Oxysterols

smoothened, frizzled class receptor ; Homo sapiens







10 Article(s)
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Pub. Year
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1 34111427 Sterol regulation of developmental and oncogenic Hedgehog signaling. 2022 Feb 1
2 32855528 ABT-199 inhibits Hedgehog pathway by acting as a competitive inhibitor of oxysterol, rather as a BH3 mimetic. 2021 Jun 1
3 34440907 Mechanisms of Smoothened Regulation in Hedgehog Signaling. 2021 Aug 20 1
4 31137846 Inhibition of Hedgehog Signaling in Fibroblasts, Pancreatic, and Lung Tumor Cells by Oxy186, an Oxysterol Analogue with Drug-Like Properties. 2019 May 27 1
5 31168089 Cryo-EM structure of oxysterol-bound human Smoothened coupled to a heterotrimeric Gi. 2019 Jul 1
6 27490478 Inhibition of Pancreatic Cancer Cell-Induced Paracrine Hedgehog Signaling by Liver X Receptor Agonists and Oxy16, a Naturally Occurring Oxysterol. 2017 Mar 2
7 23831757 Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling. 2013 Sep 8
8 23954590 Hedgehog pathway modulation by multiple lipid binding sites on the smoothened effector of signal response. 2013 Aug 26 3
9 24171105 Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling. 2013 Oct 29 4
10 16707575 Oxysterols stimulate Sonic hedgehog signal transduction and proliferation of medulloblastoma cells. 2006 May 30 3