Cholecalciferol

cytochrome P450 family 24 subfamily A member 1 ; Homo sapiens







40 Article(s)
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1 35436103 Novel DNA Aptamer for CYP24A1 Inhibition with Enhanced Antiproliferative Activity in Cancer Cells. 2022 Apr 27 4
2 33516786 Analysis of vitamin D3 metabolites in survivors of infantile idiopathic hypercalcemia caused by CYP24A1 mutation or SLC34A1 mutation. 2021 Apr 1
3 33838712 Chlorpyrifos alters expression of enzymes involved in vitamin D3 synthesis in skin cells. 2021 May 1
4 34251424 Effect of Vitamin D3 on Regulating Human Tenon's Fibroblasts Activity. 2021 Jul 1 1
5 34298790 Calcitriol Promotes Differentiation of Glioma Stem-Like Cells and Increases Their Susceptibility to Temozolomide. 2021 Jul 16 1
6 34909713 Unlocking the Mechanisms of Cutaneous Adverse Drug Reactions: Activation of the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway by EGFR Inhibitors Triggers Keratinocyte Differentiation and Polarization of Epidermal Immune Responses. 2021 Jun 1
7 31868234 Switches in histone modifications epigenetically control vitamin D3-dependent transcriptional upregulation of the CYP24A1 gene in osteoblastic cells. 2020 Jun 1
8 31907922 Ezh2-dependent H3K27me3 modification dynamically regulates vitamin D3-dependent epigenetic control of CYP24A1 gene expression in osteoblastic cells. 2020 Jun 2
9 30367940 Concise synthesis of 23-hydroxylated vitamin D3 metabolites. 2019 Feb 1
10 31352041 Effects of glucocorticoids on vitamin D3-metabolizing 24-hydroxylase (CYP24A1) in Saos-2 cells and primary human osteoblasts. 2019 Oct 1 1
11 31460236 Synthesis and CYP24A1-Dependent Metabolism of 23-Fluorinated Vitamin D3 Analogues. 2019 Jun 30 1
12 31541729 Introduction of fluorine atoms to vitamin D3 side-chain and synthesis of 24,24-difluoro-25-hydroxyvitamin D3. 2019 Dec 1
13 29528271 Genetic polymorphisms of vitamin D3 metabolizing CYP24A1 and CYP2R1 enzymes in Turkish patients with ischemic stroke. 2018 May 1
14 29726119 Inverse association of vitamin D3 levels with lung cancer mediated by genetic variation. 2018 Jun 1
15 30233662 CYP24A1 depletion facilitates the antitumor effect of vitamin D3 on thyroid cancer cells. 2018 Oct 1
16 27923594 Synthesis of the CYP24A1 major metabolite of 2α-[2-(tetrazol-2-yl)ethyl]-1α,25-dihydroxyvitamin D3. 2017 Oct 1
17 28575224 Response to Antenatal Cholecalciferol Supplementation Is Associated With Common Vitamin D-Related Genetic Variants. 2017 Aug 1 1
18 28665937 Cholecalciferol decreases inflammation and improves vitamin D regulatory enzymes in lymphocytes in the uremic environment: A randomized controlled pilot trial. 2017 1
19 29021285 Placental vitamin D metabolism and its associations with circulating vitamin D metabolites in pregnant women. 2017 Dec 1
20 29165303 Immunoreactivity to CYP24A1, but not vitamin D receptor, is increased in mast cells of keratinocyte skin cancers. 2017 Dec 1 1
21 25201000 Vitamin D-neutralizing CYP24A1 expression, oncogenic mutation states and histological findings of human papillary thyroid cancer. 2015 Mar 1
22 25458314 Phenylbutyrate induces cathelicidin expression via the vitamin D receptor: Linkage to inflammatory and growth factor cytokines pathways. 2015 Feb 1
23 25716812 [Current Topics on Vitamin D. Protein interaction and biological action of active vitamin D compounds]. 2015 Mar 1
24 25835512 Pilot study on the bioactivity of vitamin d in the skin after oral supplementation. 2015 Jun 1
25 26038696 Human hepatic metabolism of the anti-osteoporosis drug eldecalcitol involves sterol C4-methyl oxidase. 2015 Mar 1
26 24081904 Increased expression of CYP24A1 correlates with advanced stages of prostate cancer and can cause resistance to vitamin D3-based therapies. 2014 Jan 5
27 25070320 Genetic variants in CYP2R1, CYP24A1, and VDR modify the efficacy of vitamin D3 supplementation for increasing serum 25-hydroxyvitamin D levels in a randomized controlled trial. 2014 Oct 3
28 25568836 Genetic evidence for a pathogenic role for the vitamin D3 metabolizing enzyme CYP24A1 in multiple sclerosis. 2014 Mar 2
29 23026510 Differential response to 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3) in non-small cell lung cancer cells with distinct oncogene mutations. 2013 Jul 2
30 23375797 Dysregulation of vitamin D3 synthesis leads to enhanced cholangiocarcinoma growth. 2013 Apr 2
31 23456391 Serum vitamin D metabolites in colorectal cancer patients receiving cholecalciferol supplementation: correlation with polymorphisms in the vitamin D genes. 2013 Aug 1
32 23674869 CYP24A1 inhibition facilitates the anti-tumor effect of vitamin D3 on colorectal cancer cells. 2013 May 7 3
33 24494038 Novel vitamin D photoproducts and their precursors in the skin. 2013 Jan 1 1
34 21115105 Valproic acid augments vitamin D receptor-mediated induction of CYP24 by vitamin D3: a possible cause of valproic acid-induced osteomalacia? 2011 Feb 5 2
35 20398751 CYP24A1 splice variants--implications for the antitumorigenic actions of 1,25-(OH)2D3 in colorectal cancer. 2010 Jul 1
36 16902422 Wavelength-dependent induction of CYP24A1-mRNA after UVB-triggered calcitriol synthesis in cultured human keratinocytes. 2007 Jan 1
37 16824767 Dermal fibroblasts pretreated with a sterol Delta7-reductase inhibitor produce 25-hydroxyvitamin D3 upon UVB irradiation. 2006 Oct 2 1
38 15173382 The highly conserved region of the co-repressor Sin3A functionally interacts with the co-repressor Alien. 2004 1
39 15488475 C-25 hydroxylation of 1alpha,24(R)-dihydroxyvitamin D3 is catalyzed by 25-hydroxyvitamin D3-24-hydroxylase (CYP24A1): metabolism studies with human keratinocytes and rat recombinant CYP24A1. 2004 Nov 15 1
40 11686044 Enzymatic studies on the key enzymes of vitamin D metabolism; 1 alpha-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24). 2001 1