venetoclax

BCL2 apoptosis regulator ; Homo sapiens







278 Article(s)
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1 33853293 Pevonedistat and azacitidine upregulate NOXA (PMAIP1) to increase sensitivity to venetoclax in preclinical models of acute myeloid leukemia. 2022 Apr 1 1
2 34173723 A novel polyethylene glycol (PEG)-drug conjugate of Venetoclax, a Bcl-2 inhibitor, for treatment of acute myeloid leukemia (AML). 2022 Mar 1
3 34332791 Morphologic and molecular analysis of Richter syndrome in chronic lymphocytic leukaemia patients treated with ibrutinib or venetoclax. 2022 Feb 1
4 34728569 Anti-apoptotic MCL1 Protein Represents Critical Survival Molecule for Most Burkitt Lymphomas and BCL2-negative Diffuse Large B-cell Lymphomas. 2022 Jan 2
5 34795418 Inhibitors of Bcl-2 and Bruton's tyrosine kinase synergize to abrogate diffuse large B-cell lymphoma growth in vitro and in orthotopic xenotransplantation models. 2022 Apr 1
6 35185150 Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia. 2022 Feb 21 2
7 35187951 PALVEN: phase Ib trial of palbociclib, letrozole and venetoclax in estrogen receptor- and BCL2-positive advanced breast cancer. 2022 May 1
8 35188042 Enhanced cytotoxicity of bisantrene when combined with venetoclax, panobinostat, decitabine and olaparib in acute myeloid leukemia cells. 2022 Feb 20 1
9 35193595 BCL-2 expression promotes immunosuppression in chronic lymphocytic leukemia by enhancing regulatory T cell differentiation and cytotoxic T cell exhaustion. 2022 Feb 22 1
10 35241842 Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy. 2022 Mar 1
11 35245447 The proteogenomic subtypes of acute myeloid leukemia. 2022 Mar 14 1
12 35352453 Dual targeting of PI3K and BCL-2 overcomes ibrutinib resistance in aggressive mantle cell lymphoma. 2022 May 1
13 35383271 Cyclin-dependent kinase inhibitor fadraciclib (CYC065) depletes anti-apoptotic protein and synergizes with venetoclax in primary chronic lymphocytic leukemia cells. 2022 Jun 1
14 35443750 The BCL-2 inhibitor ABT-199/venetoclax synergizes with proteasome inhibition via transactivation of the MCL-1 antagonist NOXA. 2022 Apr 20 1
15 35454865 Mitochondrial Kv1.3 Channels as Target for Treatment of Multiple Myeloma. 2022 Apr 13 1
16 35491624 Adapted to Survive: Targeting Cancer Cells with BH3 Mimetics. 2022 May 2 1
17 35515507 Age-Adjusted Schedules of Venetoclax and Hypomethylating Agents to Treat Extremely Elderly Patients with Acute Myeloid Leukemia. 2022 1
18 35577568 The BCL2 Inhibitor Venetoclax Plus Rituximab Is Active in MYD88 Wild-Type Polyneuropathy With Anti-MAG Antibodies. 2022 Jul 1
19 35594184 How do we manage t(11;14) plasma cell disorders with venetoclax? 2022 May 20 1
20 35598030 Progress in understanding the mechanisms of resistance to BCL-2 inhibitors. 2022 May 21 1
21 32199933 Venetoclax and decitabine for treatment of relapsed T-cell acute lymphoblastic leukemia: A case report and review of literature. 2021 Sep 4
22 32887697 Venetoclax Increases Intratumoral Effector T Cells and Antitumor Efficacy in Combination with Immune Checkpoint Blockade. 2021 Jan 1
23 33121235 Venetoclax plus bendamustine-rituximab or bendamustine-obinutuzumab in chronic lymphocytic leukemia: final results of a phase 1b study (GO28440). 2021 Nov 1 2
24 33318657 Targeting eIF4F translation initiation complex with SBI-756 sensitises B lymphoma cells to venetoclax. 2021 Mar 1
25 33368455 Targeting BCL-2 with venetoclax and dexamethasone in patients with relapsed/refractory t(11;14) multiple myeloma. 2021 Apr 1 1
26 33459064 Venetoclax for the treatment of elderly or chemotherapy-ineligible patients with acute myeloid leukemia: a step in the right direction or a game changer? 2021 Feb 1
27 33480649 Venetoclax and Decitabine in Pediatric Refractory T-cell Lymphoblastic Lymphoma. 2021 Oct 1 1
28 33495184 Plasma cell leukaemia with t(11;14) not responsive to venetoclax. 2021 Jan 25 1
29 33542074 Emergence of Enzalutamide Resistance in Prostate Cancer is Associated with BCL-2 and IKKB Dependencies. 2021 Apr 15 2
30 33687436 Glycine ameliorates mitochondrial dysfunction caused by ABT-199 in porcine oocytes. 2021 Apr 1 1
31 33743079 New Treatment Options for Older Patients with Acute Myeloid Leukemia. 2021 Mar 20 1
32 33846811 Synergistic effects of LY294002 and ABT199 on the cell cycle in K562, HL60 and KG1a cells. 2021 Jun 2
33 33900450 Ibrutinib combined with venetoclax for the treatment of relapsed/refractory diffuse large B cell lymphoma. 2021 Jun 1
34 33919958 Venetoclax-Based Regimens for Relapsed/Refractory Acute Myeloid Leukemia in a Real-Life Setting: A Retrospective Single-Center Experience. 2021 Apr 14 1
35 33926484 Inhibition of CPT1a as a prognostic marker can synergistically enhance the antileukemic activity of ABT199. 2021 Apr 29 2
36 34012921 Escape From Treatment; the Different Faces of Leukemic Stem Cells and Therapy Resistance in Acute Myeloid Leukemia. 2021 1
37 34036969 Venetoclax nanomedicine alleviates acute lung injury via increasing neutrophil apoptosis. 2021 Jul 7 1
38 34112754 Interrogation of novel CDK2/9 inhibitor fadraciclib (CYC065) as a potential therapeutic approach for AML. 2021 Jun 10 1
39 34331013 Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss. 2021 Sep 1
40 34424320 The ROR1 antibody-drug conjugate huXBR1-402-G5-PNU effectively targets ROR1+ leukemia. 2021 Aug 24 3
41 34426943 How to Sequence Therapies in Waldenström Macroglobulinemia. 2021 Aug 23 1
42 34581757 Phase 1b study of the BET protein inhibitor RO6870810 with venetoclax and rituximab in patients with diffuse large B-cell lymphoma. 2021 Nov 23 1
43 34614506 Adding venetoclax to fludarabine/busulfan RIC transplant for high-risk MDS and AML is feasible, safe, and active. 2021 Dec 28 1
44 31123034 Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models. 2020 Mar 1
45 31171817 Targeting translation initiation by synthetic rocaglates for treating MYC-driven lymphomas. 2020 Jan 1
46 31533509 Mechanisms of intrinsic and acquired resistance to venetoclax in B-cell lymphoproliferative disease. 2020 Feb 2
47 31837377 Autophagic HuR mRNA degradation induces survivin and MCL1 downregulation in YM155-treated human leukemia cells. 2020 Jan 15 1
48 31928108 A single-center retrospective cohort analysis of venetoclax in relapsed/refractory multiple myeloma. 2020 May 1
49 31932844 Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML. 2020 Mar 12 1
50 32035785 Clinical Experience With Venetoclax Combined With Chemotherapy for Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia. 2020 Apr 1