Paclitaxel

poly(ADP-ribose) polymerase 1 ; Homo sapiens







66 Article(s)
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1 34856211 A natural product, voacamine, sensitizes paclitaxel-resistant human ovarian cancer cells. 2022 Jan 1 1
2 34861374 Veliparib monotherapy following carboplatin/paclitaxel plus veliparib combination therapy in patients with germline BRCA-associated advanced breast cancer: results of exploratory analyses from the phase III BROCADE3 trial. 2022 Mar 1
3 35281113 Applicability of Anticancer Drugs for the Triple-Negative Breast Cancer Based on Homologous Recombination Repair Deficiency. 2022 1
4 33300063 WWOX promotes apoptosis and inhibits autophagy in paclitaxel‑treated ovarian carcinoma cells. 2021 Feb 3
5 33894017 A Population Pharmacokinetic Meta-Analysis of Veliparib, a PARP Inhibitor, Across Phase 1/2/3 Trials in Cancer Patients. 2021 Sep 1
6 34435645 Proteasome inhibitors decrease paclitaxel‑induced cell death in nasopharyngeal carcinoma with the accumulation of CDK1/cyclin B1. 2021 Oct 1
7 34768915 Ursolic Acid Accelerates Paclitaxel-Induced Cell Death in Esophageal Cancer Cells by Suppressing Akt/FOXM1 Signaling Cascade. 2021 Oct 25 1
8 32554905 CRISPR-mediated knockdown of miR-214 modulates cell fate in response to anti-cancer drugs in HPV-negative and HPVpositive cervical cancer cells. 2020 1
9 32594311 The Prognostic Value of PARP Expression in High-Grade Epithelial Ovarian Cancer. 2020 Oct 1
10 32594651 Paclitaxel induces apoptosis through the TAK1-JNK activation pathway. 2020 Aug 1
11 33336070 A review of current progress in triple-negative breast cancer therapy. 2020 1
12 30592172 Paclitaxel Induce Apoptosis of Giant Cells Tumor of Bone via TP53INP1 Signaling. 2019 Feb 2
13 31295843 Inhibition of Phosphatidylinositol 3-kinase (PI3K) Signaling Synergistically Potentiates Antitumor Efficacy of Paclitaxel and Overcomes Paclitaxel-Mediated Resistance in Cervical Cancer. 2019 Jul 10 1
14 30066930 Curcumin and paclitaxel induce cell death in breast cancer cell lines. 2018 Oct 1
15 27716527 Nanomedicine-based paclitaxel induced apoptotic signaling pathways in A562 leukemia cancer cells. 2017 Jan 1 1
16 28454476 PARP inhibition sensitizes endometrial cancer cells to paclitaxel-induced apoptosis. 2017 Apr 2
17 28473236 Superior antitumor effect of extremely high drug loading self-assembled paclitaxel nanofibers. 2017 Jun 30 1
18 28639112 Kuguacin J isolated from bitter melon leaves modulates paclitaxel sensitivity in drug-resistant human ovarian cancer cells. 2017 Oct 1
19 26985944 Paclitaxel induces apoptosis in leukemia cells through a JNK activation-dependent pathway. 2016 Mar 11 3
20 27312786 Neuroglobin overexpression induced by the 17β-Estradiol-Estrogen receptor-α Pathway reduces the sensitivity of MCF-7 Breast cancer cell to paclitaxel. 2016 Aug 1
21 27840924 Basic helix-loop-helix transcription factor DEC2 functions as an anti-apoptotic factor during paclitaxel-induced apoptosis in human prostate cancer cells. 2016 Dec 5
22 27994465 Polyethylenimine-functionalized silver nanoparticle-based co-delivery of paclitaxel to induce HepG2 cell apoptosis. 2016 1
23 29879343 [Olaparib potentiates the antitumor effect of Taxol on 4T1 breast cancer]. 2016 Jun 1
24 25633416 3,3'-Diindolylmethane potentiates paclitaxel-induced antitumor effects on gastric cancer cells through the Akt/FOXM1 signaling cascade. 2015 Apr 2
