Acetaminophen

mitogen-activated protein kinase 8 ; Homo sapiens







23 Article(s)
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1 35145060 Genetic and pharmacological inhibition of XBP1 protects against APAP hepatotoxicity through the activation of autophagy. 2022 Feb 10 2
2 35624743 DDAH1 Protects against Acetaminophen-Induced Liver Hepatoxicity in Mice. 2022 Apr 29 1
3 32617995 Letter to the Editor: Does c-Jun N-Terminal Kinase Regulate Acetaminophen Hepatotoxicity by Modulating Nuclear Factor Erythroid 2-Related Factor 2-Dependent Genes or Mitochondrial Oxidant Stress? 2021 Jan 1
4 33959992 Drug-induced liver injury: Oltipraz and C2-ceramide intervene HNF-1α/GSTA1 expression via JNK signaling pathway. 2021 Dec 2
5 33983442 Spatial Reconstruction of the Early Hepatic Transcriptomic Landscape After an Acetaminophen Overdose Using Single-Cell RNA-Sequencing. 2021 Aug 3 1
6 30630510 Corilagin alleviates acetaminophen-induced hepatotoxicity via enhancing the AMPK/GSK3β-Nrf2 signaling pathway. 2019 Jan 10 2
7 30974967 Thymoquinone Attenuates Acetaminophen Overdose-Induced Acute Liver Injury and Inflammation Via Regulation of JNK and AMPK Signaling Pathway. 2019 1
8 31212128 Mangiferin ameliorates acetaminophen-induced hepatotoxicity through APAP-Cys and JNK modulation. 2019 Sep 1
9 29739258 4-Methylpyrazole protects against acetaminophen hepatotoxicity in mice and in primary human hepatocytes. 2018 Dec 3
10 26998291 Sensitivity of ovarian cancer cells to acetaminophen reveals biological pathways that affect patient survival. 2016 Mar 2
11 27165078 p53- and Caspase-3-Independent Mechanism of Acetaminophen Effect on Human Neural Cells. 2016 Apr 1
12 27375192 Mechanisms of Acetaminophen Hepatotoxicity: Do We Need JNK for Cell Death? 2016 Aug 1
13 27562556 Editor's Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction. 2016 Dec 2
14 26190663 Pathophysiological significance of c-jun N-terminal kinase in acetaminophen hepatotoxicity. 2015 1
15 24492462 Evaluation of three-dimensional cultured HepG2 cells in a nano culture plate system: an in vitro human model of acetaminophen hepatotoxicity. 2014 2
16 24905542 Mechanisms of acetaminophen-induced cell death in primary human hepatocytes. 2014 Sep 15 1
17 25204659 Essential role of protein-tyrosine phosphatase 1B in the modulation of insulin signaling by acetaminophen in hepatocytes. 2014 Oct 17 1
18 19931551 BGP-15 inhibits caspase-independent programmed cell death in acetaminophen-induced liver injury. 2010 Feb 15 1
19 20166895 Acetaminophen induced acute liver failure via oxidative stress and JNK activation: protective role of taurine by the suppression of cytochrome P450 2E1. 2010 Mar 3
20 20423716 c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity. 2010 Jul 5
21 17185352 Critical role of c-jun (NH2) terminal kinase in paracetamol- induced acute liver failure. 2007 Jul 2
22 16979204 Leflunomide or A77 1726 protect from acetaminophen-induced cell injury through inhibition of JNK-mediated mitochondrial permeability transition in immortalized human hepatocytes. 2006 Nov 15 2
23 11562448 Acetaminophen induces apoptosis of C6 glioma cells by activating the c-Jun NH(2)-terminal protein kinase-related cell death pathway. 2001 Oct 4