gemcitabine

poly(ADP-ribose) polymerase 1 ; Homo sapiens







30 Article(s)
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1 33468723 [Effects of Olaparib, a PARP-1 Inhibitor, on Triple Negative Breast Cancer Cells with a BRCA1 Mutation]. 2021 Jan 1
2 33552258 MicroRNA-7 modulates cellular senescence to relieve gemcitabine resistance by targeting PARP1/NF-κB signaling in pancreatic cancer cells. 2021 Feb 3
3 33975311 The Impact of Platinum-Containing Chemotherapies in Advanced Triple-Negative Breast Cancer: Meta-Analytical Approach to Evaluating Its Efficacy and Safety. 2021 1
4 34201963 Gemcitabine-Based Chemoradiotherapy Enhanced by a PARP Inhibitor in Pancreatic Cancer Cell Lines. 2021 Jun 25 1
5 31802375 Combination of a novel microtubule inhibitor MBRI-001 and gemcitabine synergistically induces cell apoptosis by increasing DNA damage in pancreatic cancer cell lines. 2020 Oct 1
6 31989039 CRISPR/Cas9-mediated mutagenesis to validate the synergy between PARP1 inhibition and chemotherapy in BRCA1-mutated breast cancer cells. 2020 Jan 1
7 30152517 PARP inhibitors synergize with gemcitabine by potentiating DNA damage in non-small-cell lung cancer. 2019 Mar 1 2
8 31807190 The modulation study of multiple drug resistance in bladder cancer by curcumin and resveratrol. 2019 Dec 2
9 28176879 PARP inhibitor increases chemosensitivity by upregulating miR-664b-5p in BRCA1-mutated triple-negative breast cancer. 2017 Feb 8 2
10 28394191 The PARP inhibitor olaparib enhances the cytotoxicity of combined gemcitabine, busulfan and melphalan in lymphoma cells. 2017 Nov 1
11 28770300 Phase I study of veliparib in combination with gemcitabine. 2017 Sep 1
12 29048622 Enhancement of cytotoxic effects of gemcitabine by Dclk1 inhibition through suppression of Chk1 phosphorylation in human pancreatic cancer cells. 2017 Nov 1
13 26677013 Survivin silencing and TRAIL expression using oncolytic adenovirus increase anti-tumorigenic activity in gemcitabine-resistant pancreatic cancer cells. 2016 Mar 2
14 27035235 Suppression of STAT5b in pancreatic cancer cells leads to attenuated gemcitabine chemoresistance, adhesion and invasion. 2016 Jun 1
15 25572120 Expression of oncogenic HMGN5 increases the sensitivity of prostate cancer cells to gemcitabine. 2015 Mar 1
16 26028101 In vitro Study of the Antagonistic Effect of Low-dose Liquiritigenin on Gemcitabine-induced Capillary Leak Syndrome in Pancreatic Adenocarcinoma via Inhibiting ROS- Mediated Signalling Pathways. 2015 2
17 24607283 PARP inhibitors in ovarian cancer: current status and future promise. 2014 May 1
18 25202071 Decreased miR-206 expression in BRCA1 wild-type triple-negative breast cancer cells after concomitant treatment with gemcitabine and a Poly(ADP-ribose) polymerase-1 inhibitor. 2014 Sep 1
19 25271986 Gemcitabine induces poly (ADP-ribose) polymerase-1 (PARP-1) degradation through autophagy in pancreatic cancer. 2014 2
20 23898224 Inhibition of SIRT1 combined with gemcitabine therapy for pancreatic carcinoma. 2013 2
21 23047891 BMS-754807, a small-molecule inhibitor of insulin-like growth factor-1 receptor/insulin receptor, enhances gemcitabine response in pancreatic cancer. 2012 Dec 1
22 21368455 [PARP inhibitors for cancer therapy]. 2011 Jan 1
23 21777194 The emerging role of poly(ADP-Ribose) polymerase inhibitors in cancer treatment. 2011 Dec 1
24 20798217 Synergistic chemosensitivity of triple-negative breast cancer cell lines to poly(ADP-Ribose) polymerase inhibition, gemcitabine, and cisplatin. 2010 Oct 15 1
25 20940192 Association of DNA repair gene polymorphisms with response to platinum-based doublet chemotherapy in patients with non-small-cell lung cancer. 2010 Nov 20 2
26 20495713 Proteasome inhibition enhances antitumour effects of gemcitabine in experimental pancreatic cancer. 2009 Nov 2
27 18572621 Improved in vitro anti-tumoral activity, intracellular uptake and apoptotic induction of gemcitabine-loaded pegylated unilamellar liposomes. 2008 Apr 1
28 17444865 Combination therapy of poly (ADP-ribose) polymerase inhibitor 3-aminobenzamide and gemcitabine shows strong antitumor activity in pancreatic cancer cells. 2007 May 1
29 16505115 c-Abl-independent p73 stabilization during gemcitabine- or 4'-thio-beta-D-arabinofuranosylcytosine-induced apoptosis in wild-type and p53-null colorectal cancer cells. 2006 Feb 1
30 15726400 Apoptosis by gemcitabine in non-small cell lung cancer cell line KNS62 is induced downstream of caspase 8 and is profoundly blocked by Bcl-xL over-expression. 2005 Jun 1