25 24247637 Combination treatment with paclitaxel and doxorubicin inhibits growth of human esophageal squamous cancer cells by inactivation of Akt. 2014 Jan 1
26 24520227 Synergistic Effect of COX-2 Inhibitor on Paclitaxel-Induced Apoptosis in the Human Ovarian Cancer Cell Line OVCAR-3. 2014 Jan 1
27 24826054 PARP inhibitor reduces proliferation and increases apoptosis in breast cancer cells. 2014 Apr 1
28 23286491 Effect of trichostatin A and paclitaxel on the proliferation and apoptosis of lung adenocarcinoma cells. 2013 Jan 1
29 23460921 Superior antitumor activity of nanoparticle albumin-bound paclitaxel in experimental gastric cancer. 2013 1
30 23474708 Inhibition of Hec1 expression enhances the sensitivity of human ovarian cancer cells to paclitaxel. 2013 Apr 1
31 23875078 Selective cyclooxygenase inhibitors increase paclitaxel sensitivity in taxane-resistant ovarian cancer by suppressing P-glycoprotein expression. 2013 Jul 1
32 24137360 Synergy of Taxol and rhein lysinate associated with the downregulation of ERK activation in lung carcinoma cells. 2013 Aug 2
33 24168763 Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer. 2013 2
34 22543280 GRP78 induced by estrogen plays a role in the chemosensitivity of endometrial cancer. 2012 Jul 1
35 22642877 Mifepristone prevents repopulation of ovarian cancer cells escaping cisplatin-paclitaxel therapy. 2012 Jun 22 1
36 22895534 Adenoviral neutral endopeptidase gene delivery in combination with paclitaxel for the treatment of prostate cancer. 2012 Oct 1
37 22967465 [Effect of trichostatin A and paclitaxel on the growth and apoptosis of lung adenocarcinoma cell lines]. 2012 Jul 1
38 23023313 Taxol-induced growth arrest and apoptosis is associated with the upregulation of the Cdk inhibitor, p21WAF1/CIP1, in human breast cancer cells. 2012 Dec 2
39 20665703 ZD6474 enhances paclitaxel antiproliferative and apoptotic effects in breast carcinoma cells. 2011 Feb 1
40 21327324 Basic helix-loop-helix transcription factors DEC1 and DEC2 regulate the paclitaxel-induced apoptotic pathway of MCF-7 human breast cancer cells. 2011 Apr 2
41 21469749 The key residues of active sites on the catalytic fragment for paclitaxel interacting with poly (ADP-ribose) polymerase. 2011 Jun 9
42 21546083 Role of cellular uptake in the reversal of multidrug resistance by PEG-b-PLA polymeric micelles. 2011 Aug 12
43 21935570 Deciphering the role of paclitaxel in the SKGT4 human esophageal adenocarcinoma cell line. 2011 Dec 1
44 20498641 Elevated expression of erbB3 confers paclitaxel resistance in erbB2-overexpressing breast cancer cells via upregulation of Survivin. 2010 Jul 22 2
45 20940192 Association of DNA repair gene polymorphisms with response to platinum-based doublet chemotherapy in patients with non-small-cell lung cancer. 2010 Nov 20 2
46 19424586 Synergistic interaction between tetra-arsenic oxide and paclitaxel in human cancer cells in vitro. 2009 Jun 1
47 19426673 PARP-1 inhibition-induced activation of PI-3-kinase-Akt pathway promotes resistance to taxol. 2009 Apr 15 6
48 19561399 Alpha-tocopheryl succinate potentiates the paclitaxel-induced apoptosis through enforced caspase 8 activation in human H460 lung cancer cells. 2009 Oct 31 2
49 18710614 [Effects of trichostatin A and paclitaxel on apoptosis and mitochondrial membrane potential of human endometrial carcinoma Ark2 cells]. 2008 Aug 2
50 18986507 Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer. 2008 2