Hydrogen Peroxide

poly(ADP-ribose) polymerase 1 ; Homo sapiens







142 Article(s)
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1 34989943 A novel antagonist of TRPM2 and TRPV4 channels: Carvacrol. 2022 Mar 1
2 35410407 NAMPT-dependent NAD+ salvage is crucial for the decision between apoptotic and necrotic cell death under oxidative stress. 2022 Apr 11 1
3 33378949 Protective effects of PARP1-inhibitory compound in dry age-related macular degeneration. 2021 Jan 1
4 33838689 Effect of Shuangdan Mingmu capsule, a Chinese herbal formula, on oxidative stress-induced apoptosis of pericytes through PARP/GAPDH pathway. 2021 Apr 10 3
5 34481495 A self-amplified nanocatalytic system for achieving "1 + 1 + 1 > 3" chemodynamic therapy on triple negative breast cancer. 2021 Sep 4 4
6 34572083 Preclinical Studies on the Effect of Rucaparib in Ovarian Cancer: Impact of BRCA2 Status. 2021 Sep 15 1
7 34839666 Dual Imaging of Poly(ADP-ribose) Polymerase-1 and Endogenous H2O2 for the Diagnosis of Cancer Cells Using Silver-Coated Gold Nanorods. 2021 Dec 7 1
8 32412821 Kaempferol Protects Against Hydrogen Peroxide-Induced Retinal Pigment Epithelium Cell Inflammation and Apoptosis by Activation of SIRT1 and Inhibition of PARP1. 2020 Sep 2
9 32732457 PARP1 Impedes SIRT1-Mediated Autophagy during Degeneration of the Retinal Pigment Epithelium under Oxidative Stress. 2020 Jul 31 2
10 32872305 Role of Poly [ADP-ribose] Polymerase 1 in Activating the Kirsten ras (KRAS) Gene in Response to Oxidative Stress. 2020 Aug 28 1
11 32901866 TOPK inhibition accelerates oxidative stress‑induced granulosa cell apoptosis via the p53/SIRT1 axis. 2020 Nov 3
12 33046085 Cyclosporin A protects JEG-3 cells against oxidative stress-induced apoptosis by inhibiting the p53 and JNK/p38 signaling pathways. 2020 Oct 12 1
13 33146386 PARP-1 activation after oxidative insult promotes energy stress-dependent phosphorylation of YAP1 and reduces cell viability. 2020 Dec 11 2
14 30254210 CHK2-mediated regulation of PARP1 in oxidative DNA damage response. 2019 Feb 1
15 30431061 Quercetin‑3‑O‑α‑L‑rhamnopyranoside derived from the leaves of Lindera aggregata (Sims) Kosterm. evokes the autophagy‑induced nuclear factor erythroid 2‑related factor 2 antioxidant pathway in human umbilical vein endothelial cells. 2019 Jan 1
16 30496822 Protective Effects of Myxobacterial Extracts on Hydrogen Peroxide-induced Toxicity on Human Primary Astrocytes. 2019 Feb 10 2
17 30502458 LPS protects macrophages from AIF-independent parthanatos by downregulation of PARP1 expression, induction of SOD2 expression, and a metabolic shift to aerobic glycolysis. 2019 Feb 1 5
18 30529301 PARP1-LSD1 functional interplay controls transcription of SOD2 that protects human pro-inflammatory macrophages from death under an oxidative condition. 2019 Feb 1 1
19 30625984 Increasing the TRPM2 Channel Expression in Human Neuroblastoma SH-SY5Y Cells Augments the Susceptibility to ROS-Induced Cell Death. 2019 Jan 8 2
20 30662338 Activation of the Nrf2/HO-1 signaling pathway contributes to the protective effects of baicalein against oxidative stress-induced DNA damage and apoptosis in HEI193 Schwann cells. 2019 1
21 31060395 Protective effect of diphlorethohydroxycarmalol against oxidative stress-induced DNA damage and apoptosis in retinal pigment epithelial cells. 2019 Sep 1
22 31134531 Nrf2 Mediates the Anti-apoptotic and Anti-inflammatory Effects Induced by Gastrodin in Hydrogen Peroxide-Treated SH-SY5Y Cells. 2019 Sep 2
23 31296950 PARP1 regulates DNA damage-induced nucleolar-nucleoplasmic shuttling of WRN and XRCC1 in a toxicant and protein-specific manner. 2019 Jul 11 1
