Bosentan

solute carrier organic anion transporter family member 1B1 ; Homo sapiens







7 Article(s)
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1 32259555 Drug interaction study of flavonoids toward OATP1B1 and their 3D structure activity relationship analysis for predicting hepatoprotective effects. 2020 May 15 3
2 30652318 Functional characterization for polymorphic organic anion transporting polypeptides (OATP/SLCO1B1, 1B3, 2B1) of monkeys recombinantly expressed with various OATP probes. 2019 Feb 1
3 23738582 Clarithromycin substantially increases steady-state bosentan exposure in healthy volunteers. 2014 Jan 1
4 24842639 CYP2C9, SLCO1B1, SLCO1B3, and ABCB11 polymorphisms in patients with bosentan-induced liver toxicity. 2014 Jun 1
5 23387445 Phase I and II metabolism and MRP2-mediated export of bosentan in a MDCKII-OATP1B1-CYP3A4-UGT1A1-MRP2 quadruple-transfected cell line. 2013 May 2
6 17251982 Inhibitory and inductive effects of rifampin on the pharmacokinetics of bosentan in healthy subjects. 2007 Mar 2
7 17496208 Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil. 2007 Aug 1