Melatonin

BCL2 apoptosis regulator ; Homo sapiens







76 Article(s)
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1 34952259 Effect of astaxanthin and melatonin on cell viability and DNA damage in human breast cancer cell lines. 2022 Jan 1
2 35365454 [Melatonin inhibits growth and metastasis of MDA-MB-231 breast cancer cells by activating autophagy]. 2022 Feb 20 5
3 35430637 Melatonin induces apoptosis and cell cycle arrest in cervical cancer cells via inhibition of NF-κB pathway. 2022 Apr 17 1
4 35636434 Melatonin Increases the Sensitivity of Osteosarcoma Cells to Chemotherapy Drug Cisplatin. 2022 May 30 2
5 33709108 Melatonin promotes male reproductive performance and increases testosterone synthesis in mammalian Leydig cells†. 2021 Jun 4 1
6 34087693 Molecular targets for the management of gastrointestinal cancer using melatonin, a natural endogenous body hormone. 2021 Aug 4
7 34580235 Melatonin inhibits proliferation, migration, and invasion by inducing ROS-mediated apoptosis via suppression of the PI3K/Akt/mTOR signaling pathway in gallbladder cancer cells. 2021 Sep 27 1
8 31735743 Melatonin protects against Epirubicin-induced ovarian damage. 2020 Feb 14 1
9 32210629 Melatonin Regulates Cisplatin Resistance and Glucose Metabolism Through Hippo Signaling in Hepatocellular Carcinoma Cells. 2020 4
10 32392192 [Melatonin Induces Apoptotic Cell Death in 3T3-L1 Preadipocytes]. 2020 Mar-Apr 2
11 32598308 Melatonin inhibits high glucose-induced ox-LDL/LDL expression and apoptosis in human umbilical endothelial cells. 2020 Jun 29 1
12 33352965 Melatonin Protects Cholangiocytes from Oxidative Stress-Induced Proapoptotic and Proinflammatory Stimuli via miR-132 and miR-34. 2020 Dec 18 1
13 33488926 Melatonin Protects Goat Spermatogonial Stem Cells against Oxidative Damage during Cryopreservation by Improving Antioxidant Capacity and Inhibiting Mitochondrial Apoptosis Pathway. 2020 1
14 33571963 Nanomolar melatonin influences insulin synthesis and secretion in rat insulinoma INS-1E cells. 2020 Oct 1
15 30793438 Effect of melatonin on regulation of apoptosis and steroidogenesis in cultured buffalo granulosa cells. 2019 Apr 1
16 31077716 Modulation of apoptosis by melatonin for improving cancer treatment efficiency: An updated review. 2019 Jul 1 1
17 31247931 Melatonin Prevents Oxidative Stress-Induced Mitochondrial Dysfunction and Apoptosis in High Glucose-Treated Schwann Cells via Upregulation of Bcl2, NF-κB, mTOR, Wnt Signalling Pathways. 2019 Jun 26 2
18 31358006 Melatonin attenuates cadmium-induced ovulatory dysfunction by suppressing endoplasmic reticulum stress and cell apoptosis. 2019 Jul 29 1
19 31408847 Melatonin enhances porcine embryo development via the Nrf2/ARE signaling pathway. 2019 Oct 1
20 31870319 Inhibition of autophagy triggers melatonin-induced apoptosis in glioblastoma cells. 2019 Dec 23 2
21 29207126 Melatonin enhances the apoptotic effects and modulates the changes in gene expression induced by docetaxel in MCF‑7 human breast cancer cells. 2018 Feb 1
22 29363570 Melatonin reduces oxidative damage in mouse granulosa cells via restraining JNK-dependent autophagy. 2018 Mar 2
23 29436019 Melatonin attenuates homocysteine-induced injury in human umbilical vein endothelial cells. 2018 Jun 1
24 29725496 Melatonin Inhibits Reactive Oxygen Species-Driven Proliferation, Epithelial-Mesenchymal Transition, and Vasculogenic Mimicry in Oral Cancer. 2018 1
25 30174783 Protective Effect of Melatonin against Oxidative Stress-Induced Apoptosis and Enhanced Autophagy in Human Retinal Pigment Epithelium Cells. 2018 1