24 31803365 Reactive oxygen/nitrogen species contribute substantially to the antileukemia effect of APO866, a NAD lowering agent. 2019 Nov 19 1
25 29306194 Downregulation of PARP1 transcription by CDK4/6 inhibitors sensitizes human lung cancer cells to anticancer drug-induced death by impairing OGG1-dependent base excision repair. 2018 May 1
26 29472838 Cancer Imprints an Increased PARP-1 and p53-Dependent Resistance to Oxidative Stress on Lymphocytes of Patients That Later Develop Alzheimer's Disease. 2018 2
27 29531462 Dysregulation of PARP1 is involved in development of Barrett's esophagus. 2018 Mar 7 1
28 29629025 Protective effects of perilla oil and alpha linolenic acid on SH-SY5Y neuronal cell death induced by hydrogen peroxide. 2018 Apr 1
29 29874784 Activation of the Nrf2/HO-1 Signaling Pathway Contributes to the Protective Effects of Sargassum serratifolium Extract against Oxidative Stress-Induced DNA Damage and Apoptosis in SW1353 Human Chondrocytes. 2018 Jun 5 1
30 29912609 The Poly(ADP-Ribose)Polymerase-1 Inhibitor 1,5-Isoquinolinediol Attenuate Diabetes-Induced NADPH Oxidase-Derived Oxidative Stress in Retina. 2018 Sep 2
31 30394268 PARP-1 Involvement in Autophagy and Their Roles in Apoptosis of Vascular Smooth Muscle Cells under Oxidative Stress. 2018 3
32 30401461 Bi-allelic ADPRHL2 Mutations Cause Neurodegeneration with Developmental Delay, Ataxia, and Axonal Neuropathy. 2018 Nov 1 1
33 27181592 JNK Activation Contributes to Oxidative Stress-Induced Parthanatos in Glioma Cells via Increase of Intracellular ROS Production. 2017 Jul 1
34 27965414 Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin. 2017 Mar 17 2
35 28055012 AIF-independent parthanatos in the pathogenesis of dry age-related macular degeneration. 2017 Jan 5 5
36 28322340 Signalling mechanisms mediating Zn2+-induced TRPM2 channel activation and cell death in microglial cells. 2017 Mar 21 2
37 28325851 New Quantitative Mass Spectrometry Approaches Reveal Different ADP-ribosylation Phases Dependent On the Levels of Oxidative Stress. 2017 May 3
38 28677799 Baicalin prevents the apoptosis of endplate chondrocytes by inhibiting the oxidative stress induced by H2O2. 2017 Sep 1
39 28761325 Taxifolin protects RPE cells against oxidative stress-induced apoptosis. 2017 1
40 29051731 PARP-1 and p53 Regulate the Increased Susceptibility to Oxidative Death of Lymphocytes from MCI and AD Patients. 2017 1
41 29149203 ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair. 2017 2
42 26138443 Nuclear ULK1 promotes cell death in response to oxidative stress through PARP1. 2016 Feb 1
43 26941573 Melissa Officinalis L. Extracts Protect Human Retinal Pigment Epithelial Cells against Oxidative Stress-Induced Apoptosis. 2016 1
44 26990173 PARP-1 inhibition influences the oxidative stress response of the human lens. 2016 Aug 3
45 27208571 l-Amino acid oxidase isolated from Calloselasma rhodostoma snake venom induces cytotoxicity and apoptosis in JAK2V617F-positive cell lines. 2016 Apr-Jun 1
46 27240523 Exogenous NAD(+) decreases oxidative stress and protects H2O2-treated RPE cells against necrotic death through the up-regulation of autophagy. 2016 May 31 2
47 25145901 Role of heat shock proteins in oxygen radical-induced gastric apoptosis. 2015 Jan 1
48 25433364 Plasma-activated medium induces A549 cell injury via a spiral apoptotic cascade involving the mitochondrial-nuclear network. 2015 Feb 2
49 25720812 3',4',7-Trihydroxyflavone prevents apoptotic cell death in neuronal cells from hydrogen peroxide-induced oxidative stress. 2015 Jun 2
50 25774718 Thrombin or Ca(++)-ionophore-mediated fall in endothelial ATP levels independent of poly(ADP-Ribose) polymerase activity and NAD levels--comparison with the effects of hydrogen peroxide. 2015 3