Etoposide

BCL2 apoptosis regulator ; Homo sapiens







85 Article(s)
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1 30500985 Systems analysis of phosphorylation-regulated Bcl-2 interactions establishes a model to reconcile the controversy over the significance of Bcl-2 phosphorylation. 2019 Feb 1
2 30213983 Etoposide-resistance in a neuroblastoma model cell line is associated with 13q14.3 mono-allelic deletion and miRNA-15a/16-1 down-regulation. 2018 Sep 13 1
3 27907860 Co-delivery of VP-16 and Bcl-2-targeted antisense on PEG-grafted oMWCNTs for synergistic in vitro anti-cancer effects in non-small and small cell lung cancer. 2017 Feb 1 1
4 28587395 Effectiveness of imatinib mesylate over etoposide in the treatment of sensitive and resistant chronic myeloid leukaemia cells in vitro. 2017 Jun 1
5 27183435 Decreased LRIG1 in Human Ovarian Cancer Cell SKOV3 Upregulates MRP-1 and Contributes to the Chemoresistance of VP16. 2016 May 1
6 27419628 Glutamine deprivation plus BPTES alters etoposide- and cisplatin-induced apoptosis in triple negative breast cancer cells. 2016 Aug 23 1
7 25607114 Resistance of SMMC-7721 hepatoma cells to etoposide in hypoxia is reversed by VEGF inhibitor. 2015 May 2
8 26191229 Up-regulation of VEGF and its receptor in refractory leukemia cells. 2015 1
9 26424010 SPATA4 Counteracts Etoposide-Induced Apoptosis via Modulating Bcl-2 Family Proteins in HeLa Cells. 2015 1
10 23435429 NF-κB is a critical mediator of BRCA1-induced chemoresistance. 2014 Feb 6 1
11 24559410 The dynamic character of the BCL2 promoter i-motif provides a mechanism for modulation of gene expression by compounds that bind selectively to the alternative DNA hairpin structure. 2014 Mar 19 1
12 23161404 Pharmacological inhibition of GSK3 attenuates DNA damage-induced apoptosis via reduction of p53 mitochondrial translocation and Bax oligomerization in neuroblastoma SH-SY5Y cells. 2013 Mar 1
13 23610963 Cytotoxicity of etoposide in cancer cell lines in vitro after BCL-2 and C-RAF gene silencing with antisense oligonucleotides. 2013 Jan-Feb 1
14 23856142 [The effect of Bcl-2 gene silencing on the sensitivity of cell line A549 to chemotherapeutic drugs]. 2013 Mar 1
15 22238053 Quantitative expression analysis of the apoptosis-related genes BCL2, BAX and BCL2L12 in gastric adenocarcinoma cells following treatment with the anticancer drugs cisplatin, etoposide and taxol. 2012 Jun 3
16 22275372 Nrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosis. 2012 Mar 23 1
17 22491967 Differential effects of Bcl-2 and caspases on mitochondrial permeabilization during endogenous or exogenous reactive oxygen species-induced cell death: a comparative study of H₂O₂, paraquat, t-BHP, etoposide and TNF-α-induced cell death. 2012 Aug 1
18 22895528 Etoposide induces a mixed type of programmed cell death and overcomes the resistance conferred by Bcl-2 in Hep3B hepatoma cells. 2012 Oct 5
19 20189983 Apoptosis protection by Mcl-1 and Bcl-2 modulation of inositol 1,4,5-trisphosphate receptor-dependent Ca2+ signaling. 2010 Apr 30 1
20 19410573 Synergistic interaction of proteasome and topoisomerase II inhibition in multiple myeloma. 2009 Aug 15 1
21 19777212 Tunicamycin induces resistance to camptothecin and etoposide in human hepatocellular carcinoma cells: role of cell-cycle arrest and GRP78. 2009 Nov 1
22 17574594 Bcl-2 gene silencing in pediatric epithelial liver tumors. 2008 Jan 1
23 18927073 Caspase-mediated Bak activation and cytochrome c release during intrinsic apoptotic cell death in Jurkat cells. 2008 Dec 19 1
24 18939359 [Changes in etoposide-induced apoptosis of HeLa tumor cells transfected with antisense oligonucleotide for BCL-2 mRNA]. 2008 2
