Sorafenib

protein tyrosine phosphatase non-receptor type 6 ; Homo sapiens







9 Article(s)
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1 28084011 Sorafenib analogue SC-60 induces apoptosis through the SHP-1/STAT3 pathway and enhances docetaxel cytotoxicity in triple-negative breast cancer cells. 2017 Mar 2
2 26959741 SH2 domain-containing phosphatase 1 regulates pyruvate kinase M2 in hepatocellular carcinoma. 2016 Apr 19 3
3 27580057 Regorafenib (Stivarga) pharmacologically targets epithelial-mesenchymal transition in colorectal cancer. 2016 Sep 27 2
4 26039995 Sorafenib and its derivative SC-1 exhibit antifibrotic effects through signal transducer and activator of transcription 3 inhibition. 2015 Jun 9 2
5 23908138 Discovery of novel Src homology region 2 domain-containing phosphatase 1 agonists from sorafenib for the treatment of hepatocellular carcinoma. 2014 Jan 13
6 24275147 SC-60, a dimer-based sorafenib derivative, shows a better anti-hepatocellular carcinoma effect than sorafenib in a preclinical hepatocellular carcinoma model. 2014 Jan 1
7 24736071 Signal transducer and activator of transcription 3 as molecular therapy for non-small-cell lung cancer. 2014 Apr 2
8 23938089 Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells. 2013 3
9 22871485 Blockade of STAT3 activation by sorafenib derivatives through enhancing SHP-1 phosphatase activity. 2012 Sep 2