2. | 2002 Dec 15 |
2 |
| 47 |
11283254 | Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress. | 2001 Apr |
1 |
| 48 |
11418587 | Impaired synergistic activation of stress-activated protein kinase SAPK/JNK in mouse embryonic stem cells lacking SEK1/MKK4: different contribution of SEK2/MKK7 isoforms to the synergistic activation. | 2001 Aug 17 |
3 |
| 49 |
11062067 | Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7. | 2000 Nov 15 |
4 |
| 50 |
9891090 | The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases. | 1999 Feb |
1 |