Acetylcysteine

poly(ADP-ribose) polymerase 1 ; Homo sapiens







41 Article(s)
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1 33819738 Novel ginsenoside derivatives have shown their effects on PC-3 cells by inducing G1-phase arrest and reactive oxygen species-mediate cell apoptosis. 2021 Jul 1
2 34204067 Hydroquinone Induces NLRP3-Independent IL-18 Release from ARPE-19 Cells. 2021 Jun 6 2
3 28681938 ω-hydroxyundec-9-enoic acid induces apoptosis by ROS mediated JNK and p38 phosphorylation in breast cancer cell lines. 2018 Jan 2
4 29642488 Sinularin Selectively Kills Breast Cancer Cells Showing G2/M Arrest, Apoptosis, and Oxidative DNA Damage. 2018 Apr 8 2
5 29684820 Increased oxidative stress mediates the antitumor effect of PARP inhibition in ovarian cancer. 2018 Jul 2
6 29876988 Reactive oxygen species-mediated phosphorylation of p38 signaling is critically involved in apoptotic effect of Tanshinone I in colon cancer cells. 2018 Oct 1
7 30597845 MHY440, a Novel Topoisomerase Ι Inhibitor, Induces Cell Cycle Arrest and Apoptosis via a ROS-Dependent DNA Damage Signaling Pathway in AGS Human Gastric Cancer Cells. 2018 Dec 28 1
8 27539140 Suppression of reactive oxygen species-mediated ERK and JNK activation sensitizes dihydromyricetin-induced mitochondrial apoptosis in human non-small cell lung cancer. 2017 Apr 1
9 28087840 Vibrio cholerae Cholix Toxin-Induced HepG2 Cell Death is Enhanced by Tumor Necrosis Factor-Alpha Through ROS and Intracellular Signal-Regulated Kinases. 2017 Apr 1 2
10 28653879 TP53 alteration determines the combinational cytotoxic effect of doxorubicin and an antioxidant NAC. 2017 Jun 1
11 28731136 MHY451 induces cell cycle arrest and apoptosis by ROS generation in HCT116 human colorectal cancer cells. 2017 Sep 1
12 25972196 The role of NF-κB in PARP-inhibitor-mediated sensitization and detoxification of arsenic trioxide in hepatocellular carcinoma cells. 2015 Jun 1
13 27103891 Trans-1,3-diphenyl-2,3-epoxypropan-1-one, a chalcone derivative, induces apoptosis via ROS-mediated down-regulation of Bcl-xL in human leukemia HL-60 cells. 2015 1
14 23640957 Reactive oxygen species-mediated activation of AMP-activated protein kinase and c-Jun N-terminal kinase plays a critical role in beta-sitosterol-induced apoptosis in multiple myeloma U266 cells. 2014 Mar 1
15 23765509 Induction of G2/M phase arrest and apoptosis by the flavonoid tamarixetin on human leukemia cells. 2014 Dec 1
16 24481553 Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells. 2014 Apr 1
17 24586814 The pentachlorophenol metabolite tetrachlorohydroquinone induces massive ROS and prolonged p-ERK expression in splenocytes, leading to inhibition of apoptosis and necrotic cell death. 2014 2
18 24870979 Trivalent methylated arsenic metabolites induce apoptosis in human myeloid leukemic HL-60 cells through generation of reactive oxygen species. 2014 Aug 2
19 23114871 Ovarian cancer cells, not normal cells, are damaged by Mirk/Dyrk1B kinase inhibition. 2013 May 15 2
20 23267148 ROS mediate proapoptotic and antisurvival activity of oleanane triterpenoid CDDO-Me in ovarian cancer cells. 2013 Jan 2
21 23518073 Generation of reactive oxygen species by a novel berberine-bile acid analog mediates apoptosis in hepatocarcinoma SMMC-7721 cells. 2013 Apr 19 2
22 24041743 OSU-A9, an indole-3-carbinol derivative, induces cytotoxicity in acute myeloid leukemia through reactive oxygen species-mediated apoptosis. 2013 Nov 15 1
23 22694287 Isoliquiritigenin treatment induces apoptosis by increasing intracellular ROS levels in HeLa cells. 2012 1
24 22946344 Inhibition of cell proliferation and induction of apoptosis by CDDO-Me in pancreatic cancer cells is ROS-dependent. 2012 1
25 21532338 Oral RKS262 reduces tumor burden in a neuroblastoma xenograft animal model and mediates cytotoxicity through SAPK/JNK and ROS activation in vitro. 2011 Jun 15 2
26 19782051 Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells through a ROS-dependent mechanism. 2010 Feb 1 1
27 20594983 Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway. 2010 Sep 1
28 20981856 Acrylonitrile induced apoptosis via oxidative stress in neuroblastoma SH-SY5Y cell. 2010 Oct 2
29 21113238 Depleting Mirk Kinase Increases Cisplatin Toxicity in Ovarian Cancer Cells. 2010 Aug 1 1
30 19153832 N-acetyl cysteine enhances imatinib-induced apoptosis of Bcr-Abl+ cells by endothelial nitric oxide synthase-mediated production of nitric oxide. 2009 Mar 1
31 19409983 Manumycin inhibits STAT3, telomerase activity, and growth of glioma cells by elevating intracellular reactive oxygen species generation. 2009 Aug 15 1
32 17786977 Direct current electrical fields induce apoptosis in oral mucosa cancer cells by NADPH oxidase-derived reactive oxygen species. 2008 Jan 2
33 18443432 Sustained ERK activation is involved in the kaempferol-induced apoptosis of breast cancer cells and is more evident under 3-D culture condition. 2008 Jul 1
34 17237268 Combination treatment with arsenic trioxide and phytosphingosine enhances apoptotic cell death in arsenic trioxide-resistant cancer cells. 2007 Jan 1
35 17428624 Protein tyrosine nitration and poly(ADP-ribose) polymerase activation in N-methyl-N-nitro-N-nitrosoguanidine-treated thymocytes: implication for cytotoxicity. 2007 May 15 1
36 16039951 The heterocyclic ruthenium(III) complex KP1019 (FFC14A) causes DNA damage and oxidative stress in colorectal tumor cells. 2005 Aug 26 1
37 12850239 Involvement of hydrogen peroxide in mistletoe lectin-II-induced apoptosis of myeloleukemic U937 cells. 2003 Jul 25 2
38 12860476 Effect of fraxetin and myricetin on rotenone-induced cytotoxicity in SH-SY5Y cells: comparison with N-acetylcysteine. 2003 Jul 4 1
39 11707430 Methylglyoxal enhances cisplatin-induced cytotoxicity by activating protein kinase Cdelta. 2002 Jan 25 1
40 10652256 4-hydroxynonenal induces a cellular redox status-related activation of the caspase cascade for apoptotic cell death. 2000 Feb 1
41 9457054 U937 apoptotic cell death by nitric oxide: Bcl-2 downregulation and caspase activation. 1998 Jan 10 1