| 1 |
34273022 | Post-translational formation of hypusine in eIF5A: implications in human neurodevelopment. | 2022 Apr |
3 |
| 2 |
35243537 | Specific and sensitive GC-MS analysis of hypusine, Nε-(4-amino-2-hydroxybutyl)lysine, a biomarker of hypusinated eukaryotic initiation factor eIF5A, and its application to the bi-ethnic ASOS study. | 2022 Jul |
2 |
| 3 |
35458660 | Investigation of an Allosteric Deoxyhypusine Synthase Inhibitor in P. falciparum. | 2022 Apr 11 |
2 |
| 4 |
32882370 | Hypusination of Eif5a regulates cytoplasmic TDP-43 aggregation and accumulation in a stress-induced cellular model. | 2021 Jan 1 |
2 |
| 5 |
32235505 | Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase. | 2020 Mar 30 |
2 |
| 6 |
32605139 | Inhibition of Eukaryotic Translation Initiation Factor 5A (eIF5A) Hypusination Suppress p53 Translation and Alters the Association of eIF5A to the Ribosomes. | 2020 Jun 27 |
1 |
| 7 |
33326776 | Hypusination Orchestrates the Antimicrobial Response of Macrophages. | 2020 Dec 15 |
2 |
| 8 |
30661771 | Recessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder. | 2019 Feb 7 |
2 |
| 9 |
28819816 | A new non-radioactive deoxyhypusine synthase assay adaptable to high throughput screening. | 2017 Nov |
4 |
| 10 |
27380180 | X-ray absorption spectroscopic characterization of the diferric-peroxo intermediate of human deoxyhypusine hydroxylase in the presence of its substrate eIF5a. | 2016 Sep |
2 |
| 11 |
25689365 | Enantiomers of 3-methylspermidine selectively modulate deoxyhypusine synthesis and reveal important determinants for spermidine transport. | 2015 Jun 19 |
2 |
| 12 |
25865244 | Crystal Structure of the Peroxo-diiron(III) Intermediate of Deoxyhypusine Hydroxylase, an Oxygenase Involved in Hypusination. | 2015 May 5 |
2 |
| 13 |
25029904 | The hypusine-containing translation factor eIF5A. | 2014 Sep-Oct |
2 |
| 14 |
25218134 | The spermidine analogue GC7 (N1-guanyl-1,7-diamineoheptane) induces autophagy through a mechanism not involving the hypusination of eIF5A. | 2014 Dec |
1 |
| 15 |
23943044 | Chemical profiling of deoxyhypusine hydroxylase inhibitors for antimalarial therapy. | 2013 Nov |
2 |
| 16 |
21131325 | Production of active recombinant eIF5A: reconstitution in E.coli of eukaryotic hypusine modification of eIF5A by its coexpression with modifying enzymes. | 2011 Mar |
1 |
| 17 |
21318875 | Assay of deoxyhypusine synthase activity. | 2011 |
2 |
| 18 |
19379712 | The effect of hypusine modification on the intracellular localization of eIF5A. | 2009 Jun 12 |
1 |
| 19 |
18067580 | Mutational analyses of human eIF5A-1--identification of amino acid residues critical for eIF5A activity and hypusine modification. | 2008 Jan |
1 |
| 20 |
16452303 | The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A). | 2006 Feb |
1 |
| 21 |
15262146 | Eukaryotic initiation factor 5A-1 (eIF5A-1) as a diagnostic marker for aberrant proliferation in intraepithelial neoplasia of the vulva. | 2004 Jul |
1 |
| 22 |
12788913 | Reversal of the deoxyhypusine synthesis reaction. Generation of spermidine or homospermidine from deoxyhypusine by deoxyhypusine synthase. | 2003 Aug 29 |
3 |
| 23 |
14749535 | Protein kinase CK2 phosphorylates and interacts with deoxyhypusine synthase in HeLa cells. | 2003 Dec 31 |
1 |
| 24 |
11870779 | Heat stress-induced loss of eukaryotic initiation factor 5A (eIF-5A) in a human pancreatic cancer cell line, MIA PaCa-2, analyzed by two-dimensional gel electrophoresis. | 2002 Feb |