25 19271688 Quantitative analysis of expression level of BCL2 and BAX genes in Hep-2 and HL-60 cells after treatment with etoposide. 2008 1
26 17544220 Lysophosphatidic acid prevents apoptosis of Caco-2 colon cancer cells via activation of mitogen-activated protein kinase and phosphorylation of Bad. 2007 Aug 1
27 17544840 The role of galectin-3 in cancer drug resistance. 2007 Jun 1
28 17785460 A protein kinase Cepsilon-anti-apoptotic kinase signaling complex protects human vascular endothelial cells against apoptosis through induction of Bcl-2. 2007 Nov 2 2
29 16297990 Adrenomedullin prevents apoptosis in prostate cancer cells. 2006 Jan 15 1
30 16682503 Lithium inhibits ceramide- and etoposide-induced protein phosphatase 2A methylation, Bcl-2 dephosphorylation, caspase-2 activation, and apoptosis. 2006 Aug 1
31 16895478 Treatment of MCF-7 cells with taxol and etoposide induces distinct alterations in the expression of apoptosis-related genes BCL2, BCL2L12, BAX, CASPASE-9 and FAS. 2006 Aug 1
32 17384250 Alterations in mRNA expression of apoptosis-related genes BCL2, BAX, FAS, caspase-3, and the novel member BCL2L12 after treatment of human leukemic cell line HL60 with the antineoplastic agent etoposide. 2006 Dec 2
33 15674333 Induction of prosurvival molecules by apoptotic stimuli: involvement of FOXO3a and ROS. 2005 Mar 17 1
34 15817479 Bcl-2 rescues ceramide- and etoposide-induced mitochondrial apoptosis through blockage of caspase-2 activation. 2005 Jun 24 4
35 15829155 Insulin-like growth factor-I decreased etoposide-induced apoptosis in glioma cells by increasing bcl-2 expression and decreasing CPP32 activity. 2005 Jan 3
36 15031723 Specific downregulation of bcl-2 and xIAP by RNAi enhances the effects of chemotherapeutic agents in MCF-7 human breast cancer cells. 2004 May 2
37 15143129 Selective induction of apoptosis by the pyrrolo-1,5-benzoxazepine 7-[[dimethylcarbamoyl]oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia cells occurs via the c-Jun NH2-terminal kinase-dependent phosphorylation and inactivation of Bcl-2 and Bcl-XL. 2004 Sep 1
38 15175350 A Bcr/Abl-independent, Lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2. 2004 Aug 13 1
39 12536201 RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines. 2003 Feb 1
40 12566077 Apoptosis induction by the dual-action DNA- and protein-reactive antitumor drug irofulven is largely Bcl-2-independent. 2003 Feb 15 1
41 14499628 Bcl-2 prevents abnormal mitochondrial proliferation during etoposide-induced apoptosis. 2003 Oct 1 1
42 14575542 [Enhanced apoptosis-inducing effect of etoposide on leukemic cell lines M-07e and TF-1 by the proteasome inhibitor Z-LLL-CHO]. 2003 Oct 1
43 11815602 Fibroblast growth factor-2 induces translational regulation of Bcl-XL and Bcl-2 via a MEK-dependent pathway: correlation with resistance to etoposide-induced apoptosis. 2002 Apr 5 1
44 11861801 Distinct pathways of apoptosis triggered by FTY720, etoposide, and anti-Fas antibody in human T-lymphoma cell line (Jurkat cells). 2002 Mar 1
45 12063570 Ciprofloxacin inhibits cell growth and synergises the effect of etoposide in hormone resistant prostate cancer cells. 2002 Jul 1
46 12520735 [Bcl-2 antisense oligodeoxynucleotide enhances araninosyl cytosine-induced apoptosis of primary leukemia cells]. 2002 Dec 1
47 12533044 Chemotherapy induces bcl-2 cleavage in lymphoid leukemic cell lines. 2002 Nov 1
48 11279616 Connexin 43 (cx43) enhances chemotherapy-induced apoptosis in human glioblastoma cells. 2001 Apr 1 1
49 11402324 Bcl-2 expression in F-MuLV-induced erythroleukemias: a role for the anti-apoptotic action of Bcl-2 during tumor progression. 2001 Apr 26 2
50 11484935 Anticancer drugs induce necrosis of human endothelial cells involving both oncosis and apoptosis. 2001 Jun 1