Polyamines

BCL2 apoptosis regulator ; Homo sapiens







11 Article(s)
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1 26796279 The inhibition of PI3K and NFκB promoted curcumin-induced cell cycle arrest at G2/M via altering polyamine metabolism in Bcl-2 overexpressing MCF-7 breast cancer cells. 2016 Feb 1
2 27881234 DENSpm overcame Bcl-2 mediated resistance against Paclitaxel treatment in MCF-7 breast cancer cells via activating polyamine catabolic machinery. 2016 Dec 3
3 25849284 Depletion of the polyamines spermidine and spermine by overexpression of spermidine/spermine N¹-acetyltransferase 1 (SAT1) leads to mitochondria-mediated apoptosis in mammalian cells. 2015 Jun 15 1
4 20940027 Codonopsis lanceolata extract induces G0/G1 arrest and apoptosis in human colon tumor HT-29 cells--involvement of ROS generation and polyamine depletion. 2011 Jan 1
5 21693166 A stabilizing and denaturing dual-effect for natural polyamines interacting with G-quadruplexes depending on concentration. 2011 Aug 1
6 17920946 Novel anti-apoptotic effect of Bcl-2: prevention of polyamine depletion-induced cell death. 2008 Jan 3
7 15994315 Protein phosphatase 2A regulates apoptosis in intestinal epithelial cells. 2005 Sep 2 2
8 16048438 STAT3-mediated transcription of Bcl-2, Mcl-1 and c-IAP2 prevents apoptosis in polyamine-depleted cells. 2005 Dec 1 5
9 15024023 Akt kinase activation blocks apoptosis in intestinal epithelial cells by inhibiting caspase-3 after polyamine depletion. 2004 May 21 1
10 11313919 Regulation of estrogenic and nuclear factor kappa B functions by polyamines and their role in polyamine analog-induced apoptosis of breast cancer cells. 2001 Mar 29 1
11 9661878 Unsymmetrically substituted polyamine analogue induces caspase-independent programmed cell death in Bcl-2-overexpressing cells. 1998 Jul 1 1