2 |
| 25 |
11976098 | Transcript levels of the eukaryotic translation initiation factor 5A gene peak at early G(1) phase of the cell cycle in the dinoflagellate Crypthecodinium cohnii. | 2002 May |
1 |
| 26 |
11060315 | Hypusine is required for a sequence-specific interaction of eukaryotic initiation factor 5A with postsystematic evolution of ligands by exponential enrichment RNA. | 2001 Jan 26 |
2 |
| 27 |
11278418 | Isolation and characterization of senescence-induced cDNAs encoding deoxyhypusine synthase and eucaryotic translation initiation factor 5A from tomato. | 2001 May 18 |
1 |
| 28 |
11325856 | Isolation of a novel candidate oncogene within a frequently amplified region at 3q26 in ovarian cancer. | 2001 May 1 |
2 |
| 29 |
11104695 | Human deoxyhypusine synthase: interrelationship between binding of NAD and substrates. | 2000 Dec 15 |
2 |
| 30 |
10736626 | Post-translational modifications of eukaryotic initiation factor-5A (eIF-5A) as a new target for anti-cancer therapy. | 1999 |
1 |
| 31 |
9188485 | Enzyme-substrate intermediate formation at lysine 329 of human deoxyhypusine synthase. | 1997 Jun 20 |
2 |
| 32 |
9285094 | Hypusine is essential for eukaryotic cell proliferation. | 1997 May-Jun |
1 |
| 33 |
9405486 | Enzyme-substrate intermediate at a specific lysine residue is required for deoxyhypusine synthesis. The role of Lys329 in human deoxyhypusine synthase. | 1997 Dec 19 |
2 |
| 34 |
8615810 | Molecular cloning and functional expression of human deoxyhypusine synthase cDNA based on expressed sequence tag information. | 1996 Apr 15 |
2 |
| 35 |
24178473 | The polyamine-derived amino acid hypusine: its post-translational formation in eIF-5A and its role in cell proliferation. | 1996 Jun |
1 |
| 36 |
7578077 | Isolation and structural characterization of different isoforms of the hypusine-containing protein eIF-5A from HeLa cells. | 1995 Nov 14 |
3 |
| 37 |
7929297 | Structural features of the eIF-5A precursor required for posttranslational synthesis of deoxyhypusine. | 1994 Oct 14 |
1 |
| 38 |
7985780 | Deoxyhypusine synthase assay based on the use of polyhistidine-tagged substrate and metal chelate-affinity chromatography. | 1994 Aug 15 |
1 |
| 39 |
8314769 | Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. | 1993 Jul 5 |
1 |
| 40 |
1850732 | Comparison of the activities of variant forms of eIF-4D. The requirement for hypusine or deoxyhypusine. | 1991 May 5 |
1 |
| 41 |
1903841 | Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae. | 1991 Jun |
1 |
| 42 |
2121277 | Characterization and reconstitution of a cell free system for NAD(+)-dependent deoxyhypusine formation on the 18 kDa eIF-4D precursor. | 1990 Nov 9 |
1 |
| 43 |
2187871 | The ANB1 locus of Saccharomyces cerevisiae encodes the protein synthesis initiation factor eIF-4D. | 1990 May 25 |
2 |
| 44 |
2492279 | Sequence determination and cDNA cloning of eukaryotic initiation factor 4D, the hypusine-containing protein. | 1989 Jan 25 |
2 |
| 45 |
3117792 | Hypusine formation in protein by a two-step process in cell lysates. | 1987 Nov 5 |
2 |
| 46 |
3091607 | Changes in eIF-4D hypusine modification or abundance are not correlated with translational repression in HeLa cells. | 1986 Sep 25 |
1 |
| 47 |
6423643 | The mammalian hypusine-containing protein, eukaryotic initiation factor 4D. Structural homology of this protein from several species. | 1984 Apr 10 |
1 |