26 30210141 Melatonin Upregulates Nuclear Factor Erythroid-2 Related Factor 2 (Nrf2) and Mediates Mitophagy to Protect Against Early Brain Injury After Subarachnoid Hemorrhage. 2018 Sep 13 1
27 30248940 Melatonin Can Strengthen the Effect of Retinoic Acid in HL-60 Cells. 2018 Sep 21 2
28 31565647 Stimulatory Effect of Indolic Hormone on As2O3 Cytotoxicity in Breast Cancer Cells: NF-κB-dependent Mechanism of Action of Melatonin. 2018 Summer 1
29 27785753 Phytanic Acid-Induced Neurotoxicological Manifestations and Apoptosis Ameliorated by Mitochondria-Mediated Actions of Melatonin. 2017 Nov 1
30 28123844 Targeting NF-κB/AP-2β signaling to enhance antitumor activity of cisplatin by melatonin in hepatocellular carcinoma cells. 2017 1
31 28246472 Melatonin, a novel selective ATF-6 inhibitor, induces human hepatoma cell apoptosis through COX-2 downregulation. 2017 Feb 14 1
32 28415572 Inhibition of iron overload-induced apoptosis and necrosis of bone marrow mesenchymal stem cells by melatonin. 2017 May 9 1
33 29051117 Melatonin reduces oxidative damage and upregulates heat shock protein 90 expression in cryopreserved human semen. 2017 Dec 1
34 26607805 Melatonin enhances arsenic trioxide-induced cell death via sustained upregulation of Redd1 expression in breast cancer cells. 2016 Feb 15 1
35 26672764 Melatonin inhibits AP-2β/hTERT, NF-κB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells. 2016 Jan 19 1
36 27220903 Melatonin protects podocytes from angiotensin II-induced injury in an in vitro diabetic nephropathy model. 2016 Jul 1
37 27452798 Melatonin modulates glucocorticoid receptor mediated inhibition of antioxidant response and apoptosis in peripheral blood mononuclear cells. 2016 Nov 15 2
38 27465521 Melatonin enhances hyperthermia-induced apoptotic cell death in human leukemia cells. 2016 Oct 2
39 27477115 Melatonin modulates the functions of porcine granulosa cells via its membrane receptor MT2 in vitro. 2016 Sep 2
40 27666165 Melatonin induces cell apoptosis in Mia PaCa-2 cells via the suppression of nuclear factor-κB and activation of ERK and JNK: A novel therapeutic implication for pancreatic cancer. 2016 Nov 1
41 25281200 Cytoprotective effect of melatonin against hypoxia/serum deprivation-induced cell death of bone marrow mesenchymal stem cells in vitro. 2015 Feb 5 1
42 25528518 The Keap1-Nrf2-antioxidant response element pathway: a review of its regulation by melatonin and the proteasome. 2015 Feb 5 1
43 25702644 Melatonin promotes Bax sequestration to mitochondria reducing cell susceptibility to apoptosis via the lipoxygenase metabolite 5-hydroxyeicosatetraenoic acid. 2015 Mar 3
44 25752481 Melatonin induces apoptosis of colorectal cancer cells through HDAC4 nuclear import mediated by CaMKII inactivation. 2015 May 2
45 25904702 Melatonin pretreatment of human adipose tissue-derived mesenchymal stromal cells enhances their prosurvival and protective effects on human kidney cells. 2015 Jun 15 1
46 25998836 Melatonin decreases cell proliferation, impairs myogenic differentiation and triggers apoptotic cell death in rhabdomyosarcoma cell lines. 2015 Jul 1
47 26025920 Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells. 2015 Jul 10 1
48 26645893 Melatonin Induces Cell Apoptosis in AGS Cells Through the Activation of JNK and P38 MAPK and the Suppression of Nuclear Factor-Kappa B: a Novel Therapeutic Implication for Gastric Cancer. 2015 2
49 24799992 Melatonin attenuates cisplatin-induced HepG2 cell death via the regulation of mTOR and ERCC1 expressions. 2014 Apr 27 1
50 25000265 Overcoming hypoxic-resistance of tumor cells to TRAIL-induced apoptosis through melatonin. 2014 Jul 4 1