2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one

poly(ADP-ribose) polymerase 1 ; Homo sapiens







20 Article(s)
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Pub. Year
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1 34958867 Therapeutic potential of the PI3K inhibitor LY294002 and PARP inhibitor Talazoparib combination in BRCA-deficient triple negative breast cancer cells. 2022 Mar 1
2 32581555 Salinomycin and Sulforaphane Exerted Synergistic Antiproliferative and Proapoptotic Effects on Colorectal Cancer Cells by Inhibiting the PI3K/Akt Signaling Pathway in vitro and in vivo. 2020 1
3 28677724 TNFR2 promotes Adriamycin resistance in breast cancer cells by repairing DNA damage. 2017 Sep 1
4 25638174 Luteolin exerts a marked antitumor effect in cMet-overexpressing patient-derived tumor xenograft models of gastric cancer. 2015 Feb 1 1
5 25821107 PI3K/AKT pathway-mediated regulation of p27(Kip1) is associated with cell cycle arrest and apoptosis in cervical cancer. 2015 Jun 2
6 26043797 MHY218-induced apoptotic cell death is enhanced by the inhibition of autophagy in AGS human gastric cancer cells. 2015 Aug 1
7 26075254 Deguelin induces apoptosis by targeting both EGFR-Akt and IGF1R-Akt pathways in head and neck squamous cell cancer cell lines. 2015 2
8 24841907 Isoorientin induces apoptosis and autophagy simultaneously by reactive oxygen species (ROS)-related p53, PI3K/Akt, JNK, and p38 signaling pathways in HepG2 cancer cells. 2014 Jun 11 2
9 23386415 Inhibition of p21 and Akt potentiates SU6656-induced caspase-independent cell death in FRO anaplastic thyroid carcinoma cells. 2013 Jun 1
10 22226932 Role of autophagy in chemoresistance: regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA-PKcs and PARP-1. 2012 Mar 15 1
11 21048307 Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway. 2010 1
12 19426673 PARP-1 inhibition-induced activation of PI-3-kinase-Akt pathway promotes resistance to taxol. 2009 Apr 15 1
13 18425342 Constitutive activation of p70 S6 kinase is associated with intrinsic resistance to cisplatin. 2008 May 2
14 16267832 Synergistic interaction between 17-AAG and phosphatidylinositol 3-kinase inhibition in human malignant glioma cells. 2006 Jan 1
15 16337154 Critical role of PI3-kinase/Akt activation in the PARP inhibitor induced heart function recovery during ischemia-reperfusion. 2006 Feb 14 1
16 19771269 Augmentation of sodium butyrate-induced apoptosis by phosphatidylinositol 3-kinase inhibition in the human cervical cancer cell-line. 2006 Apr 2
17 14747535 Latent membrane protein 2A inhibits transforming growth factor-beta 1-induced apoptosis through the phosphatidylinositol 3-kinase/Akt pathway. 2004 Feb 1
18 12890489 PI3K inhibitors changed the p53-induced response of Saos-2 cells from growth arrest to apoptosis. 2003 Aug 15 1
19 12060639 Augmentation of sodium butyrate-induced apoptosis by phosphatidylinositol 3'-kinase inhibition in the KM20 human colon cancer cell line. 2002 Jun 1
20 10362360 Etk/Bmx, a PH-domain containing tyrosine kinase, protects prostate cancer cells from apoptosis induced by photodynamic therapy or thapsigargin. 1999 Jun 3 1